med j west black sea Medical Journal of Western Black Sea 2822-4302 2587-0602 Zonguldak Bulent Ecevit University 10.29058/mjwbs.1577524 Otorhinolaryngology Kulak Burun Boğaz The Effect of Halp Score on the Development of Pharyngocutaneous Fistula After Laryngectomy Larenjektomi Sonrası Faringokutanöz Fistül Gelişimi Üzerine Halp Skoru Etkisi https://orcid.org/0000-0001-8449-4965 Baklacı Deniz ZONGULDAK BÜLENT ECEVİT ÜNİVERSİTESİ https://orcid.org/0000-0002-7973-2719 Erdem Duygu ZONGULDAK BÜLENT ECEVİT ÜNİVERSİTESİ https://orcid.org/0009-0002-2135-0504 Saka Seda Nur ZONGULDAK BÜLENT ECEVİT ÜNİVERSİTESİ https://orcid.org/0000-0003-3975-3547 Kılıç Gökhan Furkan ZONGULDAK BÜLENT ECEVİT ÜNİVERSİTESİ https://orcid.org/0009-0004-2201-5649 Eralp Doğancan İstanbul Eğitim ve Araştırma Hastanesi 08 31 2025 9 2 158 165 11 01 2024 07 08 2025 Copyright © 2017, Medical Journal of Western Black Sea 2017 Medical Journal of Western Black Sea

Aim: Laryngeal cancers are prominent among head and neck cancers, and laryngectomy is commonly performed in advanced cases.Pharyngocutaneous fistula (PCF), a postoperative complication, negatively impacts quality of life, prolongs hospitalization, and delays treatment.The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score, calculated from hemoglobin, albumin, lymphocyte, and plateletlevels, reflects immune and nutritional status. Material and Methods: This retrospective study included 76 patients who underwent surgery for laryngeal cancer between January 2012and June 2024. Patients were grouped based on partial or total laryngectomy, and HALP scores were compared with the incidence of fistula.Results: In the total laryngectomy group, the mean HALP score was 33.42±17.17 for patients without fistula and 42.79±30.00 for those withfistula. No statistically significant difference was found between the two groups (p>0.05).Conclusion: No significant relationship was found between HALP score and PCF development. However, since hemoglobin and albuminmay be risk factors, larger, multicenter prospective studies are needed for a more comprehensive evaluation

Amaç: Larengeal kanserler, baş ve boyun kanserleri içinde önemli bir yer tutar ve ileri evre hastalarda genellikle larenjektomi uygulanır.Cerrahiden sonra gelişebilen farengokütanöz fistül (FKF), yaşam kalitesini düşürür, hastanede kalış süresini uzatır ve tedavi sürecini aksatır.Hemoglobin, Albumin, Lenfosit ve Platelet (HALP) skoru; hemoglobin, albümin, lenfosit ve trombosit parametrelerinin kullanıldığı, immün vebeslenme durumunu yansıtan bir biyomarkerdir.Gereç ve Yöntemler: Ocak 2012 - Haziran 2024 tarihleri arasında kliniğimizde larenks kanseri nedeniyle opere edilen 76 hasta retrospektifolarak değerlendirildi. Hastalar, kısmi veya total larenjektomi geçirmelerine göre gruplandırıldı ve HALP skorları ile fistül gelişimi karşılaştırıldı.Bulgular: Total larenjektomi yapılan ve fistül gelişmeyen hastaların ortalama HALP skoru 33.42±17.17, fistül gelişenlerin ise 42.79±30.00idi. Ancak gruplar arasında istatistiksel olarak anlamlı fark saptanmadı (p>0.05).Sonuç: HALP skoru ile FKF gelişimi arasında anlamlı bir ilişki bulunmadı. Ancak hemoglobin ve albümin düzeylerinin risk faktörü olabileceğigöz önünde bulundurularak, bu ilişkiyi değerlendirmek için daha geniş, çok merkezli ve prospektif çalışmalara ihtiyaç vardır.

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