Research Article
PDF Zotero Mendeley EndNote BibTex Cite

Çocukluk Çağı Zehirlenmelerinin Retrospektif Analizi

Year 2019, Volume 41, Issue 2, 173 - 181, 01.04.2019
https://doi.org/10.20515/otd.392617

Abstract

Çocukluk çağı zehirlenmeleri acil servise başvuruların önemli nedenleri arasındadır. Bu çalışmada hastalarımızda görülen çocukluk çağı zehirlenmelerinin epidemiyolojik ve klinik özelliklerinin retrospektif olarak belirlenmesi amaçlandı. Bu çalışmada 01.01.2011 ile 14.06.2015 tarihleri arasında hastanemiz çocuk acil servisine zehirlenme nedeniyle getirilen 1168 olgu değerlendirildi. Zehirlenmelerin yaş gruplarına göre dağılımına bakıldığında en sık 13 ay-48 ay  grubunda (%44.18) olduğu görüldü.   Zehirlenme etkenlerine bakıldığı zaman en sık nedenin 545 vaka ile ilaçlar nedenli olduğu görüldü(%47.9). İkinci sırada  283 vaka sayısı (%24.9) ile karbonmonoksit zehirlenmeleriyer almaktaydı.  Zehirlenmeye neden olan ilaç etkenleri arasında ilk sırada  127 vaka (%21,67) ile analjezik/antipiretik ve kas gevşeticiler;  %20,3 ‘lük oran ile çoklu ilaç alımları ikinci sırada; duygu durum düzenleyiciler  de üçüncü sırada yer almakta idi. Duygu durum düzenleyiciler arasında en çok Trisiklik antidepresanlar  ile olan zehirlenme etkenlerine rastladık.  Zehirlenme etkeni olan maddelerin alınış yollarına bakıldığında; 792’sinde sindirim yoluyla (%67,8), 301’inde solunum yoluyla (%25,7) alındığı bulundu. Çalışmamızda zehirlenme etkenleri olarak ilaçlar birinci sırada yer almakta idi. Daha önce ki Türkiye çalışmalarından farklı olarak; Opioid analjezikler ve anti neoplastik ajanlar ile zehirlenmelere de rastlanıldı. Çocukluk çağı zehirlenmeleri genelde sekelsiz atlatılsa bile hala acil servis başvurularında önemli bir yer tutmaktadır. 

