Mehmet Akif Ersoy University Journal of Health Sciences Institute 2148-2837 Burdur Mehmet Akif Ersoy University 10.24998/maeusabed.1818696 Veterinary Medicine Veteriner Hekimlik Evaluation of Some Serum Acute Phase Proteins in Goats with Infectious Keratoconjunctivitis in Siirt Province Siirt İlinde Enfeksiyöz Keratokonjonktivitli Keçilerde Bazı Serum Akut Faz Proteinlerinin Değerlendirilmesi https://orcid.org/0000-0001-9210-4744 Erdeğer Özlem SİİRT ÜNİVERSİTESİ https://orcid.org/0000-0002-1164-3429 Şahin Tekin SİİRT ÜNİVERSİTESİ https://orcid.org/0000-0003-4804-6502 Akgül Gülşah SİİRT ÜNİVERSİTESİ https://orcid.org/0000-0002-9365-9925 Akgül Mustafa Barış SİİRT ÜNİVERSİTESİ https://orcid.org/0000-0001-6799-1716 Baldaz Vedat SİİRT ÜNİVERSİTESİ https://orcid.org/0000-0003-4914-8578 Ercan Kerem SİİRT ÜNİVERSİTESİ https://orcid.org/0000-0001-6138-7163 Kahya Demirbilek Serpil Bursa Uludağ Üniversitesi https://orcid.org/0000-0003-2883-2338 Yildiz Merve ULUDAĞ ÜNİVERSİTESİ 04 21 2026 2026 11 06 2025 03 24 2026 Copyright © 2013, Mehmet Akif Ersoy University Journal of Health Sciences Institute 2013 Mehmet Akif Ersoy University Journal of Health Sciences Institute

The aim of this study was to evaluate certain acute phase proteins in goats with infectious keratoconjunctivitis. For this purpose, a total of 75 goats were used—50 with IKC and 25 healthy controls. After routine general and ophthalmic examinations (body temperature, pulse and respiration rate, lymph node palpation, abdominal palpation, and lung auscultation), eye swabs were collected from goats diagnosed with IKC. A total of 15 different bacteria were isolated from the eye swabs. The serum was separated from the blood samples taken from the goats included in the study and stored at -20 °C until analysis. Serum levels of amyloid A, C-reactive protein, ceruloplasmin, and fibrinogen were measured using commercial ELISA kits. Significant increases in acute phase protein levels were observed in the IKC group. Based on the results, it was suggested that acute phase proteins may be useful indicators for the diagnosis and monitoring of inflammation developing during IKC.

Bu çalışmanın amacı infeksiyöz keratokonjuktivit görülen keçilerde bazı akut faz proteinlerinin değerlendirilmesidir. Bu amaçla 50’si İKC’li ve 25’i sağlıklı olmak üzere toplam 75 keçi kullanıldı. Çalışmaya dahil edilen hayvanlara rutin genel muayene (beden sıcaklığı, nabız ve solunum sayısı, lenf düğümleri muayenesi, abdominal palpasyon, akciğer oskültasyonu) ve göz muayenesi yapıldıktan sonra, İKC olduğu belirlenen keçilerden göz svabı alındı. Alınan göz svaplarından toplam 15 farklı bakteri izole edildi. Çalışmaya dahil edilen keçilerden alınan kan örneklerinin serumları ayrıldı ve analiz edilinceye kadar -20 °C’de saklandı. Serum amiloid A, C-reaktif protein, seruloplazmin ve fibrinojenin serum seviyeleri ticari ELISA kitleriyle ölçüldü. İKC grubunda akut faz proteinlerinin düzeylerinde önemli artışlar gözlendi. Elde edilen sonuçlar doğrultusunda, İKC sırasında gelişen inflamasyonun tanı ve takibinde akut faz proteinlerinin önemli olabileceği düşünülmektedir.

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