Research Article
PDF Zotero Mendeley EndNote BibTex Cite

The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study

Year 2019, Volume 11, Issue 3, 392 - 396, 23.10.2019
https://doi.org/10.18521/ktd.521303

Abstract

Aim: Sickle Cell Disease (SCD) patients experience recurrent pain attacks and up to 30% of these become chronic pain. There is known to be a relationship between chronic pain and depression and other psychological problems. Therefore, Sickle Cell Disease patients often experience a series of social and psychiatric problems. The aim of this study to determine the frequency and severity of premenstrual syndrome in women aged ≥18 years with sickle cell disease and to compare these values with healthy women.

Materials and Methods: This case control study was conducted from January 2018 to March 2018. The data were collected using a questionnaire of 21 items and the Premenstrual Syndrome Scale (PMSS). Statistical analysis was performed using SPSS 21 software.

Results: The study included 50 patients aged >18 years who were diagnosed with sickle cell anemia at the University Hospital and control group of 50 subjects with no chronic disease. Premenstrual Syndrome (PMS) according to DSM-5 was determined in 34 (68%) of the case group and 39 (78%) of the control group (p=0,26). Mean depressive effect subscale score was 15.64±6.56 in the sickle cell anemia group while, it was 19.48±6.67 in control group (p=0,05).

Conclusion:

Although PMS frequency and symptom severity in women with SCD were similar with normal population, the depressive effect subscale scores were lower in SCD group. This results’ cause could be attributed to PMS symptoms being perceived as less severe compared to the pain experienced in sickle cell crises.


Amaç: Orak Hücre Hastalığı (OHH)’nda, hastalar tekrarlayan ağrı atakları geçirir ve bunların %30'u kadarında kronik ağrı gelişir. Kronik ağrı ile depresyon ve diğer psikolojik problemler arasında bir ilişki olduğu bilinmektedir. Bu nedenle Orak Hücre Hastalığı hastaları sıklıkla bir dizi sosyal ve psikiyatrik problem yaşayabilirler. Bu çalışmasnın amacı; Orak Hücre Hastalığı olan 18 yaş ve üstü kadınlarda premenstrüel sendromun (PMS) sıklığını ve ciddiyetini belirleyerek sağlıklı kadınlarla karşılaştırmaktır.

Gereç ve Yöntemler: Bir vaka kontrol çalışması olarak Ocak 2018- Mart 2018 arasında yapılmıştır. Veriler 21 maddeden oluşan bir anket formu ve Premenstrüel Sendrom Ölçeği (PMSS) kullanılarak elde edildi.  İstatistiksel analiz SPSS 21 yazılımı kullanılarak yapıldı.

Bulgular: Çalışmaya üniversite hastanesinde orak hücreli anemi tanısı konan ve 18 yaşından büyük 50 hasta ve kronik hastalığı olmayan 50 kişiden oluşan kontrol grubu dahil edildi. DSM-5'e göre PMS; vaka grubunun 34'ünde (%68) ve kontrol grubunun 39'unda (%78) tespit edildi (p = 0,26). Orak hücreli anemi grubunda ortalama depresif etki alt ölçek skoru 15.64 ± 6.56 iken, kontrol grubunda 19.48 ± 6.67 idi (p = 0,05).

Sonuç: OHH'li kadınlarda PMS sıklığı ve semptom şiddeti normal popülasyonla benzer olmasına rağmen, depresif etki alt ölçek puanları SCD grubunda anlamlı olarak daha düşük olmasının nedeni; orak hücre krizlerinde yaşanan ağrıya kıyasla, PMS semptomlarının daha az şiddetli algılanması olabilir.


