Role of Hybrid Treatment Technique in Radiotherapy Planning for Early Stage Left Breast Cancer

Year 2023, Volume: 24 Issue: 2, 155 - 160, 30.06.2023

Dr. Nural Öztürk , Nurdan Özbek

Abstract

Objective: The application of effective techniques has an important place in the control of the disease in the breast, which is an anatomically complex region. The aim of this study is an early stage left breast irradiation, in addition to Intensity-Modulated Radiotherapy (IMRT), volumetric-modulated arc therapy (VMAT) plans, it is to compare the data obtained by the HYBRID planning technique obtained with 5 different loadings and also to determine the appropriate weight ratios in HYBRID plans in terms of critical organ doses.
Materials and Methods: IMRT and VMAT plans were prepared for all patients included in the study. HYBRID plans with different beam weight rates were prepared to determine the optimal dose distribution hybrid beam weight ratio. Dose distributions, heterogeneity, and conformity indices of all plans were compared among themselves. In addition, dosimetric comparison was made in terms of critical organ doses.
Results: In the study, it was seen that the HYBRID3 plan was statistically significant in terms of the heart dose. This result shows that in terms of cardiac dose, the HIBRID 3 plan provides the desired low dose in terms of cardiac diseases. Considering the Dmean (≤1 Gy) value of the contralateral breast (CB) for the plans created in this study, it was found that all HYBRID loading plans were statistically significant compared to the IMRT plans. HYBRID plans have the lowest CB Dmax.
Conclusion: If one is unable to obtain appropriate results with VMAT techniques, then HYBRID plans formed by the combination of IMRT and VMAT plans reduce organs at risk doses, in the mean time ensuring that the dose wraps around the planned target volume in a targeted manner.

Keywords

Breast cancer , Intensity-Modulated Radiotherapy , volumetric arc therapy , HYBRID plans , critical organ doses

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