Does Fetal Renal Disease Have a Hemodynamic Effect in the Prenatal Period? A Detailed Analysis Method with Fetal Echocardiography

Year 2024, Volume: 6 Issue: 3, 376 - 381

Seval Yılmaz Ergani , Osman Yılmaz

https://doi.org/10.37990/medr.1511470

Abstract

Aim: Is there a change in the circulatory system in fetuses with renal disease in the prenatal period to make hemodynamic assessments. In addition, fetal cardiac functions in the same patients will be studied in detail using fetal echocardiography.
Material and Method: Thirty-one fetuses with renal disease were included in the study; 4 with polycystic kidneys, 4 with bilateral hydronephrosis, 12 with unilateral hydronephrosis, and 28 with pelvicalyceal ectasia. In the control group, there were 30 fetuses of the same gestational week without renal disease. The circulatory system and hemodynamic status were examined in detail by fetal echocardiography in both groups.
Results: High umbilical artery pulsatility index (PI) values were observed in 2 fetuses with bilateral hydronephrosis and 2 fetuses with unilateral hydronephrosis. The PI values of the middle cerebral artery were high in 2 fetuses with bilateral hydronephrosis and 2 cases with isolated pelvicalyceal ectasia. When the right and left myocardial performance index values of fetuses with renal disease were compared with normal fetuses, no significant results were observed, but the tricuspid valve pulse Doppler was abnormal in fetuses with fetal kidney disease. In addition, the right spherical index was higher in fetuses with renal disease than in the control group.
Conclusion: Although there is no functional change, morphologic findings of right ventricular overload can be observed in fetuses with fetal renal disease.

Keywords

Fetal renal disease, hydronephrosis, polycystic kidney disease, fetal echocardiography, myocardial performance index

Ethical Statement

The study protocol was approved by Ankara Etlik Zubeyde Hanim Women’s Health Training and Research Hospital Institutional Review Board with the decision number of 05/01/2022/3. The authors have confirmed that they have complied with the World Medical Association Declaration of Helsinki regarding the ethical conduct of research involving human subjects.

Supporting Institution

Yok

Thanks

Yok

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