mid blac sea j health sci

Middle Black Sea Journal of Health Science

2149-7796

Ordu University

10.19127/mbsjohs.1100337

Health Care Administration

Sağlık Kurumları Yönetimi

Menstrual Cycle Characteristics, Premenstrual Syndrome, and Anxiety in Midwifery Student Infected and Not Infected with COVID-19: A Comparative Study

https://orcid.org/0000-0003-1906-9537

Özşahin

Zeliha

İnönü Üniversitesi

https://orcid.org/0000-0002-5282-973X

Karakayalı Ay

Çiğdem

İnönü Üniversitesi

https://orcid.org/0000-0002-6443-8277

Karataş Okyay

Esra

Kahramanmaraş Sütçü İmam Üniversitesi

08 31 2022

8 3 411 421 04 08 2022 07 24 2022

2015

Middle Black Sea Journal of Health Science

Objective: Periods of crisis, fear, and stress target hypothalamic-gonadal axis of women in reproductive age and can have an impact on menstrual symptoms. This study was conducted to evaluate menstrual cycle, premenstrual syndrome and anxiety in midwifery students with or without COVID-19 disease.Methods: In this descriptive and comparative study, 216 young girls infected with COVID-19 in the last 6 months were compared with 634 midwifery students, who were not infected yet. “Personal Description Form”, “Premenstrual Syndrome Scale (PMSS)” and “State-Trait Anxiety Inventory (STAI)” were used to collect data. Results: In the study, it was determined that the mean scores of PMSS and STAI of midwifery students, who had COVID-19 disease were higher than those who did not. It was determined that the difference between the mean scores of PMSS and STAI of midwifery students had COVID-19 was statistically significant, while the difference between the mean scores of PMSS and STAI of midwifery students who did not have COVID-19 disease was not statistically significant. The difference between the prolongation of the two cycle intervals and the reduction of menstrual bleeding in midwifery students with and without COVID-19 disease was found to be statistically significant.Conclusion: The difference between the prolongation of the two cycle intervals and the reduction of menstrual bleeding in midwifery students with and without COVID-19 disease was found to be statistically significant. In addition, the study revealed that being diagnosed with COVID-19 increased the premenstrual symptoms and anxiety levels of single young girls.

COVID-19 Premenstrual syndrome Anxiety Menstrual period Menstrual irregularities

1. Sansone A, Mollaioli D, Ciocca G, Limoncin E, Colonnello E, Vena W et al. Addressing male sexual and reproductive health in the wake of COVID-19 outbreak. J Endocrinol Invest. 2021;44(2):223-231. doi:10.1007/s40618-020-01350-1

2. Stewart S, Newson L, Briggs TA, Grammatopoulos D, Young L, Gill P. Long COVID risk -a signal to address sex hormones and women's health. Lancet Reg Health Eur. 2021;11:100242. doi:10.1016/j.lanepe.2021.10024

3. Demirci M, Unlü O, Yigin A, Yildiz Zeyrek F. Pathogenesis of SARS-CoV-2 and Immune Response in COVID-19. Turk Mikrobiyol Cemiy Derg 2020;50(4):183-91 doi:10.5222/TMCD.2020.183

4. Li K, Chen G, Hou H, Liao Q, Chen J, Bai H et al.Analysis of sex hormones and menstruation in COVID-19 women of child-bearing age. Reprod Biomed Online. 2021;42(1):260-67. doi: 10.1016/j.rbmo.2020.09.020

5. Buran G, Gercek Oter E. Impact of the awareness and fear of COVID-19 on menstrual symptoms in women: a cross-sectional study. Health Care Women Int. 2022;43(4):413-27. doi: 10.1080/07399332.2021.2004149

6. Khan SM, Shilen A, Heslin KM, Ishimwe P, Allen AM, Jacobs ET et al. SARS-CoV-2 infection and subsequent changes in the menstrual cycle among participants in the Arizona CoVHORT study. Am J Obstet Gynecol. 2022;226(2):270-73.doi: 10.1016/j.ajog.2021.09.016

7. Yonkers KA, O'Brien PM, Eriksson E. Premenstrual syndrome. Lancet. 2008;371(9619):1200-10. doi:10.1016/S0140-6736(08)60527-9

8. Direkvand-Moghadam A, Sayehmiri K , Delpisheh A. Epidemiology of Premenstrual Syndrome (PMS)-A Systematic Review and Meta-Analysis Study. J Clin Diagn Res. 2014;8(2):106-9. doi: 10.7860/JCDR/2014/8024.4021

9. Sharp GC, Fraser A, Sawyer G, Kountourides G, Easey KE, Ford G et al. The COVID-19 pandemic and the menstrual cycle: research gaps and opportunities. Int J Epidemiol. 2021;dyab239. doi: 10.1093/ije/dyab239.

