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            <front>

                <journal-meta>
                                                                <journal-id>kırıkkale uni med j</journal-id>
            <journal-title-group>
                                                                                    <journal-title>The Journal of Kırıkkale University Faculty of Medicine</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2148-9645</issn>
                                                                                            <publisher>
                    <publisher-name>Kirikkale University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.24938/kutfd.1804956</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Health Services and Systems (Other)</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Sağlık Hizmetleri ve Sistemleri (Diğer)</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <trans-title-group xml:lang="tr">
                                    <trans-title>HALP Skorunun Solunum Problemiyle Yatışı Yapılan Çok Yaşlı Hastalarda Hastane İçi Mortalite Riskinin Tahminindeki Rolü</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>THE PERFORMANCE OF HALP SCORE IN PREDICTING IN-HOSPITAL MORTALITY RISK AMONG VERY ELDERLY PATIENTS WITH RESPIRATORY-RELATED HOSPITALIZATION</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-2459-8022</contrib-id>
                                                                <name>
                                    <surname>Akbay</surname>
                                    <given-names>Makbule Özlem</given-names>
                                </name>
                                                                    <aff>Department of Chest Diseases, University of Health Sciences, Istanbul Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, ISTANBUL, TÜRKİYE</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-9008-4508</contrib-id>
                                                                <name>
                                    <surname>Ernam</surname>
                                    <given-names>Dilek</given-names>
                                </name>
                                                                    <aff>Department of Chest Diseases, University of Health Sciences, Istanbul Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, ISTANBUL, TÜRKİYE</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20251225">
                    <day>12</day>
                    <month>25</month>
                    <year>2025</year>
                </pub-date>
                                        <volume>27</volume>
                                        <issue>3</issue>
                                        <fpage>378</fpage>
                                        <lpage>385</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20251016">
                        <day>10</day>
                        <month>16</month>
                        <year>2025</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20251024">
                        <day>10</day>
                        <month>24</month>
                        <year>2025</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1999, The Journal of Kırıkkale University Faculty of Medicine</copyright-statement>
                    <copyright-year>1999</copyright-year>
                    <copyright-holder>The Journal of Kırıkkale University Faculty of Medicine</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="tr">
                            <p>Amaç: Bu çalışmada hemoglobin ve albümin düzeyleri ve lenfosit ve trombosit sayımını birlikte içeren yeni bir skor olarak HALP skorunun solunum problemiyle yatışı yapılan çok yaşlı hastalarda hastane içi mortalite riskinin tahminindeki rolünün incelenmesi amaçlandı. Gereç ve Yöntemler: Bu tek-merkezli retrospektif kohort çalışmasına solunum problemi ile yatışı yapılan toplam 2011 çok yaşlı (80 yaş üzeri) hasta dahil edildi. Hospitalizasyon nedeni, komorbiditeler, yatışın ilk günü yapılan tam kan sayımı ve biyokimya testi sonuçları, hastanede kalış süresi (HKS) ve hastane içi mortalite verileri kaydedildi. Hastane içi mortalitenin belirleyicileri tek-değişkenli ve çok-değişkenli Cox regresyon analizi ile saptandı. HALP skorunun hastane içi mortaliteyi tahmin etmedeki performansı ROC eğrisi analizi ile belirlendi. Bulgular: Medyan hasta yaşı 83 yıl (80-108 yaş aralığında) olup, çalışma popülasyonundaki erkek hastaların oranı %51,6 idi. Hastane içi mortalite oranı %7 olarak bulundu. Çok-değişkenli analizde, düşük HALP skoru (HR 0,693, %95 GA: 0,549-0,875, p=0,002), erkek cinsiyet (HR 0,654, %95 GA: 0,453-0,945, p=0,024) ve yüksek C-reaktif protein (CRP) değeri (HR 1,004, %95 GA: 1,002-1,006, p</p></trans-abstract>
                                                                                                                                    <abstract><p>Objective: This study aimed to investigate the performance of the novel score combining hemoglobin and albumin levels and lymphocyte and platelet count (HALP) in predicting in-hospital mortality risk in very elderly patients with respiratory-related hospitalization. Material and Methods: A total of 2011 very elderly (over 80 years) patients with respiratory-related hospitalization were included in this single-center retrospective cohort study. Reason for hospitalization, comorbidities, complete blood count and biochemistry findings on the first day of hospital admission, length of hospital stay (LOS), and in-hospital mortality were recorded. Factors predicting in-hospital mortality risk were analyzed via the univariate and multivariate Cox regression analyses. The ROC curve analysis was performed to determine the performance of HALP score in predicting the in-hospital mortality risk. Results: The median age was 83 years (range, 80 to 108 years) and males comprised 51.6% of the study population. The in-hospital mortality rate was 7%. The lower HALP score (HR 0.693, 95% CI: 0.549 to 0.875, p=0.002), male gender (HR 0.654, 95% CI: 0.453 to 0.945, p=0.024), and higher C-reactive protein (CRP) values (HR 1.004, 95% CI: 1.002 to 1.006, p</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>HALP score</kwd>
                                                    <kwd>  respiratory-related hospitalization</kwd>
                                                    <kwd>  in-hospital mortality</kwd>
                                                    <kwd>  very elderly patients</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="tr">
                                                    <kwd>HALP skoru</kwd>
                                                    <kwd>  solunum problemi ile hospitalizasyon</kwd>
                                                    <kwd>  hastane içi mortalite</kwd>
                                                    <kwd>  çok yaşlı hastalar</kwd>
                                            </kwd-group>
                                                                                                                                    <funding-group specific-use="FundRef">
                    <award-group>
                                                    <funding-source>
                                <named-content content-type="funder_name">No financial support was received from any institution or person.</named-content>
                            </funding-source>
                                                                    </award-group>
                </funding-group>
                                </article-meta>
    </front>
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