Research Article
PDF EndNote BibTex RIS Cite

Çocukluk döneminde labial füzyona yaklaşımımız: Tek merkezde sekiz yıllık deneyim.

Year 2022, Volume 10, Issue 3, 118 - 122, 31.12.2022
https://doi.org/10.21765/pprjournal.1182905

Abstract

Amaç: Bu çalışmada; hastanemiz Çocuk Cerrahisi Polikliniği’ne doğrudan başvuran ya da konsülte edilen labial füzyon hastalarının klinik bilgileri ve tedavi sonuçlarını tespit etmeyi amaçladık. Gereç ve Yöntem: Hastanemiz Çocuk Cerrahisi Polikliniği’ne başvuran labial füzyonlu puberte öncesi yaş grubunda olan kız hastalar, yaşları, şikayetleri, önerilen tedavi şekli, tekrarlama süre ve oranları, oluşan komplikasyonlar açısından geriye dönük olarak hastanemiz veritabanı kullanılarak gözden geçirildi. Bulgular: Bu çalışmaya, hastanemizde yaşları 32 gün ile 10 yıl arasında olan labial füzyonlu 438 olgu dahil edildi. Hastaların 359(%82)’ unda labial füzyon, sadece labia minörlerde tama yakın bir açıklık ve 180(%41)’ inde labial füzyona bağlı ek sorunlar tespit edildi. Hastalar topikal östrojen ve Centella Asiatica bitkisinin hammaddesini içeren kremler ve manuel füzyon ayrılmasıyla tedavi edildi. Bu hastaların 18(4%)’ inde labial füzyonda tekrarlama görüldü. Tespit esnasındaki hasta yaşının büyük ve labial füzyona bağlı ek sorunların hastalığın tekrarı üzerinde etkili olduğu bulundu. Sonuç: Labial füzyonun tekrarlama oranını, yaşın büyük olması ve ek problemler arttırabilmektedir. Patolojinin erken saptanıp, gerekli önlemler uygulanması ve tedaviye topikal östrojenli yanısıra Centella Asiatica bitkisinin hammaddesini içeren kremlerin gerekirse kombine olarak kullanılmasıyla da daha hızlı, yüzgüldüren ve tekrarlama riskinin daha az olduğu sonuçlar alabileceğimizi düşünmekteyiz.

References

  • References: 1. Şahin AH, Yılmaz Ms. Retrospective evaluation of labial fusion in girls. J Health Sci Med 2022; 5(3): 746-749.
  • 2. Singh P, Han HC. Labial adhesions in postmenopausal women: presentation and management. Int Urogynecol J. 2019;30(9):1429-1432.
  • 3. Bacon JL, Romano ME, Quint EH. Clinical Recommendation: Labial Adhesions. J Pediatr Adolesc Gynecol. 2015;28(5):405-9.
  • 4. Cağlar MK. Serum estradiol levels in infants with and without labial adhesions: the role of estrogen in the etiology and treatment. Pediatr Dermatol. 2007;24 (4):373-5.
  • 5. Vilano SE, Robbins CL. Common prepubertal vulvar conditions. Curr Opin Obstetr Gynecol 2016; 28: 359-365
  • 6. Saberi N, Gholipour F. Extensive Labial Adhesion Causing Voiding Urinary Symptoms in a Postmenopausal Woman: A Case Report. Iran J Med Sci. 2020;45 (1):73-75.
  • 7. Schober J, Dulabon L, Martin-Alguacil N, Kow LM, Pfaff D. Significance of topical estrogens to labial fusion and vaginal introital integrity. J Pediatr Adolesc Gynecol. 2006;19 (5):337-9.
  • 8. Öztorun Cİ, Erten EE, Bostancı SA, et. ,al. Approach to Labial Fusion in Children: 16 Years of Experience. Pediatr Pract Res 2022;10(1): 6-10.
  • 9. Morin JP, Tew CE, Puntney HL, Roser ML, Saltzman AF. Recurrence rates after surgical management of labial adhesions. J Pediatr Urol. 2021;17(5):705.e1-705.e5.
  • 10. Wejde E, Ekmark AN, Stenström P. Treatment with estrogen or manual separation for labial adhesions - initial outcome and long-term follow-up. BMC Pediatr. 2018; 18 (1):104.
  • 11. Mahato GN, Palit PR, Hasanuzzaman MD. To compare the outcome of estrogen and betamethasone cream in the treatment of labial adhesion in pre-pubertal girls. Bangladesh J Child Health. 2019; 43 (3):161-164.
  • 12. Eroğlu E, Yip M, Oktar T, Kayiran SM, Mocan H. How should we treat prepubertal labial adhesions? Retrospective comparison of topical treatments: estrogen only, betamethasone only, and combination estrogen and betamethasone. J Pediatr Adolesc Gynecol. 2011;24 (6):389-91.
  • 13. Saraç F, Büyükbeşe SS, Toptaş M, Saygılı A, Şahin K. Labial Füzyonda Tedavi Yaklaşımlarımız. Med Bull Haseki. 2016;54:67-69.
  • 14. Singkhorn S, Tantisira MH, Tanasawet S, Hutamekalin P, Wongtawatchai T, and Sukketsiri W. Induction of keratinocyte migration by ECa 233 is mediated through FAK/Akt, ERK, and p38 MAPK signaling. Phytother. Res. 2018; 32 (7):1397-1403.

