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Matür yağ doku içeren tiroid lezyonları: 7 olgu sunumu

Year 2011, Issue: 2, 100 - 104, 01.07.2011

Abstract

Tiroid bezinin matür adipoz doku ile karakterize lezyonları kapsüllü, benign bir nodül olan tirolipom ve parankimde diffüz yağ doku infi ltrasyonu olarak tanımlanan tirolipomatozistir. Bu çalışmada 4 tirolipom ve 3 tirolipomatozis olgusu sunulmuştur. Tüm olgular kadın olup yaşları 42 ile 67 arasında değişmektedir. Ortalama yaş 56’dır.Beş olgu boyunda şişlik, 1 olgu sinirlilik ve tremor, 1 olgu anemi ve hiperkalseminedeniyle başvurmuştur. Fizik muayene ile multinodüler guatr saptanan tüm olgular ultrasonografi k olarak doğrulanmış ve ince iğne aspirasyon sitolojisi uygulanmıştır. İnce iğne aspirasyon sitolojilerinin 5’i benign ve 2’si folliküler neoplazi lehine kuşkulu olarakdeğerlendirilmiştir. Altı olguya bilateral tiroidektomi uygulanmış olup, 1 olguya sağ lobektomi yapılmıştır. Cerrahi spesmenlerde multipl kolloidal nodüller izlenmiş, bunların bazılarında sarı gri alanlar tanımlanmıştır. Histolojik olarak 4 olguda yağ doku içeren nodüller mevcut olup, tirolipom tanısı almış ve 3 olgu ise tirolipomatozis olarakbilinen parankim içine saçılmış şekilde adipositler sergilemektedir. Ek olarak, 1 olguda yağ doku alanları içeren papiller karsinom ve 1 olguda papiller mikrokarsinom izlenmiştir. Cerrahi tedavi sonrası olgularda rekürrens görülmemiştir ve 1 olguya radyoaktif iyot tedavisi uygulanmıştır. Bu lezyonların farkında olmak özellikle frozenkesitlerde ve sitoloji materyallerinde patologları yanlış tanıdan korumak açısından oldukça önemlidir.

Thyroid lesions containing mature adipose tissue: 7 case reports

Year 2011, Issue: 2, 100 - 104, 01.07.2011

Abstract

Lesions characterized by mature adipose tissue in thyroid gland are thyrolipoma, described as a capsulated benign nodule and thyrolipomatosis, diffuse infi ltration of adipose tissue in parenchyma. Here, we present 4 thyrolipoma and 3 thyrolipomatosis cases. All cases were female with ages from 42 to 67. The median age was56 years. Five cases presented neck mass, 1 with angerness and tremor and 1 with anemia and hypercalsemia. All cases revealed multinodular goiter in physical examination confi rmed ultrasonographically and went on fi ne needle aspiration (FNA) biopsy. Five of the FNA biopsies were diagnosed as benign and 2 cases as suspected forfollicular neoplasm. Six cases operated bilaterally whereas 1 case had right lobectomy. The surgical specimens showed multiple colloidal nodules, some of which were described as implying yellow gray areas. Histologically, 4 cases had nodules with fat tissue, diagnosed as thyrolipoma. Three cases demonstrated scattered adipocytesin parenchyma known as thyrolipomatosis. Additionally, in one case fat tissue containing papillary carcinoma and in another case papillary microcarcinoma were observed. The patients had no recurrence after surgery and one case we went onradioactive iodine therapy. It is important to be aware of these lesions for preventing pathologists from misdiagnosis especially in frozen sections and cytologic materials.

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Details

Other ID JA42TC23TR
Journal Section Case Report
Authors

Yelda Dere This is me

Ayşegül Aksoy Altınboğa This is me

Ayşegül Sarı This is me

Canan Sadullahoğlu This is me

Kemal Atahan This is me

Publication Date July 1, 2011
Submission Date July 1, 2011
Published in Issue Year 2011 Issue: 2

Cite

APA Dere, Y., Altınboğa, A. A., Sarı, A., Sadullahoğlu, C., et al. (2011). Thyroid lesions containing mature adipose tissue: 7 case reports. Pamukkale Medical Journal(2), 100-104.
AMA Dere Y, Altınboğa AA, Sarı A, Sadullahoğlu C, Atahan K. Thyroid lesions containing mature adipose tissue: 7 case reports. Pam Med J. July 2011;(2):100-104.
Chicago Dere, Yelda, Ayşegül Aksoy Altınboğa, Ayşegül Sarı, Canan Sadullahoğlu, and Kemal Atahan. “Thyroid Lesions Containing Mature Adipose Tissue: 7 Case Reports”. Pamukkale Medical Journal, no. 2 (July 2011): 100-104.
EndNote Dere Y, Altınboğa AA, Sarı A, Sadullahoğlu C, Atahan K (July 1, 2011) Thyroid lesions containing mature adipose tissue: 7 case reports. Pamukkale Medical Journal 2 100–104.
IEEE Y. Dere, A. A. Altınboğa, A. Sarı, C. Sadullahoğlu, and K. Atahan, “Thyroid lesions containing mature adipose tissue: 7 case reports”, Pam Med J, no. 2, pp. 100–104, July 2011.
ISNAD Dere, Yelda et al. “Thyroid Lesions Containing Mature Adipose Tissue: 7 Case Reports”. Pamukkale Medical Journal 2 (July 2011), 100-104.
JAMA Dere Y, Altınboğa AA, Sarı A, Sadullahoğlu C, Atahan K. Thyroid lesions containing mature adipose tissue: 7 case reports. Pam Med J. 2011;:100–104.
MLA Dere, Yelda et al. “Thyroid Lesions Containing Mature Adipose Tissue: 7 Case Reports”. Pamukkale Medical Journal, no. 2, 2011, pp. 100-4.
Vancouver Dere Y, Altınboğa AA, Sarı A, Sadullahoğlu C, Atahan K. Thyroid lesions containing mature adipose tissue: 7 case reports. Pam Med J. 2011(2):100-4.

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