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Multi-Drug Use in the Elderly

Year 2017, Volume: 9 Issue: 6, 0 - 0, 27.11.2017

Abstract

References

  • Kaynaklar 1. Hilmer, S.N., McLachlan, A.J. & Le Couteur, D.G. Clinicalpharmacology in the geriatric patient. Fundam. Clin. Phar-macol. 21, 217–230 (2007). 2. Van Spall, H.G., Toren, A., Kiss, A. & Fowler, R.A. Eligibi-lity criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling re-view. JAMA 297, 1233–1240 (2007). 3. Boyd, C.M., Darer, J., Boult, C., Fried, L.P., Boult, L. & Wu,A.W. Clinical practice guidelines and quality of care for ol-der patients with multiple comorbid diseases: implications forpay for performance. JAMA 294, 716–724 (2005). 4. LeSage J: Polypharmacy in geriatric patients. Nurs Clin NorthAm 1991;26:273-290 5. Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P,Lindau ST: Use of prescription and over-the-counter medica-tions and dietary supplements among older adults in the Uni-ted States. Jama 2008;300:2867-2878. 6. Prescriptions dispensed in community statistics for 1989–1999:England. Statistical Bulletin. [article online], 2014. Availab-le from https://www.gov.uk/government/publications?key-words=&publication_filter_option=all&topics%5B%5D=all&departments%5B%5D=department-ofhealth& official_do-cument_status=all&world_locations%5B%5D=all&from_date=&to_date=. Erişim 5 Ekim 2017 7. Bahat G, Tufan F, Bahat Z, Tufan A, Aydin Y, Akpinar TS, Na-dir S, Erten N, Karan MA: Comorbidities, polypharmacy, func-tionality and nutritional status in Turkish community-dwellingfemale elderly. Aging Clin Exp Res 2014;26:255-259 8. Bahat G, Tufan F, Bahat Z, Aydin Y, Tufan A, Akpinar TS, Er-ten N, Karan MA: Assessments of functional status, comor-bidities, polypharmacy, nutritional status and sarcopenia inTurkish community-dwelling male elderly. Aging Male 2013;16:67-72 9. Medicines and older people: implementing medicines-relatedaspects of the NSF for older people 2015. Available fromhttp://webarchive.nationalarchives.gov.uk/20130107105354/http://www.dh.gov.uk/prod_consum_dh/groups/ dh_digitalas-sets/@dh/@en/documents/digitalasset/dh_4067247.pdf. Eri-şim 5 Ekim 2017. 10. Drug prescribing for older adults [article online], 2014. Sec-tion Editor: Schmader KE, Deputy Editor: Sokol HN. Avai-lable from http://www.uptodate.com/contents/drug-prescribing-for-olderadults? topicKey=PC%2F3013&elapsedTimeMs=4&view=print&displayedView=full. Erişim 5 Ekim 2017. 11.Nobili A, Licata G, Salerno F, et al. Polypharmacy, length ofhospital stay and inpatient mortality among elderly patientsin internal medicine wards. The REPOSI study. Eur J ClinPharmacol. 2011; 67: 507–519. 12. Mallet L, Spinewine A, Huang A. The challenge of managingdrug interactions in elderly people. Lancet. 2007; 370:185–91. 13. Doan J, Zakrewski-Jakubiak H, Roy J, et al. Prevalence andrisk of potential cytochrome p450-mediated drug-drug inte-ractions in older hospitalized patients with polypharmacy. AnnPharmacother. 2013; 47:324–32. 14. Magaziner J, Cadigan DA, Fedder DO, Hebel JR. Medica-tion use and functional decline among community-dwelling older women. J Aging Health. 1989; 1:470–484. 15. Jyrkka J, Enlund H, Lavikainen P, et al. Association of polyp-harmacy with nutritional status, functional ability and cog-nitive capacity over a three-year period in an elderly popu-lation. Pharmacoepidemiol Drug Saf. 2010; 20:514–522. 35. 16. Fletcher PC, Berg K, Dalby DM, Hirdes JP. Risk factors forfalling among community-based seniors. J Patient Saf. 2009;5:61–66. 17. Tromp AM, Plujim SM, Smit JH, et al. Fall-risk screening test:a positive study of predictors for falls in community-dwellingelderly. J Clin Epidemiol. 2001; 54:837–844. 18. Damian J, Pastor-Barriuso R, Valderrama-Gama E, de Ped-ro-Cuesta J. Factors associated with falls among olderadults living in institutions. BMC Geriatr. 2013; 13:6. 19. Nuotio M, Jylha M, Luukkaala T, Tammela T. Health prob-lems associated with lower urinary tract symptoms in olderwomen. Scand J Prim Care. 2005; 23:209–214. 20. Heuberger RA, Caudell K. Polypharmacy and nutritional sta-tus in older adults. Drugs Aging. 2011; 28:315–323. 21. Yaşlılarda İlaç Kullanımında Güncel Sorunlar Ve Çözüm Öne-rileri Çalıştayı 26-27 Mayıs 2015 Ankara Çalıştay Raporu.Pal-yatif Bakım: Aile Hekimliği Açısından Genel Bir Bakış

