Trakea Yerleşimli Adenoid Kistik Karsinom: Olgu Sunumu

Year 2021, Volume: 8 Issue: 3, 227 - 229, 28.12.2021

Deniz Kütri Alaattin Özen Suzan Şaylısoy

https://doi.org/10.47572/muskutd.781508

Abstract

Adenoid Kistik Karsinom, 100000’de 0.1-0.26 görülme insidansı ile oldukça nadir görülen bir hastalıktır. Trakeanın ikinci en sık görülen primer malignitesi olmakla birlikte cerrahi rezeksiyon esas tedavi yöntemidir. Ancak cerrahi olamayacak hastalarda ya da cerrahi sonrası mikroskobik/makroskobik rezidü hastalık varlığında radyoterapi önerilmektedir. Nadir görülen bir tümör olması ve cerrahi sınır pozitifliği nedenleri ile küratif radyoterapi uyguladığımız 38 yaşında kadın olguyu sunmayı amaçladık.

Keywords

Adenoid Kistik Karsinom, Radyoterapi, Trakea

Tracheal Adenoid Cystic Carcinoma: Case Report

Abstract

Adenoid Cystic Carcinoma is an extremely rare disease with an incidence of 0.1-0.26 per 100000. It is the second most common primary malignancy of the trachea. Surgical resection is the main treatment method. However, radiotherapy treatment is recommended in patients who cannot be operated on or in the presence of postoperative microscopic/macroscopic residue. We aimed to present this rare case with a thirty-eight year old woman to whom we applied a curative radiotherapy due to the rarity of the tumor and a positive surgical margin.

Keywords

Adenoid Cystic Carcinoma, Radiotherapy, Trachea

References

• 1. Macchiarini P. Primary tracheal tumours. Lancet Oncol. 2006;7:83-91.
• 2. Bhattacharyya N. Contemporary staging and prognosis for primary tracheal malignancies: a population-based analysis. Otolaryngol Head Neck Surg. 2004;131:639-42.
• 3. Grillo HC. Surgery of the Trachea and Bronchi. Pmph USA Ltd., Hamilton, Ontario, 2004.
• 4. Shadmehr MB, Farzanegan R, Graili P, et al. Primary major airway tumors; management and results. Eur J Cardiothorac Surg. 2011;39:749-54.
• 5. Thotathil ZS, Agarwal JP, Shrivastava SK, Dinshaw KA. Primary malignant tumors of the trachea - the Tata Memorial Hospital experience. Med Princ Pract. 2004;13(2):69-73.
• 6. Calzada AP, Miller M, Lai CK, et al. Adenoid cystic carcinoma of the airway: a 30-year review at one institution. Am J Otolaryngol. 2012;33:226-31.
• 7. Li W, Hua W, Yan FG, Shen HH, Xu H. Adenoid cystic carcinoma of trachea: a case report and review of literature. Chin Med J (Engl). 2012;125(12):2238-9.
• 8. Kim D, Hwang Y, Choi S, et al. A case of tracheal adenoid cystic carcinoma in a worker exposed to rubber fumes. Ann Occup Environm Med. 2013;25:22.
• 9. Wingren G, Axelson O. Cancer incidence and mortality in a Swedish rubber tire manufacturing plant. Am J Ind Med. 2007;50(12):901-9.
• 10. Vermeulen R, Bos RP, de Hartog J, et al. Mutagenic profile of rubber dust and fume exposure in two rubber tire companies. Mutat Res. 2000;468(2):165-71.
• 11. Ahn Y, Chang H, Lim YS, et al. Primary tracheal tumors: review of 37 cases. J Thorac Oncol. 2009;4:635-8.
• 12. Haresh KP, Prabhakar R, Rath GK, et al. Adenoid cystic carcinoma of the trachea treated with PET-CT based intensity modulated radiotherapy. J Thorac Oncol. 2008;3:793-5.
• 13. Grillo HC, Mathisen DJ. Primary tracheal tumors: treatment and results. Ann Thorac Surg. 1990;49:69-77.
• 14. Qi D, Feng L, Li J, Liu B, Zhang Q. Primary adenoid cystic carcinoma of the trachea with thyroid invasion: a case report and literature review. Onco Targets Ther. 2016;9:6291-6.
• 15. Sarkar M, Madabhavi I, Niranjan N, Dogra M. Auscultation of the respiratory system. Ann Thorac Med. 2015;10(3):158-68.
• 16. Lewis S, Earley M, Rosenfeld R, Silverman J. Systematic review for surgical treatment of adult and adolescent laryngotracheal stenosis. Laryngoscope. 2017;127(1):191-8.
• 17. Naim A, Hajjij A, Abbad F, Rami A, Essaadi M. Rare location of head and neck adenoid cystic carcinoma. Pan Afr Med J. 2019;34:33.
• 18. Desai HM, Thakare R, Amonkar GP, Karkhanis V, Joshi JM. Adenoid cystic carcinoma of the trachea. Indian J Pathol Microbiol. 2015;58(4):516-8.
• 19. Kwak SH, Lee KS, Chung MJ, et al. Cystic carcinoma of the airways: helical CT and histopathologic correlation. AJR Am J Roentgenol. 2004;183:277-81.
• 20. Compeau CG, Keshavjee S. Management of tracheal neoplasms. Oncologist. 1996;1:347-53.
• 21. Azar T, Abdulkarim FW, Tucker HM. Adenoid cystic carcinoma of trachea. Laryngoscope. 1998;108:1297-300.
• 22. Gilbert RW, Keshavjee S. Tumors of the cervical trachea. In: Myers NJ, Hanna HYE, Myers NE (eds) Cancer of the Head and Neck. Wolters Kluver Livingstone, Alphen aan den Rijn, The Netherlands, pp 500-22,1981.
• 23. Varela P, Pio L, Brandigi E, et al. Tracheal and bronchial tumors. J Thorac Dis. 2016;8(12):3781-6.
• 24. Muller A, Stockamp B, Schnabel T. Successful primary radiation therapy of adenoid cystic carcinoma of lung. Oncology. 2000;58:15-7.
• 25. Haddad RI, Posner MR, Busse PM, et al. Chemoradiotherapy for adenoid cystic carcinoma: preliminary results of an organ sparing approach. Am J Clin Oncol. 2006;29(2):153-7
• 26. Regnard JF, Fourquier P, Levasseur P. Results and prognostic factors in resections of primary tracheal tumors: a multicenter retrospective study. The French society of cardiovascular surgery. J Thorac Cardiovasc Surg. 1996;111:808-13.
• 27. Gaissert HA, Grillo HC, Shadmehr MB, et al. Long-term survival after resection of primary adenoid cystic and squamous cell carcinoma of the trachea and carina. Ann Thorac Surg. 2004;78;1896-7.
• 28. Maziak DE, Todd TR, Keshavjee SH, et al. Adenoid cystic carcinoma of the airway: thirty-two-year experience. J Thorac Cardiovasc Surg. 1996;112:1522-31.