References

  • 1. Hofmeister S, Bodden S. Premenstrual Syndrome and Premenstrual Dysphoric Disorder. Am Fam Physician. 2016;94(3):236-40.
  • 2. Pinar G, Colak M, Oksuz E. Premenstrual Syndrome in Turkish college students and its effects on life quality. Sex Reprod Healthc. 2011;2(1):21-7.
  • 3. Direkvand-Moghadam A, Sayehmiri K, Delpisheh A, Kaikhavandi S. Epidemiology of Premenstrual Syndrome (PMS)-A Systematic Review and Meta-Analysis Study. J Clin Diagn Res. 2014;8(2):106-9.
  • 4. Alhomoud M, Gosadi I, Wahbi H. Depression among sickle cell anemia patients in the Eastern Province of Saudi Arabia. Saudi Journal of Medicine & Medical Sciences (SJMMS). 2018; 6 (1 ):8-12.
  • 5. Alli NA, Patel M, Alli HD, Bassa F, Coetzee MJ, Davidson A, et al. Recommendations for the management of sickle cell disease in South Africa. S Afr Med J. 2014;104(11):743-51.
  • 6. Guler E, Garipardic M, Dalkiran T, Davutoglu M. Premarital screening test results for beta-thalassemia and sickle cell anemia trait in east Mediterranean region of Turkey. Pediatr Hematol Oncol. 2010;27(8):608-13.
  • 7. Ozer C, Yengil E, Acipayam C, Kokacya M. Relationship between depression, anxiety, quality of life and vasooclusive crisis in adolescents with sickle cell disease. Acta Medica. 2014;30:335-9.
  • 8. Adam SS, Flahiff CM, Kamble S, Telen MJ, Reed SD, De Castro LM. Depression, quality of life, and medical resource utilization in sickle cell disease. Blood Adv. 2017;1(23):1983-92.
  • 9. Clarke DM, Currie KC. Depression, anxiety and their relationship with chronic diseases: a review of the epidemiology, risk and treatment evidence. Med J Aust. 2009;190(7 Suppl):S54-60.
  • 10. Gençdoğan B. Premenstrual sendrom için yeni bir ölçek. Türkiye’de Psikiyatri 2006;8(2):81-7.
  • 11. Erbil N, Bölükbaş N, Tolan S, Uysal F. Determination of the premenstrual syndrome and affecting factors among married women Int J Hum Sci. 2011;8(1):428-38.
  • 12. Canatan D, Kose MR, Ustundag M, Haznedaroglu D, Ozbas S. Hemoglobinopathy control program in Turkey. Community Genet. 2006;9(2):124-6.
  • 13. Ekinci O, Celik T, Unal S, Ozer C. Psychiatric problems in children and adolescents with sickle cell disease, based on parent and teacher reports. Turk J Haematol. 2012;29(3):259-64.
  • 14. Anie KA. Psychological complications in sickle cell disease. Br J Haematol. 2005;129(6):723-9.
  • 15. Morin C, Waring EM. Depression and sickle cell anemia. South Med J. 1981;74(6):766-8.
  • 16. Belgrave FZ, Molock SD. The role of depression in hospital admissions and emergency treatment of patients with sickle cell disease. J Natl Med Assoc. 1991;83(9):777-81.
  • 17. Thompson RJ, Jr., Gil KM, Abrams MR, Phillips G. Stress, coping, and psychological adjustment of adults with sickle cell disease. J Consult Clin Psychol. 1992;60(3):433-40.
  • 18. Tartt K, Appel S, Mann-Jiles V, Demonbreun K, John L. An Integrative Review of Sickle Cell and Depression Int Arch Nurs Health Care 2015;1(020).
  • 19. Hasan SP, Hashmi S, Alhassen M, Lawson W, Castro OJJotNMA. Depression in sickle cell disease. 2003;95(7):533.
  • 20. Molock SD, Belgrave FZJJoh, policy s. Depression and anxiety in patients with sickle cell disease: conceptual and methodological considerations. 1994;5(3-4):39-53.

