Case Report
BibTex RIS Cite

Adult Tracheobronchomalacia that Progressed Following Radiotherapy in an Advanced-stage Lung Cancer Patient: A Rare Case Report

Year 2024, Volume: 8 Issue: 2, 201 - 206, 30.08.2024
https://doi.org/10.29058/mjwbs.1460900

Abstract

Tracheobronchomalacia (TBM) is the collapse of the trachea and bronchi, which leads to respiratory symptoms and complications, often on forced expiration. Radiotherapy (RT) is a rare cause of adult TBM.
Here, we report the first case of progressive TBM following palliative RT in a patient with squamous cell lung carcinoma. TBM was diagnosed by fiberoptic bronchoscopy and thoracic CT scans.
In patients with advanced-stage lung cancer who experience worsening dyspnea and cough following palliative RT, TBM should also be taken into account.

Ethical Statement

This retrospective review of patient data did not require ethical approval in accordance with local/national guidelines. The authors state that they have followed the principles outlined in the Declaration of Helsinki for all human or animal experimental investigations. Written informed consent was obtained from the patient for publication of this case report and any accompanying images.

Supporting Institution

Yoktur

Thanks

Yoktur

References

  • 1. Nuutinen J. Acquired tracheobronchomalacia. A clinical study with bronchological correlations. Ann Clin Res 1977;9(6):350- 355.
  • 2. Murgu SD, Colt HG. Treatment of adult tracheobronchomalacia and excessive dynamic airway collapse: an update. Treat Respir Med 2006;5(2):103-115.
  • 3. Buitrago DH, Wilson JL, Parikh A, Majid A, Gangadharan SP. Current concepts in severe adult tracheobronchomalacia: evaluation and treatment. J Thorac Dis 2017;9(1):E57-E66.
  • 4. Murgu S, Colt H. Tracheobronchomalacia and excessive dynamic airway collapse. Clin Chest Med 2013;34(3):527-555.
  • 5. Kamran A, Baird CW, Jennings RW. Tracheobronchomalacia, Tracheobronchial Compression, and Tracheobronchial Malformations: Diagnostic and Treatment Strategies. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2020;23:53-61.
  • 6. Wright CD. Tracheobronchomalacia and expiratory collapse of central airways. Thorac Surg Clin 2018;28(2):163-166.
  • 7. Kano Y, Sakurai H, Shidara J, Toida S, Yasuda H. Histopathological and immunohistochemical studies of acquired tracheobronchomalacia: an autopsy case report. ORL J Otorhinolaryngol Relat Spec 1996;58(5):288-294.
  • 8. Jokinen K, Palva T, Sutinen S, Nuutinen J. Acquired tracheobronchomalacia. Ann Clin Res 1077;9(2):52-57.
  • 9. Brody AS, Kuhn JP, Seidel FG, Brodsky LS. Airway evaluation in children with use of ultrafast CT: pitfalls and recommendations. Radiology 1991;178(1):181-184.
  • 10. Larici AR, del Ciello A, Maggi F, Santoro SI, Meduri B, Valentini V, Giordano A, Bonomo L. Lung abnormalities at multimodality imaging after radiation therapy for non-small cell lung cancer. Radiographics 2011;31(3):771-889.
  • 11. Choi YW, Munden RF, Erasmus JJ, Park KJ, Chung WK, Jeon SC, Park C-K. Effects of radiation therapy on the lung: radiologic appearances and differential diagnosis. Radiographics 2004; 24(4):985-997.
  • 12. Dutau H, Laroumagne S, Bylicki O, Vandemoortele T. Tracheobronchomalacia in adults: breakthroughs and controversies. Astoul P.Rev Mal Respir 2012;29(10):1198-1208.
  • 13. Carden KA, Boiselle PM, Waltz DA, Ernst A. Tracheomalacia and tracheobronchomalacia in children and adults: an in-depth review. Chest 2005;127(3):984-1005.
  • 14. Biswas A, Jantz MA, Sriram PS, Mehta HJ. Tracheobronchomalacia. Dis Mon 2017;63(10):287-302.
  • 15. Gangadharan SP, Mathew F. Thermoablative Techniques to Treat Excessive Central Airway Collapse. Thorac Surg Clin 2023;33(3):299-308.
  • 16. Lee KS, Sun MRM, Ernst A, Feller-Kopman D, Majid A, Boiselle PM. Comparison of dynamic expiratory CT with bronchoscopy for diagnosing airway malacia: a pilot evaluation. Chest 2007;131(3):758-764.
  • 17. Lee EY, Litmanovich D, Boiselle PM. Multidetector CT evaluation of tracheobronchomalacia. Radiol Clin North Am 2009;47(2):261-269.
  • 18. Majid A, Gaurav K, Sanchez JM, Berger RL, Folch E, Fernandez- Bussy S, Ernst A, Gangadharan SP. Evaluation of tracheobronchomalacia by 34 dynamic flexible bronchoscopy. A pilot study. Ann Am Thorac Soc 2014;11(6):951-955.
  • 19. Aquino SL, Shepard JA, Ginns LC, Moore RH, Halpern E, Grillo HC, McLoud TC. Acquired tracheomalacia, detection by expiratory CT scan. J Comput Assist Tomogr 2001;25(3):394-399.
  • 20. Pezzuto A, Ricci A, D’Ascanio M, Moretta A, Tonini G, Calabrò N, Minoia V, Pacini A, Paolis GD, Chichi E, Carico E, Tammaro A. Short-Term Benefits of Smoking Cessation Improve Respiratory Function and Metabolism in Smokers. Int J Chron Obstruct Pulmon Dis 2023;18:2861-2865.
  • 21. Santos Portela AM, Radu DM, Onorati I, Peretti M, Freynet O, Uzunhan Y, Jerbi S, Martinod E. Interventionnal bronchoscopy for the treatment of tracheobronchomalacia. Rev Mal Respir 2023;40(8):700-715.

