<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="reviewer-report"        dtd-version="1.4">
            <front>

                <journal-meta>
                                                                <journal-id>mersin univ saglık bilim derg</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Mersin Üniversitesi Sağlık Bilimleri Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">1308-0830</issn>
                                                                                            <publisher>
                    <publisher-name>Mersin University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.26559/mersinsbd.327765</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Health Care Administration</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Sağlık Kurumları Yönetimi</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Ortodontik diş hareketini hızlandıran farmakolojik uygulamalar ve mekanik-fiziksel stimülasyonlar</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-5295-2722</contrib-id>
                                                                <name>
                                    <surname>Türker</surname>
                                    <given-names>Gökhan</given-names>
                                </name>
                                                                    <aff>Mersin Üniversitesi, Diş Hekimliği Fakültesi, Ortodonti Anabilim Dalı, Mersin</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-2759-8562</contrib-id>
                                                                <name>
                                    <surname>Akgün</surname>
                                    <given-names>Gizem</given-names>
                                </name>
                                                                    <aff>Erciyes Üniversitesi, Diş Hekimliği Fakültesi, Ortodonti Anabilim Dalı, Mersin</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20180415">
                    <day>04</day>
                    <month>15</month>
                    <year>2018</year>
                </pub-date>
                                        <volume>11</volume>
                                        <issue>1</issue>
                                        <fpage>75</fpage>
                                        <lpage>85</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20170711">
                        <day>07</day>
                        <month>11</month>
                        <year>2017</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20171002">
                        <day>10</day>
                        <month>02</month>
                        <year>2017</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2008, Mersin Üniversitesi Sağlık Bilimleri Dergisi</copyright-statement>
                    <copyright-year>2008</copyright-year>
                    <copyright-holder>Mersin Üniversitesi Sağlık Bilimleri Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Dişlerekuvvet uygulanarak estetik ve fonksiyonel açıdan kabul edilebilir en iyiokluzyonu sağlamayı hedefleyen ortodontik tedaviler, genellikle uzun bir süreciiçeren, zaman alıcı uygulamalardır. Tedavi süresinin uzun olması, hastalarıntedaviye olan uyumlarının azalmasının yanında alveolar kemik rezorpsiyonu, kökrezorpsiyonu ve diş çürükleri gibi çeşitli istenmeyen etkilerin oluşmasınaneden olabilmektedir. Bu istenmeyen etkilerin engellenmesi veya en azaindirgenmesi için diş hareketini hızlandırarak tedavi süresini kısaltmakamacıyla çeşitli yöntemler geliştirilmiştir. Bu yöntemler, cerrahi destekliuygulamalar, farmakolojik uygulamalar ve mekanik-fiziksel stimülasyonlar olmaküzere genel olarak üç ana başlıkta incelenmektedir. Bu derlemede, ortodontikdiş hareketini hızlandırmak amacıyla uygulanan farmakolojik uygulamalar vemekanik-fiziksel stimülasyonlar hakkında bilgiler sunulmuştur.</p></abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Diş hareketi</kwd>
                                                    <kwd>  mekanik</kwd>
                                                    <kwd>  farmakolojik</kwd>
                                            </kwd-group>
                            
                                                                                                                        </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">Ren A, Lv T, Kang N, Zhao B, Chen Y, Bai D. Rapid orthodontic tooth movement aided by alveolar surgery in beagles. Am J Orthod Dentofacial Orthop. 2007;131(2):160. e1-. e10.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">Buschang PH, Campbell PM, Ruso S. Accelerating tooth movement with corticotomies: is it possible and desirable? Semin Orthod. 2012;18(4):286-294.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">Kurol J, Owman-Moll P, Lundgren D. Time-related root resorption after application of acontrolled continuous orthodontic force. Am J Orthod Dentofacial Orthop. 1996;110(3):303-310.