Orak Hücre Hastalarında Premenstrual Sendrom Semptomlarının Şiddeti- Vaka Kontrol Çalışması

Year 2019, Volume 11, Issue 3, 392 - 396, 23.10.2019
https://doi.org/10.18521/ktd.521303

Abstract

Amaç: Orak Hücre Hastalığı (OHH)’nda, hastalar tekrarlayan ağrı atakları geçirir ve

bunların %30'u kadarında kronik ağrı gelişir. Kronik ağrı ile depresyon ve diğer

psikolojik problemler arasında bir ilişki olduğu bilinmektedir. Bu nedenle Orak Hücre

Hastalığı hastaları sıklıkla bir dizi sosyal ve psikiyatrik problem yaşayabilirler. Bu

çalışmasının amacı; Orak Hücre Hastalığı olan 18 yaş ve üstü kadınlarda premenstrüel

sendromun (PMS) sıklığını ve ciddiyetini belirleyerek sağlıklı kadınlarla

karşılaştırmaktır.

Gereç ve Yöntem: Bir vaka kontrol çalışması olarak Ocak 2018-Mart 2018 arasında

yapılmıştır. Veriler 21 maddeden oluşan bir anket formu ve Premenstrüel Sendrom

Ölçeği (PMSS) kullanılarak elde edildi. İstatistiksel analiz SPSS 21 yazılımı

kullanılarak yapıldı.

Bulgular: Çalışmaya üniversite hastanesinde orak hücreli anemi tanısı konan ve 18

yaşından büyük 50 hasta ve kronik hastalığı olmayan 50 kişiden oluşan kontrol grubu

dahil edildi. DSM-5'e göre PMS; vaka grubunun 34'ünde (%68) ve kontrol grubunun

39'unda (%78) tespit edildi (p = 0,26). Orak hücreli anemi grubunda ortalama depresif

etki alt ölçek skoru 15.64 ± 6.56 iken, kontrol grubunda 19.48 ± 6.67 idi (p = 0,05).

Sonuç: OHH'li kadınlarda PMS sıklığı ve semptom şiddeti normal popülasyonla benzer

olmasına rağmen, depresif etki alt ölçek puanları SCD grubunda anlamlı olarak daha

düşük olmasının nedeni; orak hücre krizlerinde yaşanan ağrıya kıyasla, PMS

semptomlarının daha az şiddetli algılanması olabilir.