İleri Evre Akciğer Kanseri Hastasında Radyoterapi Sonrası İlerleyen Erişkin Trakeobronkomalazi: Nadir Bir Olgu

Year 2024, Volume: 8 Issue: 2, 201 - 206, 30.08.2024
https://doi.org/10.29058/mjwbs.1460900

Abstract

Trakeobronkomalazi (TBM), sıklıkla zorlu ekspirasyon sırasında solunum semptomlarına ve komplikasyonlara yol açan trakea ve bronşların kollapsıdır. Radyoterapi (RT) erişkin TBM'nin nadir bir nedenidir.
Burada, skuamöz hücreli akciğer karsinomlu bir hastada palyatif RT'yi takiben ilerleyen ilk TBM vakasını sunuyoruz. TBM tanısı fiberoptik bronkoskopi ve toraks BT taramaları ile konuldu.
Palyatif RT'yi takiben nefes darlığı ve öksürüğü artan ileri evre akciğer kanserli hastalarda TBM de dikkate alınmalıdır.

References

  • 1. Nuutinen J. Acquired tracheobronchomalacia. A clinical study with bronchological correlations. Ann Clin Res 1977;9(6):350- 355.
  • 2. Murgu SD, Colt HG. Treatment of adult tracheobronchomalacia and excessive dynamic airway collapse: an update. Treat Respir Med 2006;5(2):103-115.
  • 3. Buitrago DH, Wilson JL, Parikh A, Majid A, Gangadharan SP. Current concepts in severe adult tracheobronchomalacia: evaluation and treatment. J Thorac Dis 2017;9(1):E57-E66.
  • 4. Murgu S, Colt H. Tracheobronchomalacia and excessive dynamic airway collapse. Clin Chest Med 2013;34(3):527-555.
  • 5. Kamran A, Baird CW, Jennings RW. Tracheobronchomalacia, Tracheobronchial Compression, and Tracheobronchial Malformations: Diagnostic and Treatment Strategies. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2020;23:53-61.
  • 6. Wright CD. Tracheobronchomalacia and expiratory collapse of central airways. Thorac Surg Clin 2018;28(2):163-166.
  • 7. Kano Y, Sakurai H, Shidara J, Toida S, Yasuda H. Histopathological and immunohistochemical studies of acquired tracheobronchomalacia: an autopsy case report. ORL J Otorhinolaryngol Relat Spec 1996;58(5):288-294.
  • 8. Jokinen K, Palva T, Sutinen S, Nuutinen J. Acquired tracheobronchomalacia. Ann Clin Res 1077;9(2):52-57.
  • 9. Brody AS, Kuhn JP, Seidel FG, Brodsky LS. Airway evaluation in children with use of ultrafast CT: pitfalls and recommendations. Radiology 1991;178(1):181-184.
  • 10. Larici AR, del Ciello A, Maggi F, Santoro SI, Meduri B, Valentini V, Giordano A, Bonomo L. Lung abnormalities at multimodality imaging after radiation therapy for non-small cell lung cancer. Radiographics 2011;31(3):771-889.
  • 11. Choi YW, Munden RF, Erasmus JJ, Park KJ, Chung WK, Jeon SC, Park C-K. Effects of radiation therapy on the lung: radiologic appearances and differential diagnosis. Radiographics 2004; 24(4):985-997.
  • 12. Dutau H, Laroumagne S, Bylicki O, Vandemoortele T. Tracheobronchomalacia in adults: breakthroughs and controversies. Astoul P.Rev Mal Respir 2012;29(10):1198-1208.
