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A Case of Follicular Thyroid Carcinoma Emerging with Vertebral and Lung Metastases Twenty Years After the Thyroidectomy

Year 2015, Volume: 6 Issue: 23, 48 - 51, 30.09.2015
https://doi.org/10.17944/mkutfd.73198

Abstract

When the subjects are diagnosed with the follicular thyroid carcinoma, there are seen extra-thyroidal invasion in 25% of them, metastases in local lymph nodes in 5-10% of them and distant metastases in 10-20% of them. While 10-year survival rate is 8095% in the patients with differentiated thyroid carcinoma, this rate decreases to 40% in ones with distance metastases. Distance metastases are observed in 25% of the patients with follicular thyroid carcinoma over the age of 40. Follicular carcinoma frequently metastasizes to the lungs and bone. In this paper, a case is presented such that subtotal thyroidectomy was applied twenty years ago, the lung and bone metastases of follicular thyroid carcinoma were detected and any tumor tissue was not interestingly observed in complementary thyroidectomy in our center.

References

  • Malloy KM, Cunnane FM. Pathology and cytologic features of thyorid neoplasms. Surg Oncol Clin N Am 2008; 17(1): 57-70.
  • McHenry CR, Phitayakorn R. Follicular adenoma and carcinoma of the thyroid gland. Oncologist 2011;16(5):585-93.
  • Sillery JC, Reading CC, Charboneau JW, Henrichsen TL, Hay ID, Mandrekar JN. Thyroid follicular carcinoma: sonographic features of 50 cases. AJR Am J Roentgenol. 2010;194(1):44-54.
  • Witt RL. Initial surgical management of thyroid cancer. Surg Oncol Clin N Am 2008; 17(1): 71-91.
  • Shaha AR, Shah JP, Loree TR. Low-risk differentiated thyroid cancer: the need for selective treatment. Ann Surg Oncol 1997;4(4):328–33.
  • Witte J, Goretzki PE, Dieken J, Simon D, Röher HD. Importance of lymph node metastases in follicular thyroid cancer. World J Surg 2002;26(8):1017-22.
  • Cognetti DM, Pribitkin EA, Keane WM. Management of the neck in differentiated thyroid cancer. Surg Oncol Clin N Am 2008; 17(1): 157-173.
  • Pacini F, Schlumberger M, Dralle H, Elisei R, Smit JW, Wiersinga W. European Thyroid Cancer Task force. European consensus for the management of patients with differentiated thyroid carcinoma of the follicular epithelium. Eur J Endocrinol 2006;154(6):787-803
  • Shammas A, Degirmenci B, Mountz JM. 18F-FDG PET/CT in patients with suspected recurrent or metastatic well-differentiated thyroid cancer. J NuclMed 2007;48(2):221-6.
  • Durante C, Haddy N, Baudin E, Leboulleux S. Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma:benefits and limits of radioiodine therapy. J Clin Endocrinol Metab 2006;91(8) :2892-9.
  • Cho SW, Choi HS, Yeom GJ.Long-Term Prognosis of Differentiated Thyroid Cancer with Lung Metastasis in Korea and Its Prognostic Factors. Thyroid 2013; (8) :11.
  • Wexler JA. Approach to the thyroid cancer patient with bone metastases. J Clin Endocrinol Metab. 2011; 96(8) :2296-7.

TİROİDEKTOMİDEN YİRMİ YIL SONRA VERTEBRA VE AKCİĞER METASTAZI İLE ORTAYA ÇIKAN BİR TİROİD FOLLİKÜLER KARSİNOMU VAKASI

Year 2015, Volume: 6 Issue: 23, 48 - 51, 30.09.2015
https://doi.org/10.17944/mkutfd.73198

Abstract

Folliküler tiroid karsinomu tanısı konulan olguların %25’inde ekstra tiroidal invazyon, %5-10’unda lokal lenf bezlerine metastaz ve %10-20’sinde uzak metastaz görülmektedir. Differansiye tiroid karsinomalı hastalarda 10 yıllık sağ kalım oranı %80-95 iken, uzak metastazı olanlarda 10 yıllık sağ kalım oranı  %40’a düşmektedir. Folliküler tiroid karsinomlu 40 yaşın üzerindeki hastaların %25’inde uzak metastaz görülmektedir. Folliküler karsinom sıklıkla akciğer ve kemiğe metastaz yapar. Bu bildiride yirmi yıl önce subtotal tiroidektomi uygulanmış, merkezimizde folliküler tiroid karsinomunun akciğer ve kemik metastazı saptanan, ilginç olarak tamamlayıcı tiroidektomisinde tümör dokusu izlenmeyen bir olgu sunulmuştur.

References

  • Malloy KM, Cunnane FM. Pathology and cytologic features of thyorid neoplasms. Surg Oncol Clin N Am 2008; 17(1): 57-70.
  • McHenry CR, Phitayakorn R. Follicular adenoma and carcinoma of the thyroid gland. Oncologist 2011;16(5):585-93.
  • Sillery JC, Reading CC, Charboneau JW, Henrichsen TL, Hay ID, Mandrekar JN. Thyroid follicular carcinoma: sonographic features of 50 cases. AJR Am J Roentgenol. 2010;194(1):44-54.
  • Witt RL. Initial surgical management of thyroid cancer. Surg Oncol Clin N Am 2008; 17(1): 71-91.
  • Shaha AR, Shah JP, Loree TR. Low-risk differentiated thyroid cancer: the need for selective treatment. Ann Surg Oncol 1997;4(4):328–33.
  • Witte J, Goretzki PE, Dieken J, Simon D, Röher HD. Importance of lymph node metastases in follicular thyroid cancer. World J Surg 2002;26(8):1017-22.
  • Cognetti DM, Pribitkin EA, Keane WM. Management of the neck in differentiated thyroid cancer. Surg Oncol Clin N Am 2008; 17(1): 157-173.
  • Pacini F, Schlumberger M, Dralle H, Elisei R, Smit JW, Wiersinga W. European Thyroid Cancer Task force. European consensus for the management of patients with differentiated thyroid carcinoma of the follicular epithelium. Eur J Endocrinol 2006;154(6):787-803
  • Shammas A, Degirmenci B, Mountz JM. 18F-FDG PET/CT in patients with suspected recurrent or metastatic well-differentiated thyroid cancer. J NuclMed 2007;48(2):221-6.
  • Durante C, Haddy N, Baudin E, Leboulleux S. Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma:benefits and limits of radioiodine therapy. J Clin Endocrinol Metab 2006;91(8) :2892-9.
  • Cho SW, Choi HS, Yeom GJ.Long-Term Prognosis of Differentiated Thyroid Cancer with Lung Metastasis in Korea and Its Prognostic Factors. Thyroid 2013; (8) :11.
  • Wexler JA. Approach to the thyroid cancer patient with bone metastases. J Clin Endocrinol Metab. 2011; 96(8) :2296-7.
There are 12 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Case Report
Authors

Celil Usluogullari

Fevzi Balkan This is me

Elif Ozdemir This is me

Reyhan Ersoy This is me

Bekir Cakir This is me

Publication Date September 30, 2015
Submission Date September 29, 2015
Published in Issue Year 2015 Volume: 6 Issue: 23

Cite

Vancouver Usluogullari C, Balkan F, Ozdemir E, Ersoy R, Cakir B. TİROİDEKTOMİDEN YİRMİ YIL SONRA VERTEBRA VE AKCİĞER METASTAZI İLE ORTAYA ÇIKAN BİR TİROİD FOLLİKÜLER KARSİNOMU VAKASI. mkutfd. 2015;6(23):48-51.