Systemic lupus erythematosus (SLE) is a challenge for pediatricians due to the heterogeneity of its clinical manifestations and the rarity of the disorder in this age group. Neuropsychiatric SLE (NPSLE) was defined especially in adult patients and the clinical course of this manifestation is still not clearly defined in the pediatric age group. We, here report a five-year old girl presenting with extensive maculopapular skin lesions, oral ulcers and neuropsychiatric symptoms. She had elevated titers of anti-nuclear antibody (ANA), Anti-ds-DNA, anti-histone antibodies and complement levels. Serum coxsackie and cytomegalovirus (CMV) IgM tests were positive, as well. Magnetic resonance imaging (MRI) of the brain demonstrated extended cerebral and cerebellar atrophy. Pediatricians should be attentive to the possibility of neurolupus for patients with neurological problems despite a young age at presentation. Appropriate therapy is a challenging task.
Keywords: Neuropsychiatric lupus, Pediatrics, CMV, Coxsackie
| Primary Language | en |
|---|---|
| Journal Section | Case Reports |
| Authors | |
| Dates |
Publication Date : September 14, 2015 |
| Bibtex | @ { marumj3180,
journal = {Marmara Medical Journal},
issn = {1019-1941},
eissn = {1309-9469},
address = {},
publisher = {Marmara University},
year = {2015},
volume = {28},
pages = {105 - 108},
doi = {10.5472/MMJcr.2802.08},
title = {Early-onset neurolupus: A challenge for pediatricians},
key = {cite},
author = {Barış, Safa and Karakoç-aydıner, Elif and Özen, Ahmet and Kaçmaz, Melissa and Namar, Medya and Yıldız, Nurdan and Türkdoğan, Dilşat and Barlan, İşıl}
} |
| APA | Barış, S , Karakoç-aydıner, E , Özen, A , Kaçmaz, M , Namar, M , Yıldız, N , Türkdoğan, D , Barlan, İ . (2015). Early-onset neurolupus: A challenge for pediatricians . Marmara Medical Journal , 28 (2) , 105-108 . DOI: 10.5472/MMJcr.2802.08 |
| MLA | Barış, S , Karakoç-aydıner, E , Özen, A , Kaçmaz, M , Namar, M , Yıldız, N , Türkdoğan, D , Barlan, İ . "Early-onset neurolupus: A challenge for pediatricians" . Marmara Medical Journal 28 (2015 ): 105-108 <https://dergipark.org.tr/en/pub/marumj/issue/430/3180> |
| Chicago | Barış, S , Karakoç-aydıner, E , Özen, A , Kaçmaz, M , Namar, M , Yıldız, N , Türkdoğan, D , Barlan, İ . "Early-onset neurolupus: A challenge for pediatricians". Marmara Medical Journal 28 (2015 ): 105-108 |
| RIS | TY - JOUR T1 - Early-onset neurolupus: A challenge for pediatricians AU - Safa Barış , Elif Karakoç-aydıner , Ahmet Özen , Melissa Kaçmaz , Medya Namar , Nurdan Yıldız , Dilşat Türkdoğan , İşıl Barlan Y1 - 2015 PY - 2015 N1 - doi: 10.5472/MMJcr.2802.08 DO - 10.5472/MMJcr.2802.08 T2 - Marmara Medical Journal JF - Journal JO - JOR SP - 105 EP - 108 VL - 28 IS - 2 SN - 1019-1941-1309-9469 M3 - doi: 10.5472/MMJcr.2802.08 UR - https://doi.org/10.5472/MMJcr.2802.08 Y2 - 2021 ER - |
| EndNote | %0 Marmara Medical Journal Early-onset neurolupus: A challenge for pediatricians %A Safa Barış , Elif Karakoç-aydıner , Ahmet Özen , Melissa Kaçmaz , Medya Namar , Nurdan Yıldız , Dilşat Türkdoğan , İşıl Barlan %T Early-onset neurolupus: A challenge for pediatricians %D 2015 %J Marmara Medical Journal %P 1019-1941-1309-9469 %V 28 %N 2 %R doi: 10.5472/MMJcr.2802.08 %U 10.5472/MMJcr.2802.08 |
| ISNAD | Barış, Safa , Karakoç-aydıner, Elif , Özen, Ahmet , Kaçmaz, Melissa , Namar, Medya , Yıldız, Nurdan , Türkdoğan, Dilşat , Barlan, İşıl . "Early-onset neurolupus: A challenge for pediatricians". Marmara Medical Journal 28 / 2 (September 2015): 105-108 . https://doi.org/10.5472/MMJcr.2802.08 |
| AMA | Barış S , Karakoç-aydıner E , Özen A , Kaçmaz M , Namar M , Yıldız N , Türkdoğan D , Barlan İ . Early-onset neurolupus: A challenge for pediatricians. Marmara Med J. 2015; 28(2): 105-108. |
| Vancouver | Barış S , Karakoç-aydıner E , Özen A , Kaçmaz M , Namar M , Yıldız N , Türkdoğan D , Barlan İ . Early-onset neurolupus: A challenge for pediatricians. Marmara Medical Journal. 2015; 28(2): 105-108. |
| IEEE | S. Barış , E. Karakoç-aydıner , A. Özen , M. Kaçmaz , M. Namar , N. Yıldız , D. Türkdoğan and İ. Barlan , "Early-onset neurolupus: A challenge for pediatricians", Marmara Medical Journal, vol. 28, no. 2, pp. 105-108, Sep. 2015, doi:10.5472/MMJcr.2802.08 |
