mucosa

Mucosa

2651-2750

Doğu Karadeniz Deri ve Zührevi Hastalıklar Derneği

10.33204/mucosa.654798

Clinical Sciences

Klinik Tıp Bilimleri

Retrospective evaluation of 106 Behçet’s disease patients in Giresun province

Giresun ilindeki 106 Behçet hastasının retrospektif değerlendirilmesi

https://orcid.org/0000-0002-3052-5014

Akşan

Burak

GİRESUN İLİ UYGULAMA VE ARAŞTIRMA MERKEZİ

https://orcid.org/0000-0001-7886-1060

Kulaklı

Sevgi

GİRESUN İLİ UYGULAMA VE ARAŞTIRMA MERKEZİ

https://orcid.org/0000-0001-8628-6107

Oğuz

Işıl Deniz

GİRESUN İLİ UYGULAMA VE ARAŞTIRMA MERKEZİ

03 31 2020

3 1 12 17 12 04 2019 03 23 2020

2018

Mucosa

Background Behçet’s disease (BD) is a multisystem inflammatory disorder which is an important cause of morbidity in Turkey.Objective We aimed to investigate the demographical and clinical features of patients with BD followed up in our department in Faculty of Medicine in Giresun University Training and Research Hospital.Methods The hospital records of patients with BD who attended the dermatology department between 2006-2019 were retrospectively evaluated. One hundred and six patients who met the diagnostic criteria of International Study Group for BD were included in the study. The clinical and demographic characteristics, including the age of onset, disease duration, mucocutaneous findings and systemic involvements were recorded.Results Of the 106 patients in the study, 64 (60.4%) were female, 42 (39.6%) were male, and the female-to-male ratio was 1.52:1. The median age at the onset of the disease was 38 years, and the median disease duration was 9 years (range 1-40 years). The most common finding was recurrent oral ulcers (100%) followed by genital ulcers (86.6%), ocular involvement (52.8%), erythema nodosum (49.1%), articular involvement (45.3%), papulopustular lesions (34%), positive pathergy test (21.7%), vascular involvement (14.2%), gastrointestinal involvement (9.4%), neurologic (2.8%) and genitourinary involvement (2.8%). Papulopustular lesions were seen statistically significantly more frequent in men (P=0.047).Conclusion In our study, we presented the demographical and clinical features of patients with BD in a single center in Giresun. Major findings were mucocutaneous ones and most common extracutaneous involvements were eyes and joints.

Amaç Behçet hastalığı (BH) Türkiye’de önemli morbiditelere neden olan, multisistemik inflamatuvar bir hastalıktır. Bu çalışmada Giresun Üniversitesi Tıp Fakültesi Eğitim ve Araştırma Hastanesi dermatoloji kliniğinde BH tanısı ile takip edilen hastaların demografik ve klinik özelliklerinin belirlenmesi amaçlandı. Yöntem 2006-2019 yılları arasında hastanemiz dermatoloji kliniğinde BH tanısı ile izlenen hastaların kayıtları geriye dönük olarak incelendi. Uluslararası Behçet hastalığı Çalışma Grubu’nun tanı kriterlerini karşılayan toplam 106 hasta çalışmaya dâhil edildi. Başlangıç yaşı, hastalık süresi, mukokütanöz bulgular ve sistemik tutulumlar dâhil olmak üzere klinik ve demografik özellikler kaydedildi.Bulgular Çalışmaya alınan 106 hastanın 64’ü kadın (%60.4), 42’si erkekti (%39.6). Kadın/erkek oranı 1.52:1 idi. Ortalama başlangıç yaş ortancası 38 yaş, hastalık süresi ortancası 9 yıl (1-40) olarak saptandı. En sık görülen klinik bulgu tekrarlayan oral ülserlerdi, hastaların tamamında mevcuttu. Oral ülserleri sırasıyla genital ülser (%81.1), göz tutulumu (%52.8), eritema nodozum (%49.1), eklem tutulumu (%45.3), papülopüstüler lezyonlar (%34), pozitif paterji testi (%21.7), damar tutulumu (%14.2), gastrointestinal tutulum (%9.4), nörolojik (%2.8) ve genitoüriner tutulum (%2.8) takip etmekteydi. Erkeklerde papülopüstüler lezyon sıklığı kadınlara göre anlamlı oranda daha yüksek saptandı (P=0.047).Sonuç Çalışmamızda Giresun’da tek merkezli olarak takip edilen Behçet hastalarının demografik ve klinik verileri sunuldu. Mukokütanöz bulguların ön planda olduğu hastalarda göz ve eklem en sık tutulan deri dışı organlar olarak saptandı.

Behçet’s disease epidemiology demographical characteristics turkey

Behçet hastalığı demografik özellikler epidemiyoloji Türkiye

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