Our approach to labial fusion during childhood: Eight years of experience in a single center.

Year 2022, Volume 10, Issue 3, 118 - 122, 31.12.2022
https://doi.org/10.21765/pprjournal.1182905

Abstract

Aim: In this study; we aimed to determine the clinical information and treatment results of labial fusion patients who applied directly to or consulted the Pediatric Surgery Outpatient Clinic of our hospital. Material and Method: Female patients in the prepubertal age group with labial fusion who applied to the Pediatric Surgery Outpatient Clinic of our hospital were retrospectively reviewed in terms of age, complaints, recommended treatment, recurrence rates, time to recurrence, and complications. Results: This study involved 438 patients with labial fusion aged between 32 days and 10 years in our hospital. Labial fusion was detected in 359 (82%) of the patients, a nearly complete opening only in the labia minora, and additional problems related to labial fusion in 180 (41%) patients. The patients were treated with topical estrogen and creams containing the raw material of the Centella Asiatica plant and manual fusion separation. Recurrence of labial fusion was seen in 18(4%) of these patients. It was found that the patient's age at the time of detection and additional problems related to labial fusion were effective on the recurrence of the disease. Conclusion: Older age and additional problems may increase the recurrence rate of labial fusion. We think that we can get results faster, with less risk of recurrence, by detecting the pathology early, applying the necessary precautions, and using the creams containing the raw material of Centella Asiatica as well as the raw material of the Centella Asiatica plant in combination, if necessary.

References

  • References: 1. Şahin AH, Yılmaz Ms. Retrospective evaluation of labial fusion in girls. J Health Sci Med 2022; 5(3): 746-749.
  • 2. Singh P, Han HC. Labial adhesions in postmenopausal women: presentation and management. Int Urogynecol J. 2019;30(9):1429-1432.
  • 3. Bacon JL, Romano ME, Quint EH. Clinical Recommendation: Labial Adhesions. J Pediatr Adolesc Gynecol. 2015;28(5):405-9.
  • 4. Cağlar MK. Serum estradiol levels in infants with and without labial adhesions: the role of estrogen in the etiology and treatment. Pediatr Dermatol. 2007;24 (4):373-5.
  • 5. Vilano SE, Robbins CL. Common prepubertal vulvar conditions. Curr Opin Obstetr Gynecol 2016; 28: 359-365
  • 6. Saberi N, Gholipour F. Extensive Labial Adhesion Causing Voiding Urinary Symptoms in a Postmenopausal Woman: A Case Report. Iran J Med Sci. 2020;45 (1):73-75.
  • 7. Schober J, Dulabon L, Martin-Alguacil N, Kow LM, Pfaff D. Significance of topical estrogens to labial fusion and vaginal introital integrity. J Pediatr Adolesc Gynecol. 2006;19 (5):337-9.
  • 8. Öztorun Cİ, Erten EE, Bostancı SA, et. ,al. Approach to Labial Fusion in Children: 16 Years of Experience. Pediatr Pract Res 2022;10(1): 6-10.
  • 9. Morin JP, Tew CE, Puntney HL, Roser ML, Saltzman AF. Recurrence rates after surgical management of labial adhesions. J Pediatr Urol. 2021;17(5):705.e1-705.e5.
  • 10. Wejde E, Ekmark AN, Stenström P. Treatment with estrogen or manual separation for labial adhesions - initial outcome and long-term follow-up. BMC Pediatr. 2018; 18 (1):104.
  • 11. Mahato GN, Palit PR, Hasanuzzaman MD. To compare the outcome of estrogen and betamethasone cream in the treatment of labial adhesion in pre-pubertal girls. Bangladesh J Child Health. 2019; 43 (3):161-164.
  • 12. Eroğlu E, Yip M, Oktar T, Kayiran SM, Mocan H. How should we treat prepubertal labial adhesions? Retrospective comparison of topical treatments: estrogen only, betamethasone only, and combination estrogen and betamethasone. J Pediatr Adolesc Gynecol. 2011;24 (6):389-91.
  • 13. Saraç F, Büyükbeşe SS, Toptaş M, Saygılı A, Şahin K. Labial Füzyonda Tedavi Yaklaşımlarımız. Med Bull Haseki. 2016;54:67-69.
  • 14. Singkhorn S, Tantisira MH, Tanasawet S, Hutamekalin P, Wongtawatchai T, and Sukketsiri W. Induction of keratinocyte migration by ECa 233 is mediated through FAK/Akt, ERK, and p38 MAPK signaling. Phytother. Res. 2018; 32 (7):1397-1403.

Details

Primary Language English
Subjects Health Care Sciences and Services
Journal Section Original Articles
Authors

Mehmet UYSAL> (Primary Author)
KARAMANOGLU MEHMETBEY UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF PEDIATRIC SURGERY
0000-0003-1561-6601
Türkiye

Early Pub Date September 4, 2022
Publication Date December 31, 2022
Acceptance Date December 30, 2022
Published in Issue Year 2022, Volume 10, Issue 3

Cite

Vancouver Uysal M. Our approach to labial fusion during childhood: Eight years of experience in a single center.. Pediatric Practice and Research. 2022; 10(3): 118-122.