10. Ding T, Wang T, Zhang J, Cui P, Chen Z, Zhou S et al. Analysis of Ovarian Injury Associated With COVID-19 Disease in Reproductive-Aged Women in Wuhan, China: An Observational Study. Front Med (Lausanne). 2021;8:635255. doi: 10.3389/fmed.2021.635255

11. Phelan N, Behan LA, Owens L. The Impact of the COVID-19 Pandemic on Women's Reproductive Health. Front Endocrinol (Lausanne).2021;12:642755. doi:10.3389/fendo.2021.642755

12. Demir O, Sal H, Comba C. Triangle of COVID, anxiety and menstrual cycle. J Obstet Gynaecol. 2021;41(8):1257-61. doi:10.1080/01443615.2021.1907562

13. Horesh D, Brown AD. Traumatic stress in the age of COVID-19: A call to close critical gaps and adapt to new realities. Psychol Trauma. 2020;12(4):331-5. doi:10.1037/tra0000592

14. Yamamoto K, Okazaki A, Sakamoto Y, Funatsu M. The relationship between premenstrual symptoms, menstrual pain, irregular menstrual cycles, and psychosocial stress among Japanese college students. J Physiol Anthropol. 2009;28(3):129-36. doi:10.2114/jpa2.28.129

15. Sogut S, Dolu I, Cangol E. The relationship between COVID-19 knowledge levels and anxiety states of midwifery students during the outbreak: A cross-sectional web-based survey. Perspect Psychiatr Care. 2021;57(1):246-52. doi:10.1111/ppc.12555

16. Simsek Kücükkelepce D, Timur Tashan S. The effects of health belief model-based education and acupressure for coping with premenstrual syndrome on premenstrual symptoms and quality of life: A randomized-controlled trial. Perspect Psychiatr Care. 2021;57(1):189-97. doi:10.1111/ppc.12546

17. Gencdogan B. A new scale for premenstrual syndrome. Journal of Psychiatry in Turkey. 2006; 8(2): 81-87.

18. Oner N, Le Compte A. Handbook of the discontinuous state/trait anxiety inventory. First Edition. İstanbul: Boğaziçi University Publications;1983. p. 1-26.

19. Alpar R. Applied statistics and validity-reliability. Sixth Edition.Ankara: Detay Publishing; 2020.

20. Kurmanova AM, Kurmanova GM, Lokshin VN. Reproductive dysfunctions in viral hepatitis. Gynecol Endocrinol. 2016;32(sup2):37-40. doi:10.1080/09513590.2016.1232780

21. Schoenbaum EE, Hartel D, Lo Y, Howard AA, Floris-Moore M, Arnsten JH et al. HIV infection, drug use, and onset of natural menopause. Clin Infect Dis. 2005 Nov 15;41(10):1517-24. doi: 10.1086/497270

22. Chen T, Wu D, Chen H, Yan W, Yang D, Chen G et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ. 2020; 368:m1091. doi: 10.1136/bmj.m1091

23. Dağlı DA, Büyükbayram A, Arabacı LB. A Psychosocial approach on patients diagnosed with COVID-19 and their families. İKÇÜSBFD. 2020; 5(2):191-95.

24. Alvergne A, Vlajic Wheeler M, Högqvist Tabor V. Do sexually transmitted infections exacerbate negative premenstrual symptoms? Insights from digital health. Evol Med Public Health. 2018;2018(1):138-50. doi:10.1093/emph/eoy018

25. Davis HE, Assaf GS, McCorkell L, Wei H, Low RJ, Re'em Y et al. Characterizing long COVID in an international cohort: 7 months of symptoms and their impact. E Clinical Medicine. 2021;38:101019. doi:10.1016/j.eclinm.2021.101019

26. Doyle C, Swain WA, Ewald HA, Cook CL, Ewald PW. Sexually Transmitted Pathogens, Depression, and Other Manifestations Associated with Premenstrual Syndrome. Hum Nat. 2015;26(3):277-91. doi:10.1007/s12110-015-9238-3

27. Kazan OK, Guz G, Ozyıldız Guz H, Dilbaz N. State-trait anxiety levels in Turkey during COVID-19 pandemic and its relationship to somatosensory amplification. J Exp Clin Med. 2021; 38(1): 33-8. doi: 10.5835/jecm.omu.38.01.007

28. Shanbehzadeh S, Tavahomi M, Zanjari N, Ebrahimi-Takamjani I, Amiri-Arimi S. Physical and mental health complications post-COVID-19: Scoping review. J Psychosom Res. 2021;147:110525. doi:10.1016/j.jpsychores.2021.110525