<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="research-article"        dtd-version="1.4">
            <front>

                <journal-meta>
                                                                <journal-id>marmara med j</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Marmara Medical Journal</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">1019-1941</issn>
                                        <issn pub-type="epub">1309-9469</issn>
                                                                                            <publisher>
                    <publisher-name>Marmara University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.5472/marumj.570917</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Clinical Sciences</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Klinik Tıp Bilimleri</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                                                            <article-title>Successful intrauterine treatment of nonimmune hydrops fetalis due to pericardial tumor</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Corbacıoglu Esmer</surname>
                                    <given-names>Aytul</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Bornaun</surname>
                                    <given-names>Helen</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Turan Bakırcı</surname>
                                    <given-names>İsil</given-names>
                                </name>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20190531">
                    <day>05</day>
                    <month>31</month>
                    <year>2019</year>
                </pub-date>
                                        <volume>32</volume>
                                        <issue>2</issue>
                                        <fpage>90</fpage>
                                        <lpage>93</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20190115">
                        <day>01</day>
                        <month>15</month>
                        <year>2019</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20190331">
                        <day>03</day>
                        <month>31</month>
                        <year>2019</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1988, Marmara Medical Journal</copyright-statement>
                    <copyright-year>1988</copyright-year>
                    <copyright-holder>Marmara Medical Journal</copyright-holder>
                </permissions>
            
                                                                                                                        <abstract><p>The prenatal diagnosis of pericardial tumor is extremely rare.It may have serious consequences such as massive pericardialeffusion, cardiac tamponade, hydrops fetalis and fetal demise.We present a case of nonimmune hydrops fetalis secondaryto pericardial mass which was successfully treated in uteroby serial pericardiocentesis. Also, we present a review of theliterature regarding the intrauterine interventions performedin pericardial tumor cases. At 24 weeks’ gestation ascites,diffuse subcutaneous edema at the thorax and abdomen, scalpedema and two masses within severe pericardial effusion weredetected. After the pericardiocentesis performed at 25, 28 and29 weeks’ gestation, ascites and scalp edema resolved, and thepericardial effusion regressed gradually. The size of masses didnot change throughout the gestation. After the infant was bornat 37 weeks’ gestation, the masses shrunk spontaneously withinfive months</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Pericardial tumor</kwd>
                                                    <kwd>  Pericardiocentesis</kwd>
                                                    <kwd>  Intrauterine treatment</kwd>
                                                    <kwd>  Nonimmune hydrops fetalis</kwd>
                                                    <kwd>  Pericardial effusion</kwd>
                                            </kwd-group>
                            
