Study on The Frequency of Antibiotic Use Before Diagnosis in Granulomatous Mastitis

Year 2024, Volume: 11 Issue: 3, 187 - 193, 18.12.2024

Göknur Yapar Toros , Gamze Kiziltan

https://doi.org/10.47572/muskutd.1482193

Abstract

This retrospective cohort study compiled data from 69 patients pathologically diagnosed with granulomatous mastitis between 2015 and 2020. Patient demographics, whether they were taking antibiotics before diagnosis, the type and duration of antibiotic use, the time elapsed between pathologic diagnosis and initiation of treatment, the presence of a specific factor in microbiologic tests, the type of treatment after diagnosis, and the recovery period were recorded. The mean age was 34.58±7.30 years. It was found that 94.2% (n=65) of patients had taken empirical antibiotics before diagnosis.Seventy-one percent of the patients (n=53) had taken at least two different antibiotics.The mean time to pathological diagnosis was 12.7 months. Empiric antibiotic treatments, often given until the diagnosis of granulomatous mastitis is made pathologically, prolong the diagnostic process. It would be more appropriate to prioritize diagnostic testing to avoid unnecessary and long-term antibiotic use in these patients.

Keywords

Empiric Treatment, Antibiotic, Idiopathic, Granulomatous Mastitis, Treatment Management

Granülomatöz Mastitte Tanı Öncesi Antibiyotik Kullanım Sıklığı Üzerine Bir Çalışma

Abstract

Bu retrospektif kohort çalışmasında 2015-2020 yılları arasında granülomatöz mastit tanısı almış 69 hastaya ait veriler derlenmiştir. Hastalara ait demografik veriler, tanıdan önce antibiyotik alıp almadıkları, antibiyotik kullanımının türü ve süresi, patolojik tanı ile tedavi başlangıcı arasında geçen süre, mikrobiyolojik testlerde belirli bir faktörün varlığı, tanıdan sonra tedavi türü ve iyileşme süresi kaydedildi. Ortalama yaş 34.58±7.30 yıldı. Hastaların %94.2'sinin (n=65) tanıdan önce ampirik antibiyotik aldığı bulundu. Hastaların %71'i (n=53) en az iki farklı antibiyotik almıştı. Patolojik tanıya kadar geçen ortalama süre 12.7 aydı. Genellikle granülomatöz mastit tanısı patolojik olarak konulana kadar verilen ampirik antibiyotik tedavileri tanı sürecini uzatır. Bu hastalarda gereksiz ve uzun süreli antibiyotik kullanımının önüne geçmek için tanısal testlere öncelik verilmesi daha uygun olacaktır.

Keywords

Ampirik Tedavi, Antibiyotik, İdiyopatik, Granulomatöz Mastit, Tedavi Yönetimi

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