Abstract
Fibroadenoma is a gruop of tumor with low cellularitied fibrous stroma without cytologic atypia. Fibroadenomas generally seen on young women. They are movable and macroscopic
appearance is characteristical and diagnostic. On the other hand ductal carcinoma in situ(DCIS) is a heterogenous group of lesion on pathological and biologic performance which is limited into mammary ductus and characterized by malign epithelial cell proliferation. 28 years old woman patient with presenting a palpable mass on right mammary 12 o'clock side complaint in polyclinic was applied ultrasonography and diagnosed a 2,5x2cm sized wellcircumscribed lesion which is compatible with fibroadenoma. This mass was removed surgically because of patient request. Removed material was reported as ductal carcinoma in situ located into fibroadenoma. Another fibroadenoma on lower inner quadrant was detected by ultrasonography on postoperative period. Any pathological finding compatible with metastasis was not found on routine tests. According to recently articles it is suggested to excise all fibroadenomas separately patient age and other indicators. Even if we are sure about fibroadenomas are "benign", we should detect of patients having any new "suspicious" symptom in regular periods by diagnostic tests suitable for patient age.
Keywords
References
- Sakorafas GH, Farley DR, Peros G. Recent advances and current controversies in the management of DCIS of the breast. Cancer Treat Rev 2008. doi: 10.1016/j. ctrv. 2008.03.001 (PubMed PMID: 18490111).
- Diaz NM, Palmer JO, Mc Divitt RW. Carcinoma arising with in fibroadenomas of the breast: a clinico pathologic study of 105 patients. Am J Clin Pathol. 1991; 95: 614-22 (PubMed PMID: 1850948).
- Ozzello L, Gump FE. The management of patient swith carcinomas in fibroadenoma tous tumors of the breast. Surg Gynecol Obstet. 1985; 160: 99-104. (PubMed PMID: 2982218).
- Buzanowsky- Konarky K, Harrison EG, Payne WS. Lobular carcinoma arising in fibroadenoma of the breast. Cancer. 1975; 35: 450-56. (PubMed PMID: 1111920).
- Pick PW, Iossifides IA. Occurrence of breast carcinoma within a fibroadenoma: a review. Arch Pathol Lab Med. 1984; 108: 590-96 (PubMed PMID: 6329129).
- Mc Divitt RW, Stewart FD, Farrow JH. Breast carcinoma arising in solitary fibroadenomas. Surg Gynecol Obstet. 1976; 125: 572-76 (PubMed PMID: 6035784).
- Fondo EY, Rosen PP, Fracchia AA, Urban JA. The problem of carcinoma developing in a fibroadenoma. Cancer. 1979; 43: 563-67. (PubMed PMID: 217522).
Abstract
Fibroadenom sitolojik atipi olmaksızın düşük sellülarite gösteren fibröz stromadan oluşan tümörlere verilen isimdir. Bu tümörler genellikle genç kadınlarda görülürler. Kolayca hareket ettirilebilen, mobil kitlelerdir, makroskopik görünümleri genellikle karakteristik ve tanı koydurucudur. Duktal karsinoma in situ (DKİS) ise, meme duktusuna sınırlı malign epitelyal hücre proliferasyonu ile karakterize, patolojik ve biyolojik davranış özellikleri ile heterojen bir lezyon grubudur.
Polikliniğimize sağ meme saat 12 hizasında ele gelen kitle şikâyeti ile başvuran 28 yaşında bayan hastada çekilen ultrasonografide 2,5x2cm boyutunda düzgün sınırlı fibroadenom görüntüsü ile uyumlu kitle hastanın isteği ile çıkarıldı. Patoloji sonucu fibroadenom içine yerleşmiş duktal karsinoma in situ olarak yorumlandı. Hastanın postoperatif dönemde çekilen ultrasonografisinde sol alt kadranda da fibroadenoma rastlandı. Taramalarında metastatazı düşündürecek patolojik bulgu yok idi.
Son yapılan çalışmalarda, hastanın yaşından veya diğer sorunlarından bağımsız olarak tüm fibroadenomların çıkartılması önerilmiştir. Fibroadenomların “iyi huylu” olduğundan emin olsak bile belirli peridyodlarla “şüpheli” herhangi bir yeni bulgu taşıyıp taşımadığına hastanın yaşına uygun tarama yöntemleriyle bakmak zorundayız.Keywords
References
- Sakorafas GH, Farley DR, Peros G. Recent advances and current controversies in the management of DCIS of the breast. Cancer Treat Rev 2008. doi: 10.1016/j. ctrv. 2008.03.001 (PubMed PMID: 18490111).
- Diaz NM, Palmer JO, Mc Divitt RW. Carcinoma arising with in fibroadenomas of the breast: a clinico pathologic study of 105 patients. Am J Clin Pathol. 1991; 95: 614-22 (PubMed PMID: 1850948).
- Ozzello L, Gump FE. The management of patient swith carcinomas in fibroadenoma tous tumors of the breast. Surg Gynecol Obstet. 1985; 160: 99-104. (PubMed PMID: 2982218).
- Buzanowsky- Konarky K, Harrison EG, Payne WS. Lobular carcinoma arising in fibroadenoma of the breast. Cancer. 1975; 35: 450-56. (PubMed PMID: 1111920).
- Pick PW, Iossifides IA. Occurrence of breast carcinoma within a fibroadenoma: a review. Arch Pathol Lab Med. 1984; 108: 590-96 (PubMed PMID: 6329129).
- Mc Divitt RW, Stewart FD, Farrow JH. Breast carcinoma arising in solitary fibroadenomas. Surg Gynecol Obstet. 1976; 125: 572-76 (PubMed PMID: 6035784).
- Fondo EY, Rosen PP, Fracchia AA, Urban JA. The problem of carcinoma developing in a fibroadenoma. Cancer. 1979; 43: 563-67. (PubMed PMID: 217522).
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Articles |
| Authors | |
| Publication Date | January 4, 2016 |
| Submission Date | January 4, 2016 |
| Published in Issue | Year 2014 Volume: 16 Issue: 2 |
Cite
This Journal is a Publication of Kırıkkale University Faculty of Medicine.