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">Ristic M, Svabic MV, Sasic M, Zelic O. Clinical and microbiological effects of fixed orthodontic appliances on periodontal tissues in adolescents. Orthod Craniofac Res. 2007;10(4):187-195.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">Ge MK, He WL, Chen J, Wen C, Yin X, Hu ZA, Liu ZP, Zou SJ. Efficacy of low-level laser therapy for accelerating tooth movement during orthodontic treatment: a systematic review and meta-analysis. Lasers Med Sci. 2015;30(5):1609-1618.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">Engström C, Granström G, Thilander B. Effect of orthodontic force on periodontal tissue metabolism a histologic and biochemical study in normal and hypocalcemic young rats. Am J Orthod Dentofacial Orthop. 1988;93(6):486-495.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">Nimeri G, Kau CH, Abou-Kheir NS, Corona R. Acceleration of tooth movement during orthodontic treatment-a frontier in orthodontics. Prog Orthod. 2013;14(1):42.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">Ileri Z, Akin M, Erdur EA, Dagi HT, Findik D. Bacteremia after piezocision. Am J Orthod Dentofac Orthop. 2014;146(4):430-436.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">Seifi M, Eslami B, Saffar AS. The effect of prostaglandin E2 and calcium gluconate on orthodontic tooth movement and root resorption in rats. Eur J Orthod. 2003;25(2):199-204.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">Yamasaki K, Shibata Y, Imai S, Tani Y, Shibasaki Y, Fukuhara T. Clinical application of prostaglandin E 1 (PGE 1) upon orthodontic tooth movement. Am J Orthod. 1984;85(6):508-518.</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">Mohammed AH, Tatakis DN, Dziak R. Leukotrienes in orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 1989;95(3):231-237.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">Kanzaki H, Chiba M, Arai K, Takahashi I, Haruyama N, Nishimura M, Mitani H. Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement. Gene Therapy. 2006;13(8):678-685</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">Brooks PJ, Heckler AF, Wei K, Gong SG. M-CSF accelerates orthodontic tooth movement by targeting preosteoclasts in mice. Angle Orthod. 2011;81(2):277-283.</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">Leiker BJ, Nanda RS, Currier GF, Howes RI, Sinha PK. The effects of exogenous prostaglandins on orthodontic tooth movement in rats. Am J Orthod Dentofacial Orthop. 1995;108(4):380-388.</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">Hashimoto F, Kobayashi Y, Mataki S, Kobayashi K, Kato Y, Sakai H. Administration of osteocalcin accelerates orthodontic tooth movement induced by a closed coil spring in rats. Eur J Orthod. 2001;23(5):535-545.</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">Akın E, Gurton AU, Ölmez H. Effects of nitric oxide in orthodontic tooth movement in rats. Am J Orthod Dentofacial Orthop. 2004;126(5):608-614.</mixed-citation>
                    </ref>
                                    <ref id="ref17">
                        <label>17</label>
                        <mixed-citation publication-type="journal">Kaku M, Kohno S, Kawata T, Fujita T, Tokimasa C, Tsutsui K, et al. Effects of vascular endothelial growth factor on osteoclast induction during tooth movement in mice. J Dent Res. 2001;80(10):1880-1883.</mixed-citation>
                    </ref>
                                    <ref id="ref18">
                        <label>18</label>
                        <mixed-citation publication-type="journal">Ong CK, Walsh LJ, Harbrow D, Taverne AA, Symons AL. Orthodontic tooth movement in the prednisolone-treated rat. Angle Orthod. 2000;70(2):118-125.</mixed-citation>
                    </ref>
                                    <ref id="ref19">
                        <label>19</label>
                        <mixed-citation publication-type="journal">Ashcraft MB, Southard KA, Tolley EA. The effect of corticosteroid-induced osteoporosis on orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 1992;102(4):310-319.</mixed-citation>
                    </ref>
                                    <ref id="ref20">
                        <label>20</label>
                        <mixed-citation publication-type="journal">Goldie RS, King GJ. Root resorption and tooth movement in orthodontically treated, calcium-deficient, and lactating rats. Am J Orthod. 1984;85(5):424-430.</mixed-citation>
                    </ref>
                                    <ref id="ref21">
                        <label>21</label>
                        <mixed-citation publication-type="journal">Gianelly AA, Schnur RM. The use of parathyroid hormone to assist orthodontic tooth movement. Am J Orthod. 1969;55(3):305.</mixed-citation>
                    </ref>
                                    <ref id="ref22">
                        <label>22</label>
