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            <front>

                <journal-meta>
                                                                <journal-id>pediatr pract res</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Pediatric Practice and Research</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">2147-6470</issn>
                                                                                                        <publisher>
                    <publisher-name>Resul YILMAZ</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.21765/pprjournal.1008354</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Health Care Administration</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Sağlık Kurumları Yönetimi</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Ultrasonographic Measurement of the Thyroid Isthmus Thickness in Healthy Turkish Infants, Children, and Adolescents</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="tr">
                                    <trans-title>Sağlıklı Türk İnfant, Çocukluk ve Adolesan Yaş Grubunda Tiroid İstmus Kalınlığının Ultrasonografik Ölçümü</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-5191-0491</contrib-id>
                                                                <name>
                                    <surname>Çolak</surname>
                                    <given-names>Edis</given-names>
                                </name>
                                                                    <aff>UNIVERSITY OF HEALTH SCIENCES, İZMİR DR. BEHÇET UZ HEALTH RESEARCH CENTER FOR PEDIATRIC DISEASES AND SURGERY, DEPARTMENT OF INTERNAL MEDICINE, RADIOLOGY SCIENCE MAJOR</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-9153-8409</contrib-id>
                                                                <name>
                                    <surname>Özkan</surname>
                                    <given-names>Behzat</given-names>
                                </name>
                                                                    <aff>UNIVERSITY OF HEALTH SCIENCES, İZMİR DR. BEHÇET UZ HEALTH RESEARCH CENTER FOR PEDIATRIC DISEASES AND SURGERY, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, ENDOCRINOLOGY AND METABOLIC DISEASES</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-7265-8862</contrib-id>
                                                                <name>
                                    <surname>Polat</surname>
                                    <given-names>Burak</given-names>
                                </name>
                                                                    <aff>UNIVERSITY OF HEALTH SCIENCES, İZMİR DR. BEHÇET UZ HEALTH RESEARCH CENTER FOR PEDIATRIC DISEASES AND SURGERY, DEPARTMENT OF INTERNAL MEDICINE, RADIOLOGY SCIENCE MAJOR</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-2634-7515</contrib-id>
                                                                <name>
                                    <surname>Genç</surname>
                                    <given-names>Sinan</given-names>
                                </name>
                                                                    <aff>UNIVERSITY OF HEALTH SCIENCES, İZMİR DR. BEHÇET UZ HEALTH RESEARCH CENTER FOR PEDIATRIC DISEASES AND SURGERY, DEPARTMENT OF INTERNAL MEDICINE, RADIOLOGY SCIENCE MAJOR, PEDIATRIC RADIOLOGY</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20211231">
                    <day>12</day>
                    <month>31</month>
                    <year>2021</year>
                </pub-date>
                                        <volume>9</volume>
                                        <issue>3</issue>
                                        <fpage>126</fpage>
                                        <lpage>129</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20211011">
                        <day>10</day>
                        <month>11</month>
                        <year>2021</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20211120">
                        <day>11</day>
                        <month>20</month>
                        <year>2021</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2013, Pediatric Practice and Research</copyright-statement>
                    <copyright-year>2013</copyright-year>
                    <copyright-holder>Pediatric Practice and Research</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Aim: The importance of establishing reference ranges for thyroid volume is a worldwide trend, however, to date, limited data are available regarding thyroid isthmus thickness (TIT) in healthy children. The present study aimed to report the reference values for TIT in children aged between 0 and 18 years from Turkey.Material and Method: The TIT was measured by ultrasonography in 447 subjects between December 2018 and September 2020. The 3rd, 10th, 25th, 50th, 75th, and 95th percentiles of the TIT according to age and gender were determined and compared with published data. The TIT values were compared with children’s age, gender, and Z-score data for weight, height, and body mass index (BMI).Results: The median [interquartile range (IQR) 25 - 75] values for TIT were 1.5 (1.3-2.0) mm. The TI was thicker in females than in males and this gender difference was statistically significant (1.6mm vs. 1.5mm, p=0.023, respectively). The TIT was highly significantly associated with age, and Z-scores for weight, height, and BMI (r=0.461, r=0.457, r=0.448, and r=0.434, respectively; p</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="tr">
                            <p>Amaç: Tiroid bez hacmi için referans aralıklarının oluşturulması dünya çapında bir trend olmasına rağmen bugüne kadar sağlıklı çocuklarda tiroid istmus kalınlığı (TİK) ile ilgili sınırlı veri mevcuttur. Bu çalışmanın amacı 0-18 yaş arası Türk çocuklarda TİK&#039;nın referans değerlerini belirlemektir.Gereç ve Yöntem: Aralık 2018 - Eylül 2020 tarihleri arasında 447 kişide TİK ultrasonografi ile ölçüldü. TİK için 3., 10., 25., 50., 75. ve 95. persentil değerleri yaş ve cinsiyete göre hesaplandı ve yayınlanan verilerle karşılaştırıldı. TİK değerleri, çocukların yaş, cinsiyet ve ağırlık, boy, vücut kitle indeksi (VKİ) Z-skorları ile karşılaştırıldı.Bulgular: TİK medyan [çeyrekler arası aralık (IQR) 25 - 75] değerleri 1.5 (1.3-2.0) mm idi. Tiroid istmus kadınlarda erkeklere göre daha kalındı ve bu cinsiyet farkı istatistiksel açıdan anlamlıydı (sırasıyla 1.6mm, 1.5mm ve p=0.023). TİK ve yaş, ağırlık, boy, VKİ Z-skor değerleri arasında belirgin fark gözlendi (sırasıyla r=0.461, r=0.457, r=0.448 ve r=0.434; p</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Thyroid isthmus</kwd>
                                                    <kwd>  thyroid isthmus thickness</kwd>
                                                    <kwd>  ultrasound</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="tr">
                                                    <kwd>Tiroid istmus</kwd>
                                                    <kwd>  tiroid istmus kalınlığı</kwd>
                                                    <kwd>  ultrason</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
    <back>
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    </article>
