Review
Year 2018,
Volume: 10 Issue: 1, 17 - 18, 30.01.2018
Abstract
Aktif hormon sekresyonu yapmayan hipofiz tümörleri nonfonksiyonel adenom olarak
adlandırılmaktadır. Tüm hipofiz adenomları içerisindeki oranları %30-35’dir. Bunların
ekseriside (%80-90) gonodotropik adenomlar tarafından oluşturulmaktadır. Gonadotrop
adenomlar en sık 50 yaş üzerinde erkeklerde izlenir. Hastalar genellikle görme
alanında bozulma ve başağrısı gibi nörolojik semptomlar ya da hipofizer yetmezlik
şeklinde klinik gösterirler. Gonadotropik adenomu bulunan hastaların tedavisindeki amaçlar;
nörolojik semptomların düzeltilmesi, nükse müsaade etmeyecek şekilde mümkünse
makroadenom dokusunun tamamen çıkartılması ve normal hipofiz dokusunun basısı
sonucu gelişen hormonal yetmezliğin yönetimidir.
Keywords
References
- 1. Chaidarun SS, Klibanski A. Gonadotropinomas. Semin Reprod Med. 2002 Nov;20(4):339-48. 2. Daneshdoost L, Gennarelli TA, Bashey HM, Savino PJ, Sergott RC, Bosley TM, Snyder PJ. Recognition of gonadotroph adenomas in women. N Engl J Med. 1991;324(9):589. 3. Alexander JM, Biller BM, Bikkal H, Zervas NT, Arnold A, Klibanski A. Clinically nonfunctioning pituitary tumors are monoclonal in origin. J Clin Invest. 1990;86(1):336. 4. Tashiro H, Katabuchi H, Ohtake H, Kaku T, Ushio Y, Okamura HA follicle-stimulating hormone-secreting gonadotroph adenoma with ovarian enlargement in a 10-year-old girl.Fertil Steril. 1999;72(1):158. 5. Snyder PJ. Gonadotroph cell adenomas of the pituitary. Endocr Rev. 1985;6(4):552. 6. Daneshdoost L, Gennarelli TA, Bashey HM, Savino PJ, Sergott RC, Bosley TM, Snyder PJ. Identification of gonadotroph adenomas in men with clinically nonfunctioning adenomas by the luteinizing hormone beta subunit response to thyrotropinreleasing hormone. J Clin Endocrinol Metab. 1993;77(5):1352. 7. Dekkers OM, Pereira AM, Romijn JA. Treatment and follow-up of clinically nonfunctioning pituitary macroadenomas. J Clin Endocrinol Metab. 2008 Oct;93(10) 3717-26. Epub 2008 Aug 5. 8. Ceylan S, Anik I, Koc K, Ciftci E, Cabuk B. Endoscopic approach to cavernous sinus aneurysm. Turk Neurosurg. 2013;23(3):404-6.
Year 2018,
Volume: 10 Issue: 1, 17 - 18, 30.01.2018
Abstract
References
- 1. Chaidarun SS, Klibanski A. Gonadotropinomas. Semin Reprod Med. 2002 Nov;20(4):339-48. 2. Daneshdoost L, Gennarelli TA, Bashey HM, Savino PJ, Sergott RC, Bosley TM, Snyder PJ. Recognition of gonadotroph adenomas in women. N Engl J Med. 1991;324(9):589. 3. Alexander JM, Biller BM, Bikkal H, Zervas NT, Arnold A, Klibanski A. Clinically nonfunctioning pituitary tumors are monoclonal in origin. J Clin Invest. 1990;86(1):336. 4. Tashiro H, Katabuchi H, Ohtake H, Kaku T, Ushio Y, Okamura HA follicle-stimulating hormone-secreting gonadotroph adenoma with ovarian enlargement in a 10-year-old girl.Fertil Steril. 1999;72(1):158. 5. Snyder PJ. Gonadotroph cell adenomas of the pituitary. Endocr Rev. 1985;6(4):552. 6. Daneshdoost L, Gennarelli TA, Bashey HM, Savino PJ, Sergott RC, Bosley TM, Snyder PJ. Identification of gonadotroph adenomas in men with clinically nonfunctioning adenomas by the luteinizing hormone beta subunit response to thyrotropinreleasing hormone. J Clin Endocrinol Metab. 1993;77(5):1352. 7. Dekkers OM, Pereira AM, Romijn JA. Treatment and follow-up of clinically nonfunctioning pituitary macroadenomas. J Clin Endocrinol Metab. 2008 Oct;93(10) 3717-26. Epub 2008 Aug 5. 8. Ceylan S, Anik I, Koc K, Ciftci E, Cabuk B. Endoscopic approach to cavernous sinus aneurysm. Turk Neurosurg. 2013;23(3):404-6.
There are 1 citations in total.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Internal Diseases |
| Journal Section | makaleler |
| Authors | |
| Publication Date | January 30, 2018 |
| Published in Issue | Year 2018 Volume: 10 Issue: 1 |
