Hipotiroidizm

Year 2012, Volume: 29 Issue: 4S, 301 - 308, 07.05.2013

Hulusi Atmaca

https://doi.org/10.5835/jecm.omu.29.s4.017

Abstract

Hipotiroidizm endokrin pratiğinde en sık karşılaşılan hastalıklardan biridir. Hipotiroidizm, perifer dokuda tiroit hormon etkisinin azalması olarak tanımlanabilir. Vakaların büyük çoğunluğu tiroit bezinin hormon sentez ve salgılanmasının bozulması sonucunda gelişir. Sensitif biyokimyasal testlerin ve etkin tedavi imkanlarının mevcudiyeti bu endokrin hastalığın tanı ve tedavisini kolaylaştırmıştır. Bu makalede hipotiroidinin epidemiyolojisi, etyolojisi, klinik prezentasyonu, tanı ve tedavisi ele alınacaktır.

J. Exp. Clin. Med., 2012; 29:S301-S308

Hypothyroidism

Hypothyroidism is one of the most common disorders encountered in an endocrine practice. Hypothyroidism results from reduced thyroid hormone actions at the peripheral tissues. This reduction in thyroid hormone action is, in the vast majority of cases, secondary to reduced thyroid hormone synthesis and secretion by the thyroid gland. The availability of sensitive biochemical tests and effective therapies have simplified the diagnosis and management of this endocrine condition. This article reviews the epidemiology, etiology, clinical presentation, diagnosis, and treatment of hypothyroidism.

Keywords

Primer hipotiroidizm, Hashimoto tiroiditi, Santral hipotiroidizm, Subklinik hipotiroidizm, Miksödem koması, Tiroksin

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