Semen pH ve likefaksiyon süresi motilite ve morfoloji üzerinde etkili midir?

Year 2021, Volume: 16 Issue: 2, 172 - 177, 07.07.2021

Mehmet Kutlu Demirkol Sefa Resim Neslihan Temiz Mustafa Bilal Hamarat Osman Barut

https://doi.org/10.17517/ksutfd.828863

Abstract

AMAÇ
Lİkefaksiyon süresi ve semen pH değerlerinin sperm fonksiyonları ile ilişkili olup olmadığı konusunda yeterli çalışma bulunmamaktadır. Bu nedenle, bu çalışmada pH ve lİkefaksiyon süresi ile ana semen parametreleri arasında bir ilişki olup olmadığı değerlendirilmesi hedeflendi.
YÖNTEM ve GEREÇ
Veriler normal ve anormal olarak gruplara ayrıldı ve pH ve likefaksiyon süreleri açısından karşılaştırıldı. Örnekler ayrıca semen pH değerine göre asidik (<7.2), normal (7.2-8.0) ve bazik (> 8.0) ve likefaksiyon süresine göre normal sıvılaştırma (≤30 dak.) ve yavaş sıvılaştırma (> 30 dak.) şeklinde gruplandırıldı, ve daha sonra konsantrasyon, motilite ve morfoloji bozuklukları açısından karşılaştırıldı.
BULGULAR
600 semen örneğinden 400'ü (% 66.7) anormal, 200'ü (% 33.3) normal olarak gruplandırıldı. Anormal grubun medyan pH ve sıvılaşma süresi normal gruptan istatistiksel olarak daha yüksekti (her ikisi de, p <0,01). Semen pH ve likefaksiyon süreleri astenoospermi, teratoospermi ve astenoteratospermi gruplarında anlamlı olarak daha yüksekti (tümü için p <0.01). Bazik ph (> 8.0) grubunun konsantrasyonu, progresif motilitesi ve morfolojisi hem asidik hem de normal ph gruplarından anlamlı olarak daha düşüktü (hepsi için p <0.01). Bunun aksine, sıvılaşma zaman gruplarının morfolojileri arasında sadece anlamlı fark vardı (p = 0.02).
SONUÇ
Anormal ve normal gruplarda semen pH ve likefaksiyon süresi değerleri anlamlı derecede farklıydı ve bu fark astenoospermi, teratospermi ve astenoteratospermisi olanlarda belirgindi.Bu ilişkileri daha iyi anlamak için kontrol grubu olarak kanıtlanmış fertil erkeklerle çalışmalar yapılmalıdır.

Keywords

Likefaksiyon süresi, morfoloji, motilite, semen pH

Is seminal pH and liquefaction time effective on motility and morphology?

Abstract

Objective
There are not enough reports about whether liquefaction time and semen pH values are related to sperm functions. Therefore, this study aimed to evaluate whether there is a relationship between pH and liquefaction time and major semen parameters.
Material and Methods
The data were divided into groups as normal and abnormal and compared in terms of pH and liquefaction times. The samples were also grouped according to semen pH as acidic (<7.2), normal ( 7.2-8.0) and basic (>8.0) and liquefaction time as normal liquefying (≤30 min.) and slow liquefying (> 30 min.), and then were compared in terms of the normal/abnormal status of concentration, motility and morphology.
Results
Of the 600 semen samples, 400 (66.7%) were grouped as abnormal and 200 (33.3%) as normal. The median pH and liquefaction time of the abnormal group were statistically higher than the normal group (both, p <0,01). The seminal pH and liquefaction times were significantly higher in asthenozoospermia, teratozoospermia and asthenoteratozoospermia groups (for all, p <0.01). The concentration, progressive motility and morphology of the basic ph (>8.0) group was significantly lower than both acidic and normal ph groups (for all, p <0.01). Unlike, there was only significant difference between the morphologies of liquefaction time groups (p=0.02).
Conclusion
The seminal pH and liquefaction time values in the abnormal and normal groups were significantly different and this difference was evident in those with asthenozoospermia, teratozoospermia and asthenoteratozoospermia. To understand these relationships better, studies with proven fertile men as a control group should be performed.

Keywords

Liquefaction time, morphology, motility, semen pH

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