mucosa Mucosa 2651-2750 Doğu Karadeniz Deri ve Zührevi Hastalıklar Derneği 10.33204/mucosa.706681 Clinical Sciences Klinik Tıp Bilimleri Çocuklarda peptik ülser hastalığı Peptic ulcer disease in children https://orcid.org/0000-0002-5142-8168 Güven Burcu Karadeniz Technical University https://orcid.org/0000-0003-3069-2872 Sağ Elif Karadeniz Technical University Usta Deniz Karadeniz Technical University İssi Fatma Karadeniz Technical University https://orcid.org/0000-0003-4071-6129 Çakır Murat Karadeniz Technical University 03 31 2020 3 1 18 22 03 20 2020 03 27 2020 Copyright © 2018, Mucosa 2018 Mucosa

Amaç Çocukluk çağında peptik ülserlere ilişkin veriler yetersizdir. Bu çalışmanın amacı, çocuklarda peptik ülser hastalığı (PÜH) sıklığını ve özelliklerini saptamak, H.pylori ile diğer nedenlere bağlı PÜH’ nı karşılaştırmaktır.Yöntem Haziran 2008 ile Haziran 2019 tarihleri arasında endoskopi yapılan pediatrik hastalar incelendi. PÜH olan her hasta için yaş, cinsiyet, klinik bulgular, peptik ülserin (PÜ) yeri, histopatolojik olarak H.pylori varlığı ve hemoglobin değerleri kaydedildi. Hastalar H.pylori’ ye bağlı ve diğer nedenlere bağlı PÜH olarak ikiye ayrıldı. İki grup karşılaştırıldı.Bulgular 6216 hastanın 60’ına (% 0.98) PÜH tanısı konuldu. Altmış hastanın yaş ortalaması 10.59±4.89 yıl olup, 32 (%53.3)’ i erkek, 28 (%46.6)’ i kızdı. En sık şikâyet karın ağrısıydı (n=40; %60.6). Altmış hastanın 12 (%20)’ sinde histopatolojik olarak H.pylori tespit edildi. İki grup arasında yaş, cinsiyet, klinik bulgular, anemi veya PÜ’in yeri açısından fark yoktu.Sonuç Peptik ülser hastalığı çocuk çağında nadir görülür. H.pylori ve diğer nedenlere bağlı PÜH arasında klinik bulgular, anemi ve PÜ’ in yeri açısından fark yoktur. İki grubun ayrımı için tüm hastalardan biyopsi alınmalıdır.

Background Data on peptic ulcers in childhood are insufficient. The aim of this study is to define the frequency and characteristics of peptic ulcer disease (PUD) in children and to compare with PUD due to H.pylori infection and the others.Methods Pediatric patients that underwent upper gastrointestinal endoscopy between July 2008 and July 2019 were examined. Age, gender, clinical presentation, location of peptic ulcer (PU), presence of H.pylori histopathologically and hemoglobine values were recorded for each paient with PUD from the hospital file records. Patients were divided into two groups as patients with PUD associated H.pylori and patients with PUD associated with other etiologies. Then two groups were compared.Results Sixty (0.98%) of 6216 patients were diagnosed with PUD. Sixty patients comprised 32 (53.3%) male and 28 (46.6%) female with a mean age of 10.59±4.89 years. The most common complaint was abdominal pain (n=40; %60.6). H.pylori was detected in 12 (20%) of 60 patients histopathologically. There was no difference between two groups for age, gender, clinical presentation, anemia or location of PU.Conclusion PUD is a rare disorder in childhood. There is no difference between H.pylori related PUD and the others for clinical presentation, anemia or location of PU. For the discrimination of two groups, biopsy should be taken in all patients.

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