mersin univ saglık bilim derg Mersin Üniversitesi Sağlık Bilimleri Dergisi 1308-0830 Mersin University 10.26559/mersinsbd.398926 Health Care Administration Sağlık Kurumları Yönetimi Pelargonium quercetorum Agnew. bitkisinin antioksidan aktivitesinin belirlenmesi https://orcid.org/0000-0001-5829-6914 Şeker Karatoprak Gökçe Erciyes Üniversitesi https://orcid.org/0000-0001-5814-614X Fırat Mehmet Yüzüncü yıl üniversitesi https://orcid.org/0000-0002-1559-998X Koşar Müberra Doğu Akdeniz Üniversitesi 08 15 2018 11 2 174 183 02 26 2018 05 03 2018 Copyright © 2008, Mersin Üniversitesi Sağlık Bilimleri Dergisi 2008 Mersin Üniversitesi Sağlık Bilimleri Dergisi

Amaç: Antiparaziter olarak geleneksel kullanımımevcut olan Geraniaceae familyasına dahil Pelargoniumquercetorum Agnew.’in toplam fenolik madde miktarı ve antioksidanaktivitesinin araştırılması amaçlanmıştır.Yöntem: P. quercetorum'un toprakaltı kısımlarından hazırlanan %70 metanol ve %11 etanol ekstreleri ile topraküstü kısmından hazırlanan %70 metanol ekstresinin toplam fenolik, flavonoit veflavonol içerikleri spektrofotometrik olarak incelenmiştir. Ekstrelerinantioksidan aktivitelerini belirlemek amacıyla 1.1-difenil-2-pikrilhidrazil(DPPHl) ve 2.2’-azino-bis (3-etilbenzotiazolin-6-sulfonik asit) (ABTS+l)radikal süpürücü etkileri, Fe(III)’ü Fe(II)’yeindirgeme özellikleri ve demir(II) şelat (kelat) aktiviteleriincelenmiştir. Bulgular ve Sonuç: %70Metanol kök ekstresinin toplam fenolik ve flavonoit (242.29 ± 5.52 mgGAE/gekstre,64.95 ± 2.93mgCA/gekstre) içerik bakımındanzengin olduğu ve antioksidan aktivite deneylerinde de güçlü etki gösterdiğibelirlenmiştir.

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