References

  • Uziel Y, Adler A, Aharonowitz G, Franco S, Fainmesser P, Wolach B.” Un Intentional Childhood Poisoning in the Sharon Area in Israel.” Pediatric Emergency Care 2005;21(4):248-2512. Kavalcı C, Demir A, Arslan ED, Yilmaz F, Durdu T, Yel C, Gülsüm et all.”Adult Poisoning Cases in Ankara: Capital City of Turkey” International Journal of Clinical Medicine 2012;3-7A,Article ID:26339 DOI:10.4236/ijcm.2012.37A129 3. J. Kristinsson, R. Palsson, G. A. Gudjonsdottır, M. Blondal, S. Gudmundsson and C. P. Snook, “Acute Poisonings in Iceland: A Prospective Nationwide Study,” Clinical Toxicology, Vol. 46, No. 2, 2008, pp. 126-132. doi:10.1080/155636507014382684. Uludağ Ö, Tutak A, Doğukan M, Kaya R, Tutak AŞ, Çelik M “Characteristics of poisoningcases in Adiyaman City” Dicle Medical Journal 2015;42(3)284-2885. Akbay-Öntürk Y, Uçar B.”Retrospective Analysis of Childhood Poisoning at Eskişehir Region “ Journal of Child Health Disease 2003; 46:103-13. ISSN: 0010 - 01616. Kırel B, Unluoglu I, Dogruel N, Koçak K, “Retrospective Analysis of Childhood Poisoning at Eskişehir Region” Turkiye Klinikleri J Med Sci 2000;9:158-163. ISSN: 1300-0292 7. Şahin S, Carman KB, Dinleyici EC, “AcutePoisoning in children; Data of a Pediatric Emergency Unit”, Iran J Ped. Dec 2011;21(4);479-484.8. Mintegi S, Fernandez A, Alustiza J, Canduela V, Mongil I, Caubet I et all .” Emergency Visits for Childhood Poisoning: A 2 Year Prospective Multicenter Survey in Spain.” Pediatric Emergency Care 2006;22(5):334-8.9. Burillo- Putze G, Munne P, Duenas A, et al. “National Multicentre Study of Accute İntoxication İn Emergency Departments of Spain.” European Journal of Emergency Medicine 2003;10(2):101-4. 10. Dereci S, Koca T, Gençer A, Serdaroğlu F, Akçam M. “ Evaluation of Childhood Poisoning in Isparta Region “Dicle Medical Journal / 2015; 42 (3): 319-325doi: 10.5798/diclemedj.0921.2015.03.058211. Kelebek F , Satar S , Kozacı N , Açıkalın A , Gülen M , Acehan S “Emergency Medicine Admissions of Pediatric Intoxicated Cases” The Journal of Academic Emergency Medicine “2014; 13: 67-7012. Eldridge DL, Eyk JV, Kornegay C. “Pediatric Toxicology” Emergency Medicine Clin North Am 2007;15:283-30813. Demirgan EB, Erol M, Demirgan S, Yiğit Ö, Türkay M. Retrospective Evaluation of Drug Poisoning Cases Referring to Pediatric Emergency Policlinic”, The Medical Journal of Okmeydanı Training and Resarch Hospital 30(3):128-134, 2014 doi:10.5222/otd.2014.12814. Litovitz TL, Klein-Schwartz W, White S, Cobaugh DJ, Youniss.”1999 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System.” Am. J. Emerg. Med. 2000;18(5):517–574.15. Özdemir R, Bayrakci B, O Tekşam, Yalçın B, Kale G ” Thirty-threeyear experience on childhood poisoning. “The Turkish Journal of Pediatrics, 2012;54:251-259.16. Yakar B “The Familial Factors and Demographic Characteristics of Children with Drug Poisoning” Anatolian Journal of Clinical Investigations 2015;9(4):189-19317. Kandolot M, Akyıldız B, Görözen F, Kutoğlu S, Patıroğlu S. “Evaluation of the poisoning cases who applied to the Pediatrics Emergency Unit” Journal of Child Health Disease,2009;52:68-74 ISSN: 0010 – 016118. Keskinbora K, Aydınlı I, “An atypical opioid analgesic: Tramadol”, The Journal of The Turkish Society of Algology 2006;18(1):5-1919. Rosenbaum TG, Kou M.” Are one or two dangerous? Tricyclic antidepressant exposure in toddlers.” The Journal of Emergency Medicine, 2005;28(2):169–17420. Yoldaş T, Güler SK, Güneş N, Çokal BG,Yurtdaş M” A Case Report of Mortal Intoxication of Amitriptyline” Ankara Medical Journal, 2014, 14(Addition- 1): 12 – 1421. Kant S ,Liebelt E,” Recognizing Serotonin Toxicity in The Pediatric Emergency Department. “Pediatric Emergancy Care, 2012;28(8):817-21; quiz 822-4. doi: 10.1097/PEC.0b013e31826289d922. Erkekoğlu P, Giray B, Şahin G. “Toxicological evaluation of tricyclic antidepressant use in risky groups” Acta Medica (Hacettepe Medical Journal) 2008; 39:22-30. eISSN:2147-9488.23. Ayaz T, Bilir Ö, Ersunan G, Şahin OZ, Yavaşi Ö, Rakıc H. ” Evaluation of Drug Intoxications Due To Suicides” Konuralp Medical Journal 2015;7(1):53-56.24. Sargın AK, Oğuz EO, Can B , Saran Y “Morphological Alerations of Methotrexate in Mouse Kidney”Anadolu University Journal of Science and Technology, 2009;10(1):197-203. http://hdl.handle.net/11421/1678

