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            <front>

                <journal-meta>
                                                                <journal-id>mersin univ saglık bilim derg</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Mersin Üniversitesi Sağlık Bilimleri Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">1308-0830</issn>
                                                                                            <publisher>
                    <publisher-name>Mersin University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.26559/mersinsbd.1109724</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Health Care Administration</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Sağlık Kurumları Yönetimi</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <trans-title-group xml:lang="en">
                                    <trans-title>Clinical, biochemical and radiological retrospective analysis in patients with adrenal incidentaloma</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>Adrenal insidentaloma’lı hastalarda klinik, biyokimyasal ve radyolojik retrospektif analiz</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-7559-8973</contrib-id>
                                                                <name>
                                    <surname>Eser</surname>
                                    <given-names>Zeynep Ebru</given-names>
                                </name>
                                                                    <aff>MERSİN ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-6558-6354</contrib-id>
                                                                <name>
                                    <surname>Gen</surname>
                                    <given-names>Ramazan</given-names>
                                </name>
                                                                    <aff>MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-8666-6177</contrib-id>
                                                                <name>
                                    <surname>Eser</surname>
                                    <given-names>Kadir</given-names>
                                </name>
                                                                    <aff>MERSİN ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-4160-7610</contrib-id>
                                                                <name>
                                    <surname>Sezer</surname>
                                    <given-names>Kerem</given-names>
                                </name>
                                                                    <aff>MERSİN ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-3819-5061</contrib-id>
                                                                <name>
                                    <surname>Akbay</surname>
                                    <given-names>Esen</given-names>
                                </name>
                                                                    <aff>MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20220831">
                    <day>08</day>
                    <month>31</month>
                    <year>2022</year>
                </pub-date>
                                        <volume>15</volume>
                                        <issue>2</issue>
                                        <fpage>382</fpage>
                                        <lpage>392</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20220429">
                        <day>04</day>
                        <month>29</month>
                        <year>2022</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20220810">
                        <day>08</day>
                        <month>10</month>
                        <year>2022</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2008, Mersin Üniversitesi Sağlık Bilimleri Dergisi</copyright-statement>
                    <copyright-year>2008</copyright-year>
                    <copyright-holder>Mersin Üniversitesi Sağlık Bilimleri Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="en">
                            <p>Introduction: The aim of this study was to evaluate the epidemiological, demographic, clinical features, treatment approaches and survival of patients followed up for adrenal incidentaloma. Methods: The data of 46 patients who underwent treatment and follow-up for adrenal incidentaloma in Mersin University Health Research and Practice Hospital, Endocrinology Department between 2010 and 2014 were retrospectively analyzed. Results: The study group consisted of 13 male and 33 female patients. The mean age was 54.09 ± 10.7 years. The most common reason for admission was abdominal pain in 34.78% of patients, the most commonly diagnosed radiological method was 60.87% dynamic surrenal CT, and the most common localization was right surrenal gland. The mean diameter of the mass was 26.8±16.5 mm. The prevalence of hypertension was 50%, obesity was 47.8%, type 2 diabetes was 21.7%, osteoporosis was 42.8% and metabolic syndrome was 41.3%. According to the results of hormonal evaluation, 82.61% of the patients had dysfunctional adrenal adenoma (FAA), 15.21% of them had subclinical Cushing syndrome (SCS) and 2.1% of them had aldesteronoma. Myelolipoma, benign pheochromocytoma and adrenocortical adenoma were diagnosed in 8 patients who underwent adrenalectomy. One patient died due to liver failure. No hormonal activation and lesion size growth was detected in the follow-up of the patients. Conclusion: Because of the different pathological and radiological features of AI, it is important to evaluate demographic, etiological, clinical, laboratory and radiological data as a whole in treatment and follow-up.</p></trans-abstract>
                                                                                                                                    <abstract><p>Giriş: Bu çalışmada, adrenal insidentaloma nedeniyle takip edilen hastaların epidemiyolojik, demografik, klinik özellikleri, tedavi yaklaşımları ve yaşam sürelerinin değerlendirilmesi amaçlanmıştır. Yöntem: 2010–2014 yılları arasında Mersin Üniversitesi Araştırma ve Uygulama Hastanesi Endokrinoloji Bölümünde adrenal insidentaloma nedeniyle tedavi ve takipleri yapılan 46 hastanın verileri retrospektif olarak incelendi. Bulgular: Çalışmaya alınan olguların 13’ü erkek, 33’ü kadın ve yaş ortalaması 54.09±10.7 idi. En sık başvuru nedeni %34.78 hastada karın ağrısı, en sık tanı konulan radyolojik yöntem % 60.87 dinamik sürrenal BT, en sık yerleşim yeri sol surrenal bezdi. Kitle çapı ortalama 26.8±16.5 mm arasında idi. Hipertansiyon sıklığı %50, obezite sıklığı %47.8, tip 2 diyabet sıklığı %21.7, osteoporoz sıklığı ise %42.8 ve metabolik sendrom sıklığı %41.3 olarak saptandı. Hormonal değerlendirme sonuçlarına göre %82.61’inde fonksiyonsuz adrenal adenom (FAA), %15.21’inde subklinik Cushing sendromu (SCS), %2.1’inde aldesteronoma görüldü. Adrenalektomiye giden 8 olguda myelolipom, feokromasitoma ve adrenokortikal adenom tanısı konuldu. Bir hasta karaciğer yetmezliğinden exitus oldu. Hastaların takiplerinde hormonal aktivasyon ve lezyon boyutunda büyüme saptanmadı. Sonuç: AI’ların çok farklı patolojik ve radyolojik görünümler ile karşımıza çıkmasından dolayı demografik, etiyolojik, klinik, laboratuar ve radyolojik verilerin bir bütün olarak değerlendirilmesi tedavi ve takibinde önemlidir.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Adrenal insidentaloma</kwd>
                                                    <kwd>  subklinik cushing sendromu</kwd>
                                                    <kwd>  fonksiyonsuz adrenal adenom</kwd>
                                                    <kwd>  teşhis</kwd>
                                                    <kwd>  tedavi</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="en">
                                                    <kwd>Adrenal incidentaloma</kwd>
                                                    <kwd>  subclinical Cushing syndrome</kwd>
                                                    <kwd>  dysfunctional adrenal adenoma</kwd>
                                                    <kwd>  diagnosis</kwd>
                                                    <kwd>  treatment</kwd>
                                            </kwd-group>
                                                                                                                                    <funding-group specific-use="FundRef">
                    <award-group>
                                                    <funding-source>
                                <named-content content-type="funder_name">yok</named-content>
                            </funding-source>
                                                                            <award-id>yok</award-id>
                                            </award-group>
                </funding-group>
                                </article-meta>
    </front>
    <back>
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