                                                                                                                                                    </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">1. Holley DG, Martin GR, Brenner JI. Diagnosis and management
of fetal cardiac tumors: a multicenter experience and review
of published reports. J Am Coll Cardiol 1995;26:516-20. doi:
10.1016/0735-1097(95)80031-B.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">2. Isaacs H. Fetal and neonatal cardiac tumors. Pediatr Cardiol
2004;25:252-73. doi:10.1007/s00246.003.0590-4.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">3. Bruch SW, Adzick NS, Reiss R, et al. Prenatal therapy for
pericardial teratomas. J Pediatr Surg 1997;32:1113-5. doi:
10.1016/ S0022-3468(97)90410-3.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">4. Sklansky M, Greenberg M, Lucas V, et al. Intrapericardial
teratoma in a twin fetus: Diagnosis and management.
Obstet Gynecol 1997;89:807-9. doi:10.1016/S0029-
7844(97)00031-8.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">5. Laquay N, Ghazouani S, Vaccaroni L, et al. Intrapericardial
teratoma in newborn babies. Eur J Cardiothorac Surg
2003;23:642-44. doi:10.1016/S1010-7940(02)00861-8.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">6. Tollens T, Casselman F, Devligrt H, et al. Fetal cardiac
tamponade due to an intrapericardial teratoma. Ann Thorac
Surg 1998;66:559-60. doi:10.1016/S0003-4975(98)00508-6.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">7. Grebille AG, Mitanchez D, Benachi A, et al. Pericardial
teratoma complicated by hydrops: successful fetal therapy
by thoracoamniotic shunting. Prenat Diagn 2003,23: 735-9.
doi: 10.1002/pd.698.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">8. Rychik J, Khalek N, Gaynor JW, et al. Fetal intrapericardial
teratoma: natural history and management including
successful in utero surgery. Am J Obstet Gynecol 2016;215:
780. e1-e7. doi:10.1016/j. ajog.2016.08.010.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">9. Bader R, Hornberger LK, Nijmeh LJ, et al. Fetal pericardial
teratoma: presentation of two cases and review of the literature.
Am J Perinatol 2006;23:53-8. doi: 10.1055/s—2005-923433.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">10. Devliger R, Hindryckx A, Van Miegham T, et al. Therapy
for foetal pericardial tumours: Survival following in
utero shunting, and literature review. Fetal Diagn Ther
2009;25:407-12. doi:10.1159/000236156.</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">11. Riggs T, Sholl JS, Ilbawi M, et al. In utero diagnosis of
pericardial tumor with successful surgical repair. Pediatr
Cardiol 1984;5:23-6.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">12. Paw PT, Jamieson SW. Surgical management of
intraperciardial teratoma diagnosed in utero. Ann Thorac
Surg 1997;64:552-4. doi:10.1016/S0003-4975(97)00585-7.</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">13. Todros T, Gaglioti P, Presbitero P. Management of a fetus with
intrapericardial teratoma diagnosed in utero. J Ultrasound
Med 1991;10:287-90. doi: 10.7863/jum.1991.10.5.287.</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">14. Perez-Aytes A, Sanchis N, Barbal A, et al. Non-immunological
hydrops fetalis and intrapericardial teratoma: Case report
and review. Prenat Diagn 1995;15:859-63. doi:10.1002/
pd.970150912.</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">15. Sepulveda W, Gomez E, Gutierrez J. Intrapericardial
teratoma. Ultrasound Obstet Gynecol 2000;15:547-8.
doi:10.1046/j.1469-0705.2000.00144.x</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">16. Fujimori K, Honda S, Akutsu H, et al. Prenatal diagnosis of
intrapericardial teratoma: a case report. J Obstet Gynaecol Res
1999;25:133-6. doi:10.1111/j.1447-0756.1999.tb01135.x.</mixed-citation>
                    </ref>
                                    <ref id="ref17">
                        <label>17</label>
                        <mixed-citation publication-type="journal">17. Sydorak RM, Kelly T, Feldstein VA, et al. Prenatal resection
of o fetal pericardial teratoma. Fetal Diagn Ther 2002;17:281-
5. doi: 10.1159/000063180.</mixed-citation>
                    </ref>
                                    <ref id="ref18">
                        <label>18</label>
                        <mixed-citation publication-type="journal">18. Benatar A, Vaughan J, Nicolini U, et al. Prenatal
pericardiocenthesis: Its role in the management of
intrapericardial teratoma. Obstet Gynecol 1992;79:856-9.</mixed-citation>
                    </ref>
                                    <ref id="ref19">
                        <label>19</label>
                        <mixed-citation publication-type="journal">19. Thorp JA, Geidt A, Gelatt M, et al. Decompression of
fetal cardiac tamponade caused by congenital capillary
hemangioma of the pericardium. Obstet Gynecol
2000;96:816-7. doi:10.1016/S0029-7844(00)01045-0.</mixed-citation>
                    </ref>
                                    <ref id="ref20">
                        <label>20</label>
                        <mixed-citation publication-type="journal">20. Laquay N, Ghazouani S, Vaccaroni L, et al. Intrapericardial
teratoma in newborn babies. Eur J Cardiothorac Surg
2003;23:642-4. doi: 10.1016/S1010-7940(02)00861-8.</mixed-citation>
                    </ref>
                                    <ref id="ref21">
                        <label>21</label>
                        <mixed-citation publication-type="journal">21. Kamil D, Geipel A, Schmitz C, et al. Fetal pericardial
teratoma causing cardiac insufficiency: prenatal diagnosis
and therapy. Ultrasound Obstet Gynecol 2006;28:972-8. doi:
10.1002/uog.3829.</mixed-citation>
                    </ref>
                                    <ref id="ref22">
                        <label>22</label>
                        <mixed-citation publication-type="journal">22. Czernik C, Stiller B, Hübler M, et al. Hydrops fetalis caused
by a large intrapericardial teratoma. Ultrasound Obstet
Gynecol 2006;28:972-8. doi:10.1012/uog.3852.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