                        <mixed-citation publication-type="journal">Takano-Yamamoto T, Kawakami M, Yamashiro T. Effect of age on the rate of tooth movement in combination with local use of 1, 25 (OH) 2D3 and mechanical force in the rat. J Dent Res. 1992;71(8):1487-1492.</mixed-citation>
                    </ref>
                                    <ref id="ref23">
                        <label>23</label>
                        <mixed-citation publication-type="journal">Kale S, Kocadereli Il, Atilla P, Aşan E. Comparison of the effects of 1, 25 dihydroxycholecalciferol and prostaglandin E 2 on orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 2004;125(5):607-614.</mixed-citation>
                    </ref>
                                    <ref id="ref24">
                        <label>24</label>
                        <mixed-citation publication-type="journal">Collins MK, Sinclair PM. The local use of vitamin D to increase the rate of orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 1988;94(4):278-284.</mixed-citation>
                    </ref>
                                    <ref id="ref25">
                        <label>25</label>
                        <mixed-citation publication-type="journal">Liu ZJ, King GJ, Gu GM, Shin JY, Stewart DR. Does human relaxin accelerate orthodontic tooth movement in rats? Ann N Y Acad Sci. 2005;1041(1):388-394.</mixed-citation>
                    </ref>
                                    <ref id="ref26">
                        <label>26</label>
                        <mixed-citation publication-type="journal">Krishnan V, Davidovitch Ze. Cellular, molecular, and tissue-level reactions to orthodontic force. Am J Orthod Dentofacial Orthop. 2006;129(4):469. e1-. e32.</mixed-citation>
                    </ref>
                                    <ref id="ref27">
                        <label>27</label>
                        <mixed-citation publication-type="journal">Sakuma Y, Li Z, Pilbeam CC, Alander CB, Chikazu D, Kawaguchi H, Raisz LG. Stimulation of cAMP production and cyclooxygenase-2 by prostaglandin E 2 and selective prostaglandin receptor agonists in murine osteoblastic cells. Bone. 2004;34(5):827-834.</mixed-citation>
                    </ref>
                                    <ref id="ref28">
                        <label>28</label>
                        <mixed-citation publication-type="journal">Itonaga I, Sabokbar A, Neale SD, Athanasou NA. 1, 25-Dihydroxyvitamin D 3 and prostaglandin E 2 act directly on circulating human osteoclast precursors. Biochem Biophys Res Commun. 1999;264(2):590-595.</mixed-citation>
                    </ref>
                                    <ref id="ref29">
                        <label>29</label>
                        <mixed-citation publication-type="journal">Magnusson P, Hager A, Larsson L. Serum osteocalcin and bone and liver alkaline phosphatase isoforms in healthy children and adolescents. Pediatr Res. 1995;38(6):955-961.</mixed-citation>
                    </ref>
                                    <ref id="ref30">
                        <label>30</label>
                        <mixed-citation publication-type="journal">Brennan P, Thomas G, Langdon J. The role of nitric oxide in oral diseases. Arch Oral Biol. 2003;48(2):93-100.</mixed-citation>
                    </ref>
                                    <ref id="ref31">
                        <label>31</label>
                        <mixed-citation publication-type="journal">D&#039;Attillio M, Di Maio F, D&#039;Arcangela C, Rita Filippi M, Felaco M, Lohinai Z, Festa F, Perinetti G. Gingival endothelial and inducible nitric oxide synthase levels during orthodontic treatment: a cross-sectional study. Angle Orthod. 2004;74(6):851-858.</mixed-citation>
                    </ref>
                                    <ref id="ref32">
                        <label>32</label>
                        <mixed-citation publication-type="journal">Zhang F, Richards L, Angel MF, Zhang J, Liu H, Dorsett-Martin W. Accelerating flap maturation by vascular endothelium growth factor in a rat tube flap model. Br J Plast Surg. 2002;55(1):59-63.</mixed-citation>
                    </ref>
                                    <ref id="ref33">
                        <label>33</label>
                        <mixed-citation publication-type="journal">Kohno S, Kaku M, Kawata T, Fujita T, Tsutsui K, Ohtani J, Tenjo K, Tohma Y, Motokawa M, Shigekawa M, Kamada H, Tanne K. Neutralizing effects of an anti-vascular endothelial growth factor antibody on tooth movement. Angle Orthod. 2005;75(5):797-804.</mixed-citation>
                    </ref>
                                    <ref id="ref34">
                        <label>34</label>
                        <mixed-citation publication-type="journal">Lems W, Jacobs J, Van Rijn H, Bijlsma J. Changes in calcium and bone metabolism during treatment with low dose prednisone in young, healthy, male volunteers. Clin Rheumatol. 1995;14(4):420-424.</mixed-citation>
                    </ref>
                                    <ref id="ref35">
