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            <front>

                <journal-meta>
                                                                <journal-id>mmnsa</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Mathematical Modelling and Numerical Simulation with Applications</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2791-8564</issn>
                                                                                            <publisher>
                    <publisher-name>Mehmet YAVUZ</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.53391/mmnsa.2022.009</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Bioinformatics and Computational Biology</subject>
                                                            <subject>Applied Mathematics</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Biyoinformatik ve Hesaplamalı Biyoloji</subject>
                                                            <subject>Uygulamalı Matematik</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>An optimal control strategy and Grünwald-Letnikov finite-difference numerical scheme for the fractional-order COVID-19 model</article-title>
                                                                                                                                        </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-4076-9063</contrib-id>
                                                                <name>
                                    <surname>Ul Haq</surname>
                                    <given-names>Ihtisham</given-names>
                                </name>
                                                                    <aff>Department of Mathematics, University of Malakand, Chakdara Dir (L), 18000, Khyber Pakhtunkhwa</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-6920-3194</contrib-id>
                                                                <name>
                                    <surname>Ali</surname>
                                    <given-names>Nigar</given-names>
                                </name>
                                                                    <aff>Department of Mathematics, University of Malakand, Chakdara Dir (L), 18000, Khyber Pakhtunkhwa</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-5769-4320</contrib-id>
                                                                <name>
                                    <surname>Nisar</surname>
                                    <given-names>Kottakkaran Sooppy</given-names>
                                </name>
                                                                    <aff>Department of Mathematics, College of Arts and Science, Prince Sattam bin Abdulaziz University</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20220630">
                    <day>06</day>
                    <month>30</month>
                    <year>2022</year>
                </pub-date>
                                        <volume>2</volume>
                                        <issue>2</issue>
                                        <fpage>108</fpage>
                                        <lpage>116</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20220417">
                        <day>04</day>
                        <month>17</month>
                        <year>2022</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20220620">
                        <day>06</day>
                        <month>20</month>
                        <year>2022</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2021, Mathematical Modelling and Numerical Simulation with Applications</copyright-statement>
                    <copyright-year>2021</copyright-year>
                    <copyright-holder>Mathematical Modelling and Numerical Simulation with Applications</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>In this article, a mathematical model of the COVID-19 pandemic with control parameters is introduced. The main objective of this study is to determine the most effective model for predicting the transmission dynamic of COVID-19 using a deterministic model with control variables. For this purpose, we introduce three control variables to reduce the number of infected and asymptomatic or undiagnosed populations in the considered model. Existence and necessary optimal conditions are also established. The Grünwald-Letnikov non-standard weighted average finite difference method (GL-NWAFDM) is developed for solving the proposed optimal control system. Further, we prove the stability of the considered numerical method. Graphical representations and analysis are presented to verify the theoretical results.</p></abstract>
                                                                                    
            
                                                            <kwd-group>
                                                    <kwd>Caputo fractional derivative</kwd>
                                                    <kwd>  optimal control strategy</kwd>
                                                    <kwd>  Grünwald-Letnikov numerical method</kwd>
                                                    <kwd>  stability analysis</kwd>
                                            </kwd-group>
                                                        
                                                                                                                                                    </article-meta>
    </front>
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