Thorax computed tomography findings and mortality analysis of a localized outbreak of H1N1 pneumonia in east Part of Turkey in 2013

Year 2013, Volume: 30 Issue: 4, 339 - 344, 05.02.2014

Servet Kayhan Aziz Gümüş Halit Çınarka Sabri Oğullar Ayşe Ertürk Ünal Şahin

Abstract

There in we report a local outbreak of H1N1 pneumonia in east part of (Blacksea region) of Turkey. A total of 118 patients admitted to our emergency department with the similar complaints of malaise, high fever, myalgia, cough and dyspnea between December 2012 and April 2013. The diagnosis of H1N1 virus infection was confirmed in 21 hospitalized patients with pneumonia by using real-time polymerase chain reaction method. Five of the 21 patients died due to acute respiratory distress syndrome (ARDS) in a few days. We investigated the radiological manifestations and the risk factors for the mortality of the patients with influenza A (H1N1) virus related pneumonia.

J. Exp. Clin. Med., 2013; 30:339-344

Keywords

Computed tomography; H1N1 pandemic; influenza; mortality

References

• Akram, A.R., Chalmers, J.D., Hill, A.T., 2011. Predicting mortality with severity assessment tools in out-patients with community-acquired pneumonia. Q.J.M. 104, 871-879.
• Capelozzi, V.L., Parra, E.R., Ximenes, M., Bammann, R.H., Barbas, C.S., Duarte, M.I., 2010. Pathological and ultrastructural analysis of surgical lung biopsies in patients with swine-origin influenza type A/H1N1 and acute respiratory failure. Clinics (Sao Paulo). 65, 1229-1237.
• Li, M., Zhu, J.B., Chen, G.Q., Yang, W.Y., Tao, C., Wang, X.H., 2011. Influenza A (H1N1) pneumonia: An analysis of 63 cases by chest CT. Chin. Med. J. 124, 2669-2673.
• Marcos M.A., Esperatti, M., Torres, A. 2009. Viral pneumonia. Curr. Opin. Infect. Dis. 22, 143-147.
• Perez-Padilla, R., de la Rosa-Zamboni, D., Ponce de Leon, S., Hernandez, M., Quinones-Falconi, F., Bautista, E., Ramirez-Venegas, A., Rojas- Serrano, J., Ormsby, C.E., Corrales, A., Higuera, A., Mondragon, E., Cordova-Villalobos, J.A., INER Working Group on Influenza et al. 2009. Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico. N. Engl. J. Med. 361, 680-689.
• Riquelme, R., Torres, A., Rioseco, M.L., Ewig, S., Cilloniz, C., Riquelme, M., Inzunza, C., Polverino, E., Gomez, Y., Marcos, M.A., Contreras, C., Gabarrus, A., Fasce, R., 2011. Influenza pneumonia: A comparison between seasonal influenza virus and the H1N1 pandemic. Eur. Respir. J. 38, 106-111.
• Shaham, D., Bogot, N.R., Aviram, G., Guralnik, L., Lieberman, S., Copel, L., Sosna, J., Moses, A.E., Grotto, I., Engelhard, D., 2011. Severe influenza A (H1N1): the course of imaging findings. Isr. Med. Assoc. J. 13, 591-596.
• Woodhead, M., Welch, C.A., Harrison, D.A., Bellingan, G., Ayres, J.G. 2006. Community-acquired pneumonia on the intensive care unit: secondary analysis of 17,869 cases in the ICNARC Case Mix Programme Database. Crit. Care. 10, 1.
• World Health Organization. 2009. Outbreak of swine origin influenza A (H1N1) virus infection-Mexico, March-April 2009. http//www.who.int, MMWR Morb Mortal Wkly Rep. 58, 467. September 2011.