Yaşlılarda Çoklu İlaç Kullanımı

Year 2017, Volume: 9 Issue: 6, 0 - 0, 27.11.2017

Abstract


Giriş

Günümüzdeki demografik eğilimin süreceği
varsayımından hareketle yapılan projeksiyonlar, 21. yüzyılın tüm
dünyadaki beklentilere paralel olarak Türkiye’de de yaşlı yüzyılı
olacağına işaret etmektedir. Tüm dünyada ve Türkiye’de 65 yaş üzerindeki
kişi sayısındaki artış göz önüne alındığında, polifarmasi yaşlı
erişkinlerde önemli bir sağlık sorunu olarak karşımıza çıkmaktadır.
Polifarmasinin sözlük tanımı, iki Yunanca sözcükten türetildiğini ortaya
koymakta-dır "poli" kelimesi; birden fazla anlamına gelmektedir
"farmasi", kelimesi de ilaç anla-mındaki  "pharmacon"’ dan türetilmiştir
(1). Polifarmasi, değişik tanımlamalara sahipolmakla beraber günde 4-5
adet ve üzeri ilaç kullanımı, klinik endikasyondan fazla ilaçkullanımı,
en az bir gereksiz ilaç kullanımı şeklinde ifade edilebilir (1-3).

References

  • Kaynaklar 1. Hilmer, S.N., McLachlan, A.J. & Le Couteur, D.G. Clinicalpharmacology in the geriatric patient. Fundam. Clin. Phar-macol. 21, 217–230 (2007). 2. Van Spall, H.G., Toren, A., Kiss, A. & Fowler, R.A. Eligibi-lity criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling re-view. JAMA 297, 1233–1240 (2007). 3. Boyd, C.M., Darer, J., Boult, C., Fried, L.P., Boult, L. & Wu,A.W. Clinical practice guidelines and quality of care for ol-der patients with multiple comorbid diseases: implications forpay for performance. JAMA 294, 716–724 (2005). 4. LeSage J: Polypharmacy in geriatric patients. Nurs Clin NorthAm 1991;26:273-290 5. Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P,Lindau ST: Use of prescription and over-the-counter medica-tions and dietary supplements among older adults in the Uni-ted States. Jama 2008;300:2867-2878. 6. Prescriptions dispensed in community statistics for 1989–1999:England. Statistical Bulletin. [article online], 2014. Availab-le from https://www.gov.uk/government/publications?key-words=&publication_filter_option=all&topics%5B%5D=all&departments%5B%5D=department-ofhealth& official_do-cument_status=all&world_locations%5B%5D=all&from_date=&to_date=. Erişim 5 Ekim 2017 7. Bahat G, Tufan F, Bahat Z, Tufan A, Aydin Y, Akpinar TS, Na-dir S, Erten N, Karan MA: Comorbidities, polypharmacy, func-tionality and nutritional status in Turkish community-dwellingfemale elderly. Aging Clin Exp Res 2014;26:255-259 8. Bahat G, Tufan F, Bahat Z, Aydin Y, Tufan A, Akpinar TS, Er-ten N, Karan MA: Assessments of functional status, comor-bidities, polypharmacy, nutritional status and sarcopenia inTurkish community-dwelling male elderly. Aging Male 2013;16:67-72 9. Medicines and older people: implementing medicines-relatedaspects of the NSF for older people 2015. Available fromhttp://webarchive.nationalarchives.gov.uk/20130107105354/http://www.dh.gov.uk/prod_consum_dh/groups/ dh_digitalas-sets/@dh/@en/documents/digitalasset/dh_4067247.pdf. Eri-şim 5 Ekim 2017. 10. Drug prescribing for older adults [article online], 2014. Sec-tion Editor: Schmader KE, Deputy Editor: Sokol HN. Avai-lable from http://www.uptodate.com/contents/drug-prescribing-for-olderadults? topicKey=PC%2F3013&elapsedTimeMs=4&view=print&displayedView=full. Erişim 5 Ekim 2017. 