A Retrospective Analysis of Childhood Poisoning

Year 2019, Volume 41, Issue 2, 173 - 181, 01.04.2019
https://doi.org/10.20515/otd.392617

Abstract

Childhood poisonings are among the major causes of the admission to emergency units. In this study, we aimed retrospectively to determine the epidemiological and clinical characteristics of childhood poisoning among our patients. This study consisted of 1168 cases who admitted to pediatric emergency unit of our institution due to poisoning between 01/01/2011 and 14/06/2015. Poisonings were common at 13 - 48 months (44.18%). The most common poisoning agent was drugs with 545 cases (47.9%),while the second common factor was  carbon monoxide poisoning with 283 cases (24.9%). Analgesic / antipyretic agents and muscle relaxants were common agents that leads to drug poisonings(127cases, 21.67%); getting multi drugs(20.3%) and mood stabilizers followed them. Among mood stabilizers, tricyclic antidepressants were the most causes of drug poisonings. 792 cases(67.8%)  exposed to poisoning agent by digestion  (67.8%) and 301cases (25.7%) by inhalation. Drugs appeared to be primer poisoning agents in our study.  Unlike the previous studies in Turkey; poisoning by opioid analgesics and anti-neoplastic agents were also found. Although childhood poisonings are often circumvented without sequelae, they are stil major causes of admission to emergency units. 