References

  • 1. Hofmeister S, Bodden S. Premenstrual Syndrome and Premenstrual Dysphoric Disorder. Am Fam Physician. 2016;94(3):236-40.
  • 2. Pinar G, Colak M, Oksuz E. Premenstrual Syndrome in Turkish college students and its effects on life quality. Sex Reprod Healthc. 2011;2(1):21-7.
  • 3. Direkvand-Moghadam A, Sayehmiri K, Delpisheh A, Kaikhavandi S. Epidemiology of Premenstrual Syndrome (PMS)-A Systematic Review and Meta-Analysis Study. J Clin Diagn Res. 2014;8(2):106-9.
  • 4. Alhomoud M, Gosadi I, Wahbi H. Depression among sickle cell anemia patients in the Eastern Province of Saudi Arabia. Saudi Journal of Medicine & Medical Sciences (SJMMS). 2018; 6 (1 ):8-12.
  • 5. Alli NA, Patel M, Alli HD, Bassa F, Coetzee MJ, Davidson A, et al. Recommendations for the management of sickle cell disease in South Africa. S Afr Med J. 2014;104(11):743-51.
  • 6. Guler E, Garipardic M, Dalkiran T, Davutoglu M. Premarital screening test results for beta-thalassemia and sickle cell anemia trait in east Mediterranean region of Turkey. Pediatr Hematol Oncol. 2010;27(8):608-13.
  • 7. Ozer C, Yengil E, Acipayam C, Kokacya M. Relationship between depression, anxiety, quality of life and vasooclusive crisis in adolescents with sickle cell disease. Acta Medica. 2014;30:335-9.
  • 8. Adam SS, Flahiff CM, Kamble S, Telen MJ, Reed SD, De Castro LM. Depression, quality of life, and medical resource utilization in sickle cell disease. Blood Adv. 2017;1(23):1983-92.
  • 9. Clarke DM, Currie KC. Depression, anxiety and their relationship with chronic diseases: a review of the epidemiology, risk and treatment evidence. Med J Aust. 2009;190(7 Suppl):S54-60.
  • 10. Gençdoğan B. Premenstrual sendrom için yeni bir ölçek. Türkiye’de Psikiyatri 2006;8(2):81-7.
  • 11. Erbil N, Bölükbaş N, Tolan S, Uysal F. Determination of the premenstrual syndrome and affecting factors among married women Int J Hum Sci. 2011;8(1):428-38.
  • 12. Canatan D, Kose MR, Ustundag M, Haznedaroglu D, Ozbas S. Hemoglobinopathy control program in Turkey. Community Genet. 2006;9(2):124-6.
  • 13. Ekinci O, Celik T, Unal S, Ozer C. Psychiatric problems in children and adolescents with sickle cell disease, based on parent and teacher reports. Turk J Haematol. 2012;29(3):259-64.
  • 14. Anie KA. Psychological complications in sickle cell disease. Br J Haematol. 2005;129(6):723-9.
  • 15. Morin C, Waring EM. Depression and sickle cell anemia. South Med J. 1981;74(6):766-8.
  • 16. Belgrave FZ, Molock SD. The role of depression in hospital admissions and emergency treatment of patients with sickle cell disease. J Natl Med Assoc. 1991;83(9):777-81.
  • 17. Thompson RJ, Jr., Gil KM, Abrams MR, Phillips G. Stress, coping, and psychological adjustment of adults with sickle cell disease. J Consult Clin Psychol. 1992;60(3):433-40.
  • 18. Tartt K, Appel S, Mann-Jiles V, Demonbreun K, John L. An Integrative Review of Sickle Cell and Depression Int Arch Nurs Health Care 2015;1(020).
  • 19. Hasan SP, Hashmi S, Alhassen M, Lawson W, Castro OJJotNMA. Depression in sickle cell disease. 2003;95(7):533.
  • 20. Molock SD, Belgrave FZJJoh, policy s. Depression and anxiety in patients with sickle cell disease: conceptual and methodological considerations. 1994;5(3-4):39-53.

Details

Primary Language English
Subjects Health Care Sciences and Services
Published Date Ekim 2019
Journal Section Articles
Authors

Pinar DONER GUNER (Primary Author)
HATAY MUSTAFA KEMAL ÜNİVERSİTESİ, TAYFUR ATA SÖKMEN TIP FAKÜLTESİ
0000-0002-5245-5299
Türkiye


Sabahat USLUSOY This is me
HATAY MUSTAFA KEMAL ÜNİVERSİTESİ, TAYFUR ATA SÖKMEN TIP FAKÜLTESİ


Gul ILHAN
HATAY MUSTAFA KEMAL ÜNİVERSİTESİ, TAYFUR ATA SÖKMEN TIP FAKÜLTESİ
0000-0003-1616-6358


Sumeyya Havva KOKACYA This is me
HATAY MUSTAFA KEMAL ÜNİVERSİTESİ, TAYFUR ATA SÖKMEN TIP FAKÜLTESİ


Emre DİRİCAN
HATAY MUSTAFA KEMAL ÜNİVERSİTESİ, TAYFUR ATA SÖKMEN TIP FAKÜLTESİ
0000-0003-3550-1326


Mehmet Hanifi KOKACYA
MUSTAFA KEMAL ÜNİVERSİTESİ, TAYFUR ATA SÖKMEN TIP FAKÜLTESİ


Erhan YENGİL
MUSTAFA KEMAL ÜNİVERSİTESİ, TAYFUR ATA SÖKMEN TIP FAKÜLTESİ
0000-0002-4198-4873


Cahit OZER
MUSTAFA KEMAL ÜNİVERSİTESİ, TAYFUR ATA SÖKMEN TIP FAKÜLTESİ

Publication Date October 23, 2019
Published in Issue Year 2019, Volume 11, Issue 3