11.Nobili A, Licata G, Salerno F, et al. Polypharmacy, length ofhospital stay and inpatient mortality among elderly patientsin internal medicine wards. The REPOSI study. Eur J ClinPharmacol. 2011; 67: 507–519. 12. Mallet L, Spinewine A, Huang A. The challenge of managingdrug interactions in elderly people. Lancet. 2007; 370:185–91. 13. Doan J, Zakrewski-Jakubiak H, Roy J, et al. Prevalence andrisk of potential cytochrome p450-mediated drug-drug inte-ractions in older hospitalized patients with polypharmacy. AnnPharmacother. 2013; 47:324–32. 14. Magaziner J, Cadigan DA, Fedder DO, Hebel JR. Medica-tion use and functional decline among community-dwelling older women. J Aging Health. 1989; 1:470–484. 15. Jyrkka J, Enlund H, Lavikainen P, et al. Association of polyp-harmacy with nutritional status, functional ability and cog-nitive capacity over a three-year period in an elderly popu-lation. Pharmacoepidemiol Drug Saf. 2010; 20:514–522. 35. 16. Fletcher PC, Berg K, Dalby DM, Hirdes JP. Risk factors forfalling among community-based seniors. J Patient Saf. 2009;5:61–66. 17. Tromp AM, Plujim SM, Smit JH, et al. Fall-risk screening test:a positive study of predictors for falls in community-dwellingelderly. J Clin Epidemiol. 2001; 54:837–844. 18. Damian J, Pastor-Barriuso R, Valderrama-Gama E, de Ped-ro-Cuesta J. Factors associated with falls among olderadults living in institutions. BMC Geriatr. 2013; 13:6. 19. Nuotio M, Jylha M, Luukkaala T, Tammela T. Health prob-lems associated with lower urinary tract symptoms in olderwomen. Scand J Prim Care. 2005; 23:209–214. 20. Heuberger RA, Caudell K. Polypharmacy and nutritional sta-tus in older adults. Drugs Aging. 2011; 28:315–323. 21. Yaşlılarda İlaç Kullanımında Güncel Sorunlar Ve Çözüm Öne-rileri Çalıştayı 26-27 Mayıs 2015 Ankara Çalıştay Raporu.Pal-yatif Bakım: Aile Hekimliği Açısından Genel Bir Bakış
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Primary Language Turkish
Journal Section makaleler
Authors

Özlem Tanrıöver

Publication Date November 27, 2017
Published in Issue Year 2017 Volume: 9 Issue: 6

Cite

APA Tanrıöver, Ö. (2017). Yaşlılarda Çoklu İlaç Kullanımı. Klinik Tıp Aile Hekimliği, 9(6).
AMA Tanrıöver Ö. Yaşlılarda Çoklu İlaç Kullanımı. Aile Hekimliği. November 2017;9(6).
Chicago Tanrıöver, Özlem. “Yaşlılarda Çoklu İlaç Kullanımı”. Klinik Tıp Aile Hekimliği 9, no. 6 (November 2017).
EndNote Tanrıöver Ö (November 1, 2017) Yaşlılarda Çoklu İlaç Kullanımı. Klinik Tıp Aile Hekimliği 9 6
IEEE Ö. Tanrıöver, “Yaşlılarda Çoklu İlaç Kullanımı”, Aile Hekimliği, vol. 9, no. 6, 2017.
ISNAD Tanrıöver, Özlem. “Yaşlılarda Çoklu İlaç Kullanımı”. Klinik Tıp Aile Hekimliği 9/6 (November 2017).
JAMA Tanrıöver Ö. Yaşlılarda Çoklu İlaç Kullanımı. Aile Hekimliği. 2017;9.
MLA Tanrıöver, Özlem. “Yaşlılarda Çoklu İlaç Kullanımı”. Klinik Tıp Aile Hekimliği, vol. 9, no. 6, 2017.
Vancouver Tanrıöver Ö. Yaşlılarda Çoklu İlaç Kullanımı. Aile Hekimliği. 2017;9(6).