KORPUS KALLOSUMUN DİFÜZYON AĞIRLIKLI VE KONVANSİYONEL MANYETİK REZONANS GÖRÜNTÜLEME İLE YAŞA GÖRE DEĞERLENDİRİLMESİ

Year 2018, Volume: 20 Issue: 1, 51 - 61, 30.04.2018

M. Yasemin Karadeniz Bilgili , Rabia Karasu

https://doi.org/10.24938/kutfd.346275

Cited By: 1

Abstract

Amaç: Difüzyon ağırlıklı görüntüleme,
beyin dokusunun canlılığı hakkında fikir veren önemli bir yöntem olup kuvvetli
manyetik alan gradientleri kullanılmaktadır. Buna bağlı olarak difüzyon
ağırlıklı görüntüleme tekniği su moleküllerinin mikroskopik hareketlerindeki
değişikliklerin saptanmasını mümkün kılmaktadır. Çalışmamızda, difüzyon
ağırlıklı görüntüleme ile su moleküllerinin aksonlar boyunca olan
hareketlerinden yararlanarak elde edilen Apparent Diffusion Coefficient (ADC)
değişikliklerinin yaşa göre değişiminin değerlendirilmesi amaçlanmıştır.

Gereç ve Yöntem: Çalışmamıza dahil edilen 94 olgunun
ADC haritaları üzerinden korpus kallosumun farklı bölgelerinden ADC değerleri
değerlendirildi.

Bulgular: ADC değerinin minimum ve maksimum
değerleri 0.589-0.819 mm²/sn x 10^-³, ortalama ADC değeri ise 0.735 ±
0.043 mm²/sn x 10^-³ olarak bulunmuştur. Çalışmamızda yaş arttıkça,
korpus kallosumun ortalama ADC değerlerinde istatistiksel olarak belirgin
derecede artış bulunmuştur (p <0.01).

Sonuç: İlerleyen
yaşla beyaz cevherdeki suyun difüzyon kabiliyetindeki artış yönündeki teorimiz,
verilerimizdeki istatistiksel olarak anlamlı sonuçlarla desteklenmiştir. Yani
suyun korpus kallosumda difüzyon kabiliyetinin yaş ilerledikçe arttığı saptanmıştır. Sonuç olarak, fonksiyonel bir görüntüleme yöntemi olan
difüzyon ağırlıklı görüntüleme, yaşlanmaya bağlı değişiklikleri sayısal olarak
da ortaya koyabilen bir yöntemdir.

Keywords

korpus kallosum, Difüzyon ağırlıklı görüntüleme, Apparent Diffusion Coefficient, yaş

Evaluation of Corpus Callosum by Means of Diffusion-Weighted and Conventional Magnetic Resonance Imaging According to the Age

Abstract

Objective: Evaluation of corpus callosum
by means of diffusion-weighted and conventional magnetic resonance imaging
according to the age Diffusion-weighted
imaging (DWI) is a significant method
that gives an idea as to the vitality of the brain tissue. DWI is affected
from the movements of the
patient at a minimum with its strong magnetic field gradients and is extraordinarily sensitive in reflection
of the changes in the microscopic translational
activities of the water molecules.
Objective of our study is to evaluate by means of diffusion-weighted imaging the Apparent
Diffusion Coefficient (ADC) changes by
aging which are obtained using the activities of the water
molecules throughout axons.

Material and Methods: ADC measurement of corpus callosum
at different parts has been studied in 94 patient

Results: Minimum
and maximum values of the ADC
value were found as 0.589-0.819 mm²/sn x 10^-³ while the average ADC value was found as 0.735 ± 0.043 mm²/sn x 10^-³. Our study has revealed a distinctive
statistical increase in the average ADC
values of corpus callosum in line with
aging (p <0.01).

Conclusion: Our theory as to the increase in the diffusion capability of the water in the white substance along with aging has been substantiated with the statistically significant results in our data. In other words, it has been
detected that diffusion capability of the water in corpus callosum increases
along with aging. In conclusion, it is beyond doubt that the diffusion-weighted
MRI which is a new functional imaging method in clinic application will be
improved even better in the years to come and can be used in a more widespread
manner.

Keywords

Diffusion-weighted imaging, Apparent Diffusion Coefficient, corpus callosum, age

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