Böbrek Taşı Tedavisinde Retrograd Intrarenal Cerrahinin Böbrek Fonksiyonuna Etkisi

Year 2021, Volume: 5 Issue: 1, 55 - 60, 23.04.2021

Volkan Selmi , Sercan Sarı , Ünal Öztekin , Mehmet Caniklioğlu , Levent Işıkay

https://doi.org/10.30565/medalanya.792118

Abstract

Amaç: Bu çalışmada, Retrograd İntrarenal Cerrahi sonrasında eGFR’yi analiz eder-ek böbrek fonksiyonundaki değişikliği değerlendirmeyi ve değişikliği etkileyen fak-törleri sunmayı amaçladık.

Yöntem: Mayıs 2018 ile Şubat 2019 arasında böbrek taşı nedeniyle RIRS yapılan 88 hastayı prospektif olarak analiz ettik. eGFR, ameliyat öncesi, ameliyat sonrası ilk gün, ameliyat sonrası ilk ay ve ameliyat sonrası üçüncü ayda MDRD formülü ile he-saplandı. Tüm veriler takip formuna kaydedildi. Tüm işlemler genel anestezi altında yapıldı.

Bulgular: Çalışmanın taşsızlık oranı %79,5 idi. Preoperatif eGFR 99,86 mL/da-k/1.73m2 idi. eGFR, postoperatif ilk günde 101.80 mL/dak/1,73m2 ve üçüncü ay takibinde 111,66 mL/dak/1,73m2 olarak hesaplandı. eGFR'deki değişiklik erken dönemde 1,94 mL/dak/1,73m2 ve uzun dönem takip döneminde 11,8 mL/dak/1,73m2 idi. Üçüncü ay takiplerinde preoperatif böbrek fonksiyonuna göre ve erken döneme göre eGFR'de istatistiksel olarak anlamlı bir iyileşme vardı.

Sonuç: Eski taş çıkarma yöntemlerinin aksine RIRS, postoperatif böbrek fonksiy-onunda stabilizasyon sağlayabilmektedir. Hatta preoperatif böbrek fonksiyonu bozuk olan hastalarda operasyon sonrası böbrek fonksiyonlarında düzelmeye yardımcı ola-bilmektedir. Ürologlar, ameliyat sonrası böbrek fonksiyonlarında iyileşme olmasını istedikleri hastalarda RIRS seçeneğini akılda tutabilirler.

Keywords

Üreteroskopi,, litotripsi,, böbrek,, fonksiyon,

Supporting Institution

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Project Number

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Thanks

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The Effect of Retrograde Intrarenal Surgery on Kidney Function in Renal Stone Treatment

Abstract

Aim: In this study, we aimed to evaluate the alteration in renal function by analyzing the estimated glomerular filtration rate after Retrograde Intrarenal Surgery, and pres-ent the factors which have an impact on alteration.

Methods: We analyzed 88 patients who underwent RIRS for renal stones between May 2018 and February 2019, prospectively. Estimated glomerular filtration rate was calculated by modification of diet in renal disease (MDRD) formula preoperatively, on the first postoperative day, on the first postoperative month and the third post-operative month. All data was recorded on the follow-up form. All procedures were performed under general anesthesia.

Results: The stone-free rate of the study was 79.5%. Preoperative eGFR was 99.86 mL/min/1.73m2 for the study group. The eGFR was calculated 101.80 mL/min/1.73m2 on the first postoperative day and 111.66 mL/min/1.73m2 on the third-month fol-low-up. The change in eGFR was 1.94 mL/min/1.73m2 in the early period and 11.8 mL/min/1.73m2 in the long-term follow-up period. There was a statistically significant improvement in eGFR in the long-term follow-up period than the early period when compared to preoperative renal function.

Conclusion: On the contrary of former stone removal modalities, RIRS can stabilize postoperative kidney function. It may even help improve postoperative kidney func-tion in patients with preoperative renal dysfunction. Urologists may keep in mind the RIRS option in patients with this condition.

Keywords

Ureteroscopy,, lithotripsy,, kidney,, function,

Project Number

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