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Pelvic Lymphomas in the Differential Diagnosis of Gynecological Diseases: 10 Years of Experience of the Tertiary Center.

Year 2022, Volume: 44 Issue: 6, 793 - 798, 28.11.2022
https://doi.org/10.20515/otd.1098653

Abstract

It was aimed to raise awareness about pelvic lymphoma among gynecologists by evaluating and sharing the clinical features of 12 patients diagnosed with pelvic lymphoma in the obstetrics and gynecology clinic of Eskisehir Osmangazi university.The clinicopathological data of 12 patients who were presented to our clinics with gynecological complaints and diagnosed with lymphoma between 2010 and 2020 were analyzed retrospectively from their files.In our study, extranodal primary pelvic lymphoma was detected in ten patients, while nodal lymphoma was diagnosed in two patients. The most common histological lymphoma type detected in patients was diffuse large B-cell lymphoma seen in ten patients (83.3%). It was the cervical involvement that was most commonly observed in four patients (33.3%) with primary pelvic lymphoma. Total abdominal hysterectomy was performed as a gynecological surgical procedure in two patients, while a staging surgical procedure was performed in addition to total abdominal hysterectomy in five patients. Frozen pathology method was used in only four of the patients who underwent surgical procedure. While the diagnosis of lymphoma was made by minimally invasive tissue biopsy in five patients (41.6%), it could be made after surgery in seven patients (58.3%).Keeping pelvic lymphomas in mind in the differential diagnosis of patients who are evaluated with non-specific gynecological complaints and a preliminary diagnosis of pelvic mass may prevent some unnecessary extensive oncological surgeries. Increasing awareness of pelvic lymphoma among gynecologists can help prevent delays in diagnosis and treatment

References

  • 1. Armitage JO, Weisenburger DD. New approach to classifying Non-Hodgkin's lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin's lymphoma classification project. J. Clin. Oncol. 1998 Aug;16(8):2780–2795. 2. Laurent C, Do C, Gourraud PA, et al. Prevalence of common Non-Hodgkin lymphomas and subtypes of Hodgkin lymphoma by nodal site of involvement: a systematic retrospective review of 938 cases. Medicine (Baltimore) 2015; 94:e987

Jinekolojik Hastalıkların Ayırıcı Tanısında Pelvik Lenfomalar: Üçüncü Basamak Merkezin 10 Yıllık Deneyimi.

Year 2022, Volume: 44 Issue: 6, 793 - 798, 28.11.2022
https://doi.org/10.20515/otd.1098653

Abstract

Üniversitemiz kadın doğum polikliniğinde pelvik lenfoma tanısı konulan 12 hastanın klinik özelliklerinin değerlendirilip paylaşılarak jinekologlar arasında pelvik lenfoma konusunda farkındalık yaratılması amaçlanmıştır.2010-2020 yılları arasında jinekolojik şikayetlerle Eskişehir Osmangazi Üniversitesi kadın doğum bölümüne başvuran ve lenfoma tanısı alan 12 hastanın klinikopatolojik verileri dosyalarından retrospektif olarak incelendi.Çalışmamızda 10 hastada ekstranodal primer pelvik lenfoma saptanırken, iki hastada nodal lenfoma tanısı konuldu. Hastalarda en sık saptanan histolojik lenfoma tipi, on hastada (%83.3) görülen diffüz büyük B hücreli lenfoma idi. Primer pelvik lenfomalı dört hastada (%33.3) en sık görülen servikal tutulumdu. İki hastaya jinekolojik cerrahi olarak total abdominal histerektomi, beş hastaya total abdominal histerektomiye ek olarak evreleme cerrahisi uygulandı. Cerrahi işlem uygulanan hastaların sadece dördünde frozen patoloji yöntemi kullanıldı. Lenfoma tanısı beş hastada (%41.6) minimal invaziv doku biyopsisi ile konulurken, yedi hastada (%58.3) cerrahi sonrası konulabildi.Non-spesifik jinekolojik şikayetleri olup pelvik kitle ön tanısı alan hastaların ayırıcı tanısında pelvik lenfomaların akılda tutulması gereksiz yere yapılacak onkolojik ameliyatların önüne geçebilir. Jinekologlar arasında pelvik lenfoma farkındalığının artması, tanı ve tedavide gecikmelerin önlenmesine yardımcı olabilir.

References

  • 1. Armitage JO, Weisenburger DD. New approach to classifying Non-Hodgkin's lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin's lymphoma classification project. J. Clin. Oncol. 1998 Aug;16(8):2780–2795. 2. Laurent C, Do C, Gourraud PA, et al. Prevalence of common Non-Hodgkin lymphomas and subtypes of Hodgkin lymphoma by nodal site of involvement: a systematic retrospective review of 938 cases. Medicine (Baltimore) 2015; 94:e987
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Details

Primary Language English
Subjects Health Care Administration
Journal Section ORİJİNAL MAKALE
Authors

Yusuf Çakmak 0000-0003-3128-247X

Duygu Kavak Cömert 0000-0002-9977-6567

Tufan Öge 0000-0002-1951-9713

Deniz Arık 0000-0003-0905-2731

Publication Date November 28, 2022
Published in Issue Year 2022 Volume: 44 Issue: 6

Cite

Vancouver Çakmak Y, Kavak Cömert D, Öge T, Arık D. Pelvic Lymphomas in the Differential Diagnosis of Gynecological Diseases: 10 Years of Experience of the Tertiary Center. Osmangazi Tıp Dergisi. 2022;44(6):793-8.


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