References

  • Uziel Y, Adler A, Aharonowitz G, Franco S, Fainmesser P, Wolach B.” Un Intentional Childhood Poisoning in the Sharon Area in Israel.” Pediatric Emergency Care 2005;21(4):248-2512. Kavalcı C, Demir A, Arslan ED, Yilmaz F, Durdu T, Yel C, Gülsüm et all.”Adult Poisoning Cases in Ankara: Capital City of Turkey” International Journal of Clinical Medicine 2012;3-7A,Article ID:26339 DOI:10.4236/ijcm.2012.37A129 3. J. Kristinsson, R. Palsson, G. A. Gudjonsdottır, M. Blondal, S. Gudmundsson and C. P. Snook, “Acute Poisonings in Iceland: A Prospective Nationwide Study,” Clinical Toxicology, Vol. 46, No. 2, 2008, pp. 126-132. doi:10.1080/155636507014382684. Uludağ Ö, Tutak A, Doğukan M, Kaya R, Tutak AŞ, Çelik M “Characteristics of poisoningcases in Adiyaman City” Dicle Medical Journal 2015;42(3)284-2885. Akbay-Öntürk Y, Uçar B.”Retrospective Analysis of Childhood Poisoning at Eskişehir Region “ Journal of Child Health Disease 2003; 46:103-13. ISSN: 0010 - 01616. Kırel B, Unluoglu I, Dogruel N, Koçak K, “Retrospective Analysis of Childhood Poisoning at Eskişehir Region” Turkiye Klinikleri J Med Sci 2000;9:158-163. ISSN: 1300-0292 7. Şahin S, Carman KB, Dinleyici EC, “AcutePoisoning in children; Data of a Pediatric Emergency Unit”, Iran J Ped. Dec 2011;21(4);479-484.8. Mintegi S, Fernandez A, Alustiza J, Canduela V, Mongil I, Caubet I et all .” Emergency Visits for Childhood Poisoning: A 2 Year Prospective Multicenter Survey in Spain.” Pediatric Emergency Care 2006;22(5):334-8.9. Burillo- Putze G, Munne P, Duenas A, et al. “National Multicentre Study of Accute İntoxication İn Emergency Departments of Spain.” European Journal of Emergency Medicine 2003;10(2):101-4. 10. Dereci S, Koca T, Gençer A, Serdaroğlu F, Akçam M. “ Evaluation of Childhood Poisoning in Isparta Region “Dicle Medical Journal / 2015; 42 (3): 319-325doi: 10.5798/diclemedj.0921.2015.03.058211. Kelebek F , Satar S , Kozacı N , Açıkalın A , Gülen M , Acehan S “Emergency Medicine Admissions of Pediatric Intoxicated Cases” The Journal of Academic Emergency Medicine “2014; 13: 67-7012. Eldridge DL, Eyk JV, Kornegay C. “Pediatric Toxicology” Emergency Medicine Clin North Am 2007;15:283-30813. Demirgan EB, Erol M, Demirgan S, Yiğit Ö, Türkay M. Retrospective Evaluation of Drug Poisoning Cases Referring to Pediatric Emergency Policlinic”, The Medical Journal of Okmeydanı Training and Resarch Hospital 30(3):128-134, 2014 doi:10.5222/otd.2014.12814. Litovitz TL, Klein-Schwartz W, White S, Cobaugh DJ, Youniss.”1999 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System.” Am. J. Emerg. Med. 2000;18(5):517–574.15. Özdemir R, Bayrakci B, O Tekşam, Yalçın B, Kale G ” Thirty-threeyear experience on childhood poisoning. “The Turkish Journal of Pediatrics, 2012;54:251-259.16. Yakar B “The Familial Factors and Demographic Characteristics of Children with Drug Poisoning” Anatolian Journal of Clinical Investigations 2015;9(4):189-19317. Kandolot M, Akyıldız B, Görözen F, Kutoğlu S, Patıroğlu S. “Evaluation of the poisoning cases who applied to the Pediatrics Emergency Unit” Journal of Child Health Disease,2009;52:68-74 ISSN: 0010 – 016118. Keskinbora K, Aydınlı I, “An atypical opioid analgesic: Tramadol”, The Journal of The Turkish Society of Algology 2006;18(1):5-1919. Rosenbaum TG, Kou M.” Are one or two dangerous? Tricyclic antidepressant exposure in toddlers.” The Journal of Emergency Medicine, 2005;28(2):169–17420. Yoldaş T, Güler SK, Güneş N, Çokal BG,Yurtdaş M” A Case Report of Mortal Intoxication of Amitriptyline” Ankara Medical Journal, 2014, 14(Addition- 1): 12 – 1421. Kant S ,Liebelt E,” Recognizing Serotonin Toxicity in The Pediatric Emergency Department. “Pediatric Emergancy Care, 2012;28(8):817-21; quiz 822-4. doi: 10.1097/PEC.0b013e31826289d922. Erkekoğlu P, Giray B, Şahin G. “Toxicological evaluation of tricyclic antidepressant use in risky groups” Acta Medica (Hacettepe Medical Journal) 2008; 39:22-30. eISSN:2147-9488.23. Ayaz T, Bilir Ö, Ersunan G, Şahin OZ, Yavaşi Ö, Rakıc H. ” Evaluation of Drug Intoxications Due To Suicides” Konuralp Medical Journal 2015;7(1):53-56.24. Sargın AK, Oğuz EO, Can B , Saran Y “Morphological Alerations of Methotrexate in Mouse Kidney”Anadolu University Journal of Science and Technology, 2009;10(1):197-203. http://hdl.handle.net/11421/1678

Details

Primary Language English
Subjects Health Care Sciences and Services
Journal Section ORİJİNAL MAKALE
Authors

Burcu KÖKOĞLU (Primary Author)
Eskişehir Hoşnudiye Aile Sağlığı Merkezi
0000-0003-2108-594X
Türkiye


İlhami ÜNLÜOĞLU
ESKİŞEHİR OSMANGAZİ ÜNİVERSİTESİ TIP FAKÜLTESİ SAĞLIK UYGULAMA VE ARAŞTIRMA HASTANESİ
0000-0001-8130-1443
Türkiye