  • 13. Carden KA, Boiselle PM, Waltz DA, Ernst A. Tracheomalacia and tracheobronchomalacia in children and adults: an in-depth review. Chest 2005;127(3):984-1005.
  • 14. Biswas A, Jantz MA, Sriram PS, Mehta HJ. Tracheobronchomalacia. Dis Mon 2017;63(10):287-302.
  • 15. Gangadharan SP, Mathew F. Thermoablative Techniques to Treat Excessive Central Airway Collapse. Thorac Surg Clin 2023;33(3):299-308.
  • 16. Lee KS, Sun MRM, Ernst A, Feller-Kopman D, Majid A, Boiselle PM. Comparison of dynamic expiratory CT with bronchoscopy for diagnosing airway malacia: a pilot evaluation. Chest 2007;131(3):758-764.
  • 17. Lee EY, Litmanovich D, Boiselle PM. Multidetector CT evaluation of tracheobronchomalacia. Radiol Clin North Am 2009;47(2):261-269.
  • 18. Majid A, Gaurav K, Sanchez JM, Berger RL, Folch E, Fernandez- Bussy S, Ernst A, Gangadharan SP. Evaluation of tracheobronchomalacia by 34 dynamic flexible bronchoscopy. A pilot study. Ann Am Thorac Soc 2014;11(6):951-955.
  • 19. Aquino SL, Shepard JA, Ginns LC, Moore RH, Halpern E, Grillo HC, McLoud TC. Acquired tracheomalacia, detection by expiratory CT scan. J Comput Assist Tomogr 2001;25(3):394-399.
  • 20. Pezzuto A, Ricci A, D’Ascanio M, Moretta A, Tonini G, Calabrò N, Minoia V, Pacini A, Paolis GD, Chichi E, Carico E, Tammaro A. Short-Term Benefits of Smoking Cessation Improve Respiratory Function and Metabolism in Smokers. Int J Chron Obstruct Pulmon Dis 2023;18:2861-2865.
  • 21. Santos Portela AM, Radu DM, Onorati I, Peretti M, Freynet O, Uzunhan Y, Jerbi S, Martinod E. Interventionnal bronchoscopy for the treatment of tracheobronchomalacia. Rev Mal Respir 2023;40(8):700-715.
There are 21 citations in total.

Details

Primary Language English
Subjects Chest Diseases
Journal Section Case Report
Authors

Hülya Abalı 0000-0003-4041-7479

Seda Tural Önür 0000-0002-0657-0392

Aslı Biçen 0000-0002-7368-2714

Kaan Kara 0000-0001-5896-2497

Publication Date August 30, 2024
Submission Date March 29, 2024
Acceptance Date June 19, 2024
Published in Issue Year 2024 Volume: 8 Issue: 2

Cite

Vancouver Abalı H, Tural Önür S, Biçen A, Kara K. Adult Tracheobronchomalacia that Progressed Following Radiotherapy in an Advanced-stage Lung Cancer Patient: A Rare Case Report. Med J West Black Sea. 2024;8(2):201-6.

Medical Journal of Western Black Sea is a scientific publication of Zonguldak Bulent Ecevit University Faculty of Medicine.

This is a refereed journal, which aims at achieving free knowledge to the national and international organizations and individuals related to medical sciences in publishedand electronic forms.

This journal is published three annually in April, August and December.
The publication language of the journal is Turkish and English.