Preeklamptik Anne Bebeklerinin 36. Aydaki Nörogelişimlerinin Değerlendirilmesi

Year 2018, Volume: 10 Issue: 4, 0 - 0, 25.07.2018

Fahri Ovalı

Abstract

ÖzPreeklampsi değişik klinik tablolarla seyredebilen, preterm doğum, maternal vefetal/neonatal morbidite ile mortalitenin başlıca nedenlerinden biridir ve nörogelişim problemlerine neden olabilmektedir. Çalışmamızda 32 hafta ve altında doğan preeklamptikanne bebeklerinin 36.aydaki nörogelişiminin değerlendirmesi ile majör sekel oranını, bilişsel, dil, ince ve kaba motor alanlarında gelişimsel gecikmenin varlığını ve oranını saptamayı amaçladık. 32 hafta ve altında doğan preeklamptik anne bebekleri ve başka nedenlerden dolayı erken doğum yapmış normotansif annelerin prematüre bebekleri; ebeveyn eğitim durumu, doğum öncesi ve doğum öyküsü, morbidite, fiziki gelişim, laboratuar sonuçları, nörolojik muayene ve Bayley nörogelişim testi ile değerlendirildi. 36preeklamptik anne bebeği ve 28 kontrol grubu olmak üzere toplam 64 preterm olgu dâhil edildi. Preeklamptik anne bebekleri ile kontrol grubu arasında erken dönem morbidite ve 36. ay nörogelişim açısından fark saptanmadı. Ancak kontrol grubuna göre beyaz küre ve mutlak nötrofil sayısı, taburculuk kilosu persantili istatistiksel olarak anlamlı derecede daha düşük saptandı.  Kız bebeklerin Bayley dil gelişim skorlarının erkeklere göre daha yüksek olduğu ve 5.dk APGAR skoru ile Bayley indeks skoru arasındapozitif yönde istatistiksel olarak anlamlı korelasyon saptandı. Nörolojik muayenesinde majör nörolojik defisit olan bebeklerin Bayley dil gelişim ve motor skorlarının da anormal olduğu görüldü. Sonuç olarak  preeklampsinin erken doğan bebeklerde prematüreliğin yanında artı bir risk oluşturmadığı görüldü.

Keywords

preeklampsi, nörogelişim, prematürite

Neurodevelopmental Evaluation of Infants of Preeclamptic Mothers at 36 Months Of Age

Abstract

Abstract

Preeclampsia is a disorder of pregnancy leading to preterm birth, maternal and neonatal mortality and morbidity and may cause neurodevelopmental problems. We aimedto evaluate the neurodevelopment of infants of preeclamptic mothers at 36 months ofage, namely majör neurological sequeale, cognitive, language, fine and gross motor abnormalities and their prevalances. Infants of  preeclamptic mothers delivering before 32 weeks of gestation were included into the study. Mothers who delivered before 32 weeks of gestation for another reason constituted the controlgroup. Parental educational status, prenatal and natal history, morbidities, physical development, laboratory results, neurological examinations and Bayley neurodevelopmental scores were compared. There were 36 infants in thestudy group and 28 infants in the control group. There wereno statistically significant differences between both groupregarding early morbidities and 36th month neurodevelopment. In the study group, leukocyte and absolute neutrophil counts and weight at discharge were significantly lower.Bayley developmental scores were higher in the girls andthere was a positive correlation between the 5th minute Apgar scores and Bayley scores. Bayley scores were also lower in infants whose neurological exams were abnormal. Weconcluded that preeclampsia does not pose an additional riskto preterm infants, apart from their own risks.

Keywords

preeclampsia, neurodevelopment, prematurity

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