In this study.,tetanus antitoxin titres were measured in Sivas in certain age groups. In Turkey, childhood primary vaccination program is in effect against tetanus for many years. However, in spite of this vaccination program, deaths still occur from neonatal tetanus and tetanus in Turkey. On this basis, immunity against tetanus was examined in randomly sampled 400 subjects with ages ranging from 1 day to 85 years. Tetanus antitoxin titres were determined by Turkey Red Blood Cells Passive Hemagglutination (TRBC-HA) technique. The highest number of unprotected people against tetanus were found among subjects above 30 years of age (75%) and most of them were female (81.1 %).