Tiroid Nodüllerinde Malign ve Benign Ayrımında Difüzyon Ağırlıklı Manyetik Rezonans İncelemenin Yeri

Year 2019, Volume: 7 Issue: 2, 47 - 52, 27.08.2019

Ömer Özçağlayan Tuğba İlkem Kurtoğlu Özçağlayan Ahmet Mesrur Halefoğlu

Abstract

Öz

Amaç: Bu çalışmanın amacı,  Difüzyon Ağırlıklı Manyetik Rezonans
Görüntülemenin (DAMRG) tiroid nodüllerinde malign-benign ayrımındaki yerini
araştırmak olacaktır.

Material-Metot: Çalışmaya tiroid nodülü ve patolojik
tanısı olan 39 hasta ve 40 nodül dahil edildi. İzlenen nodüller, DAMRG  ile incelendi ve elde edilen Apparent
Diffusion Coefficient (ADC) değerleri ve patolojik sonuçlar arasındaki ilişki
istatistiksel olarak değerlendirildi.

Bulgular: Nodüllerin 9’u malign, 31’i benign
karakterdeydi. Malign ve benign nodüllerin ortalama ADC değerleri  sırasıyla (1,60±0,29)x10⁻³
sn/mm²)ve (2,14±0,39)x10⁻³ sn/mm²)  bulundu. Malign ve benign ADC değerleri
arasında anlamlı istatistiksel farklılık izlendi (p<0,001). Receiver
Operator Coefficient (ROC) analizi ile malign nodüllerde cut-off değer 1,67x10⁻³
sn/mm² olarak hesaplandı.

Sonuç: ADC değerleri , benign ve malign tiroid
nodüllerini ayırmak için non-invaziv bir tanı metodu olarak kullanılabilir.

Abstract

Objective: The aim of this study was to
investigate the role of the Diffusion Weighted Imaging (DWI) sequences of
Magnetic Resonance Imaging (MR) in diagnosis of malignant and benign nodules of
thyroid nodules.

Matherial/Method: Thirty nine patients  and fourty nodules were enrolled to the
study. The observed nodules were examined with DWI. Relationship between
obtained Apparent Diffusion Coefficient (ADC) values and pathological results
were statistically evaluated.

Results: There were 9 malignant and 31 benign
nodules. Mean ADC values were evaluated (1.60±0.29)x10⁻³
sn/mm²  for malignant nodules , and
(2.14±0.39)x10⁻³ sn/mm²)  for benign nodules, respectively. There was a
statistical difference between ADC values of malignant and benign nodules
(p<0.001).  The ADC cut-off value of
malignant nodules was evaluated  1.67x10⁻³
sn/mm² with Receiver Operator Coefficient (ROC) analysis.

Conclusion: ADC values might be used as a
non-invasive diagnostic tool for discriminating the malignant and benign
thyroid nodules.

Keywords

difüzyon ağırlıklı MRG, tiroid nodülü, kanser

References

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