                        <label>35</label>
                        <mixed-citation publication-type="journal">Reeve J, Zanelli JM. Parathyroid hormone and bone. Clin Sci. 1986;71(3):231-238</mixed-citation>
                    </ref>
                                    <ref id="ref36">
                        <label>36</label>
                        <mixed-citation publication-type="journal">Madan MS, Liu ZJ, Gu GM, King GJ. Effects of human relaxin on orthodontic tooth movement and periodontal ligaments in rats. Am J Orthod Dentofacial Orthop. 2007;131(1):8. e1-8. e10.</mixed-citation>
                    </ref>
                                    <ref id="ref37">
                        <label>37</label>
                        <mixed-citation publication-type="journal">Rodan GA, Bourret LA, Norton LA. DNA synthesis in cartilage cells is stimulated by oscillating electric fields. Science. 1978;199(4329):690-692.</mixed-citation>
                    </ref>
                                    <ref id="ref38">
                        <label>38</label>
                        <mixed-citation publication-type="journal">Lavine L, Lustrin I, Rinaldi R, Shamos M. Clinical and ultrastructural investigations of electrical enhancement of bone healing. Ann N Y Acad Sci. 1974;238(1):552-563.</mixed-citation>
                    </ref>
                                    <ref id="ref39">
                        <label>39</label>
                        <mixed-citation publication-type="journal">Karanth H, Shetty K. Orthodontic tooth movement and bioelectricity. Indian J Dent Res. 2000;12(4):212-221.</mixed-citation>
                    </ref>
                                    <ref id="ref40">
                        <label>40</label>
                        <mixed-citation publication-type="journal">Stark TM, Sinclair PM. Effect of pulsed electromagnetic fields on orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 1987;91(2):91-104.</mixed-citation>
                    </ref>
                                    <ref id="ref41">
                        <label>41</label>
                        <mixed-citation publication-type="journal">Darendeliler MA, Zea A, Shen G, Zoeliner H. Effects of pulsed electromagnetic field vibration on tooth movement induced by magnetic and mechanical forces: a preliminary study. Aust Dent J. 2007;52(4):282-287.</mixed-citation>
                    </ref>
                                    <ref id="ref42">
                        <label>42</label>
                        <mixed-citation publication-type="journal">Showkatbakhsh R, Jamilian A, Showkatbakhsh M. The effect of pulsed electromagnetic fields on the acceleration of tooth movement. World J Orthod. 2010;11(4):e52-e56</mixed-citation>
                    </ref>
                                    <ref id="ref43">
                        <label>43</label>
                        <mixed-citation publication-type="journal">Krishtab S, Doroshenko S, Liutik G. Use of vibratory action on the teeth to accelerate orthodontic treatment. Stomatologii͡a. 1986;65(3):61.</mixed-citation>
                    </ref>
                                    <ref id="ref44">
                        <label>44</label>
                        <mixed-citation publication-type="journal">Ohmae M, Saito S, Morohashi T, Qu H, Seki K, Kurabayashi H. Biomechanical acceleration of experimental tooth movement by ultrasonic vibration in vivo—part 1: Homo-directional application of ultrasonication to orthodontic force. Orthod Waves. 2001;60:201-212.</mixed-citation>
                    </ref>
                                    <ref id="ref45">
                        <label>45</label>
                        <mixed-citation publication-type="journal">Nishimura M, Chiba M, Ohashi T, Sato M, Shimizu Y, Igarashi K, Mitani H. Periodontal tissue activation by vibration: intermittent stimulation by resonance vibration accelerates experimental tooth movement in rats. Am J Orthod Dentofacial Orthop. 2008;133(4):572-583</mixed-citation>
                    </ref>
                                    <ref id="ref46">
                        <label>46</label>
                        <mixed-citation publication-type="journal">Miles P, Smith H, Weyant R, Rinchuse DJ. The effects of a vibrational appliance on tooth movement and patient discomfort: a prospective randomised clinical trial. Aust Orthod J. 2012;28(2):213.</mixed-citation>
                    </ref>
                                    <ref id="ref47">
                        <label>47</label>
                        <mixed-citation publication-type="journal">Leethanakul C, Suamphan S, Jitpukdeebodintra S, Thongudomporn U, Charoemratrote C. Vibratory stimulation increases interleukin-1 beta secretion during orthodontic tooth movement. Angle Orthod. 2015;86(1):74-80.</mixed-citation>
                    </ref>
                                    <ref id="ref48">
                        <label>48</label>