Cite

Bibtex @research article { ktd521303, journal = {Konuralp Medical Journal}, issn = {1309-3878}, eissn = {1309-3878}, address = {}, publisher = {Duzce University}, year = {2019}, volume = {11}, pages = {392 - 396}, doi = {10.18521/ktd.521303}, title = {The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study}, key = {cite}, author = {Doner Guner, Pinar and Uslusoy, Sabahat and Ilhan, Gul and Kokacya, Sumeyya Havva and Dirican, Emre and Kokacya, Mehmet Hanifi and Yengil, Erhan and Ozer, Cahit} }
APA Doner Guner, P. , Uslusoy, S. , Ilhan, G. , Kokacya, S. H. , Dirican, E. , Kokacya, M. H. , Yengil, E. & Ozer, C. (2019). The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study . Konuralp Medical Journal , 11 (3) , 392-396 . DOI: 10.18521/ktd.521303
MLA Doner Guner, P. , Uslusoy, S. , Ilhan, G. , Kokacya, S. H. , Dirican, E. , Kokacya, M. H. , Yengil, E. , Ozer, C. "The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study" . Konuralp Medical Journal 11 (2019 ): 392-396 <https://dergipark.org.tr/en/pub/ktd/issue/49753/521303>
Chicago Doner Guner, P. , Uslusoy, S. , Ilhan, G. , Kokacya, S. H. , Dirican, E. , Kokacya, M. H. , Yengil, E. , Ozer, C. "The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study". Konuralp Medical Journal 11 (2019 ): 392-396
RIS TY - JOUR T1 - The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study AU - Pinar Doner Guner , Sabahat Uslusoy , Gul Ilhan , Sumeyya Havva Kokacya , Emre Dirican , Mehmet Hanifi Kokacya , Erhan Yengil , Cahit Ozer Y1 - 2019 PY - 2019 N1 - doi: 10.18521/ktd.521303 DO - 10.18521/ktd.521303 T2 - Konuralp Medical Journal JF - Journal JO - JOR SP - 392 EP - 396 VL - 11 IS - 3 SN - 1309-3878-1309-3878 M3 - doi: 10.18521/ktd.521303 UR - https://doi.org/10.18521/ktd.521303 Y2 - 2019 ER -
EndNote %0 Konuralp Medical Journal The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study %A Pinar Doner Guner , Sabahat Uslusoy , Gul Ilhan , Sumeyya Havva Kokacya , Emre Dirican , Mehmet Hanifi Kokacya , Erhan Yengil , Cahit Ozer %T The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study %D 2019 %J Konuralp Medical Journal %P 1309-3878-1309-3878 %V 11 %N 3 %R doi: 10.18521/ktd.521303 %U 10.18521/ktd.521303
ISNAD Doner Guner, Pinar , Uslusoy, Sabahat , Ilhan, Gul , Kokacya, Sumeyya Havva , Dirican, Emre , Kokacya, Mehmet Hanifi , Yengil, Erhan , Ozer, Cahit . "The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study". Konuralp Medical Journal 11 / 3 (October 2019): 392-396 . https://doi.org/10.18521/ktd.521303
AMA Doner Guner P. , Uslusoy S. , Ilhan G. , Kokacya S. H. , Dirican E. , Kokacya M. H. , Yengil E. , Ozer C. The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study. Konuralp Medical Journal. 2019; 11(3): 392-396.
Vancouver Doner Guner P. , Uslusoy S. , Ilhan G. , Kokacya S. H. , Dirican E. , Kokacya M. H. , Yengil E. , Ozer C. The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study. Konuralp Medical Journal. 2019; 11(3): 392-396.
IEEE P. Doner Guner , S. Uslusoy , G. Ilhan , S. H. Kokacya , E. Dirican , M. H. Kokacya , E. Yengil and C. Ozer , "The Severity of Premenstrual Syndrome Symptoms in Sickle Cell Disease Patients: A Case- Control Study", Konuralp Medical Journal, vol. 11, no. 3, pp. 392-396, Oct. 2019, doi:10.18521/ktd.521303