Uğur BİLGE


Sabiha ŞAHİN
0000-0003-0759-4158

Publication Date April 1, 2019
Published in Issue Year 2019, Volume 41, Issue 2

Cite

Bibtex @research article { otd392617, journal = {Osmangazi Tıp Dergisi}, issn = {1305-4953}, eissn = {2587-1579}, address = {}, publisher = {Eskişehir Osmangazi University}, year = {2019}, volume = {41}, pages = {173 - 181}, doi = {10.20515/otd.392617}, title = {A Retrospective Analysis of Childhood Poisoning}, key = {cite}, author = {Kökoğlu, Burcu and Ünlüoğlu, İlhami and Bilge, Uğur and Şahin, Sabiha} }
APA Kökoğlu, B. , Ünlüoğlu, İ. , Bilge, U. & Şahin, S. (2019). A Retrospective Analysis of Childhood Poisoning . Osmangazi Tıp Dergisi , 41 (2) , 173-181 . DOI: 10.20515/otd.392617
MLA Kökoğlu, B. , Ünlüoğlu, İ. , Bilge, U. , Şahin, S. "A Retrospective Analysis of Childhood Poisoning" . Osmangazi Tıp Dergisi 41 (2019 ): 173-181 <https://dergipark.org.tr/en/pub/otd/issue/44183/392617>
Chicago Kökoğlu, B. , Ünlüoğlu, İ. , Bilge, U. , Şahin, S. "A Retrospective Analysis of Childhood Poisoning". Osmangazi Tıp Dergisi 41 (2019 ): 173-181
RIS TY - JOUR T1 - A Retrospective Analysis of Childhood Poisoning AU - Burcu Kökoğlu , İlhami Ünlüoğlu , Uğur Bilge , Sabiha Şahin Y1 - 2019 PY - 2019 N1 - doi: 10.20515/otd.392617 DO - 10.20515/otd.392617 T2 - Osmangazi Tıp Dergisi JF - Journal JO - JOR SP - 173 EP - 181 VL - 41 IS - 2 SN - 1305-4953-2587-1579 M3 - doi: 10.20515/otd.392617 UR - https://doi.org/10.20515/otd.392617 Y2 - 2018 ER -
EndNote %0 Osmangazi Journal of Medicine A Retrospective Analysis of Childhood Poisoning %A Burcu Kökoğlu , İlhami Ünlüoğlu , Uğur Bilge , Sabiha Şahin %T A Retrospective Analysis of Childhood Poisoning %D 2019 %J Osmangazi Tıp Dergisi %P 1305-4953-2587-1579 %V 41 %N 2 %R doi: 10.20515/otd.392617 %U 10.20515/otd.392617
ISNAD Kökoğlu, Burcu , Ünlüoğlu, İlhami , Bilge, Uğur , Şahin, Sabiha . "A Retrospective Analysis of Childhood Poisoning". Osmangazi Tıp Dergisi 41 / 2 (April 2019): 173-181 . https://doi.org/10.20515/otd.392617
AMA Kökoğlu B. , Ünlüoğlu İ. , Bilge U. , Şahin S. A Retrospective Analysis of Childhood Poisoning. Osmangazi Tıp Dergisi. 2019; 41(2): 173-181.
Vancouver Kökoğlu B. , Ünlüoğlu İ. , Bilge U. , Şahin S. A Retrospective Analysis of Childhood Poisoning. Osmangazi Tıp Dergisi. 2019; 41(2): 173-181.
IEEE B. Kökoğlu , İ. Ünlüoğlu , U. Bilge and S. Şahin , "A Retrospective Analysis of Childhood Poisoning", Osmangazi Tıp Dergisi, vol. 41, no. 2, pp. 173-181, Apr. 2019, doi:10.20515/otd.392617

13299         13287  13308       13306       13305    13307  13301