                        <mixed-citation publication-type="journal">Altan AB. Ortodontide lazer uygulamaları. Turkiye Klinikleri Journal of Orthodontics-Special Topics. 2015;1(1):42-49.</mixed-citation>
                    </ref>
                                    <ref id="ref49">
                        <label>49</label>
                        <mixed-citation publication-type="journal">Eells JT, Wong-Riley MT, VerHoeve J, Henry M, Buchman EV, Kane MP, Gould LJ, Das R, Jett M, Hodgson BD, Margolis D, Whelan HT. Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy. Mitochondrion. 2004;4(5):559-567</mixed-citation>
                    </ref>
                                    <ref id="ref50">
                        <label>50</label>
                        <mixed-citation publication-type="journal">Kawasaki K, Shimizu N. Effects of low-energy laser irradiation on bone remodeling during experimental tooth movement in rats. Lasers Surg Med. 2000;26(3):282-291.</mixed-citation>
                    </ref>
                                    <ref id="ref51">
                        <label>51</label>
                        <mixed-citation publication-type="journal">Cruz DR, Kohara EK, Ribeiro MS, Wetter NU. Effects of low intensity laser therapy on the orthodontic movement velocity of human teeth: A preliminary study. Lasers Surg Med. 2004;35(2):117-120.</mixed-citation>
                    </ref>
                                    <ref id="ref52">
                        <label>52</label>
                        <mixed-citation publication-type="journal">Youssef M, Ashkar S, Hamade E, Gutknecht N, Lampert F, Mir M. The effect of low-level laser therapy during orthodontic movement: a preliminary study. Lasers Med Sci. 2008;23(1):27-33.</mixed-citation>
                    </ref>
                                    <ref id="ref53">
                        <label>53</label>
                        <mixed-citation publication-type="journal">Doshi-Mehta G, Bhad-Patil WA. Efficacy of low-intensity laser therapy in reducing treatment time and orthodontic pain: a clinical investigation. Am J Orthod Dentofacial Orthop. 2012;141(3):289-297.</mixed-citation>
                    </ref>
                                    <ref id="ref54">
                        <label>54</label>
                        <mixed-citation publication-type="journal">da Silva Sousa MV, Scanavini MA, Sannomiya EK, Velasco LG, Angelieri F. Influence of low-level laser on the speed of orthodontic movement. Photomed Laser Surg. 2011;29(3):191-196.</mixed-citation>
                    </ref>
                                    <ref id="ref55">
                        <label>55</label>
                        <mixed-citation publication-type="journal">Limpanichkul W, Godfrey K, Srisuk N, Rattanayatikul C. Effects of low level laser therapy on the rate of orthodontic tooth movement. Orthod Craniofac Res. 2006;9(1):38-43.</mixed-citation>
                    </ref>
                                    <ref id="ref56">
                        <label>56</label>
                        <mixed-citation publication-type="journal">Goulart CS, Nouer PRA, Mouramartins L, Garbin IU, Lizarelli RdFZ. Photoradiation and orthodontic movement: experimental study with canines. Photomed Laser Surg. 2006;24(2):192-196.</mixed-citation>
                    </ref>
                                    <ref id="ref57">
                        <label>57</label>
                        <mixed-citation publication-type="journal">Wong-Riley MT, Liang HL, Eells JT, Chance B, Henry MM, Buchmann E, Kane M, Whelan HT. Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins. Role of Cytochrome c oxidase. J Biol Chem. 2005;280(6):4761-4771.</mixed-citation>
                    </ref>
                                    <ref id="ref58">
                        <label>58</label>
                        <mixed-citation publication-type="journal">Ekizer A, Uysal T, Güray E, Akkuş D. Effect of LED-mediated-photobiomodulation therapy on orthodontic tooth movement and root resorption in rats. Lasers Med Sci. 2015;30(2):779-785.</mixed-citation>
                    </ref>
                                    <ref id="ref59">
                        <label>59</label>
                        <mixed-citation publication-type="journal">Kau CH, Kantarci A, Shaughnessy T, Vachiramon A, Santiwong P, de la Fuente A, Skrenes D, Ma D, Brawn P. Photobiomodulation accelerates orthodontic alignment in the early phase of treatment. Prog Orthod. 2013;14:30.</mixed-citation>
                    </ref>
                                    <ref id="ref60">
                        <label>60</label>
                        <mixed-citation publication-type="journal">Ekizer A, Türker G, Uysal T, Güray E, Taşdemir Z. Light emitting diode mediated photobiomodulation therapy improves orthodontic tooth movement and miniscrew stability: A randomized controlled clinical trial. Lasers Surg Med. 2016;48(10):936-943</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
