Laugier-Hunziker sendromu: Nadir bir olgu sunumu ve literatürün gözden geçirilmesi

Year 2021, , 50 - 55, 30.06.2021

Hande Ermiş

https://doi.org/10.33204/mucosa.948546

Abstract

Laugier-Hunziker sendromu, mukokutanöz lentijinler ve melanonişiyle seyreden nadir görülen kalıtsal bir pigment bozukluğudur. Bu sendroma, altta yatan bir malignite ya da sistemik hastalıkla henüz ilişkilendirilmediğinden benign olarak yaklaşılır. Peutz-Jeghers, Cronkhite-Canada sendromu gibi malignite sendromları ve Addison hastalığı, ilaçlar gibi hiperpigmentasyona yol açan durumlar da benzer mukokutanöz bulgularla seyrettiğinden, hastaların bu durumlar dışlanarak değerlendirilmesi önemlidir.

Keywords

Laugier-Hunziker sendromu, mukokutanöz hiperpigmentasyon, melanonişi

Laugier-Hunziker syndrome: a rare case report and review of the literature

Abstract

Laugier-Hunziker syndrome is a rare, hereditary pigmentary disorder characterized by mucocutaneous lentiginous lesions and melanonychia. The condition is regarded as benign since underlying malignancies or systemic disorders were not reported. Since various malignancy syndromes including Peutz-Jeghers and Cronkhite-Canada syndrome and systemic cause of hyperpigmentation such as Addison disease and drugs are presented with similar mucocutaneous findings, it is of paramount importance to assess the patients to exclude aforementioned conditions.

Keywords

Laugier-Hunziker Syndrome, mucocutaneous hyperpigmentation, melanonychia

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