Case Report
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Çocuklarda Nöbet ile Prezente Olan Nadir Görülen Nöraksisin Kalsifiye Psödoneoplazmı (CAPNON)

Year 2022, Volume 10, Issue 3, 131 - 133, 31.12.2022
https://doi.org/10.21765/pprjournal.1223145

Abstract

Nöraksisin kalsifiye psödoneoplazmaları (CAPNON), santral sinir sisteminin nonneoplastik ve nadir görülen lezyonlarıdır. Etiyolojisi belirsizdir ve cerrahi olarak çıkarılması genellikle küratiftir. Radyografik özellikleri, bilgisayarlı beyin tomografide belirgin kalsifikasyonlar ve manyetik rezonans (MR) görüntülemede değişken kontrastlanma gösteren, T1 ve T2 ağırlıklı görüntülerde hipointensite görülmesiyle tanımlanmıştır. Erişkinlerde de sık rastlanmayan CAPNON, çocuklarda ise çok nadir görülmektedir. Bildirilen CAPNON tümörlerinin büyük çoğunluğu intrakraniyal olmakla birlikte, spinal kord da bulunabilir. Asemptomatik olabildiği gibi semptom gösterdiğinde de baş ağrıları, nöbet ve fokal nörolojik defisitler ile presente olabilir. Literatürde çok nadir bildirilen, değişken bilincin eşlik ettiği fokal nöbet epizodları ile başvuran ve CAPNON tanısı alan opere olmadan takip edilen 12 yaşında çocuk olguyu sunuyoruz.

References

  • 1- Tatke M, Singh AK, Gupta V: Calcifying pseudoneoplasm of the CNS. Br J Neurosurg 2001; 15: 521–523,
  • 2- Lyapichev K, Bregy A, Shah AH, Shah K, Desai MB, Petito C, et.al. Occipital calcified pseudoneoplasms of the neuraxis (CAPNON): understanding a rare pathology. BMJ Case Rep. 2014 Dec 5;2014:bcr2014206855.
  • 3- Stienen MN, Abdulazim A, Gautschi OP, Schneiderhan TM, Hildebrandt G, Lücke S. Calcifying pseudoneoplasms of the neuraxis (CAPNON): clinical features and therapeutic options. Acta Neurochir (Wien). 2013; 155(1): 9-17.
  • 4- Montibeller GR, Stan AC, Krauss JK, Nakamura M. Calcifying pseudoneoplasm of the inferior colliculus: an unusual location for a rare tumor: case report. Neurosurgery. 2009; 65(5): E1005-6; discussion E1006
  • 5- Bartanusz V, Ziu M, Jimenez DF, Henry JM: Calcifying pseudoneoplasm of the atlantoaxial joint in a child. J Neurosurg Spine 2013; 18 :367–371,
  • 6- Bertoni F, Unni KK, Dahlin DC, Beabout JW, Onofrio BM: Calcifying pseudoneoplasms of the neural axis. J Neurosurg 1990; 72 :42–48
  • 7- Aiken AH, Akgun H, Tihan T, Barbaro N, Glastonbury C: Calcifying pseudoneoplasms of the neuraxis: CT, MR imaging, and histologic features. AJNR Am J Neuroradiol 2009; 30: 1256–1260,
  • 8- Safaee MM, Jonzzon S, López GY, Asaikar S, Tihan T, Glenn OA, et al. Perilesional edema associated with an intracranial calcifying pseudoneoplasm of the neuraxis in a child: case report and review of imaging features. J Neurosurg Pediatr. 2018; 22(5): 528-531.

Rare Calcified Pseudoneoplasm of Neuraxis Presenting with Seizure in Children (CAPNON)

Year 2022, Volume 10, Issue 3, 131 - 133, 31.12.2022
https://doi.org/10.21765/pprjournal.1223145

Abstract

Calcified pseudoneoplasms of neuraxis (CAPNON) are nonneoplastic and rare lesions of the central nervous system. Its etiology is unclear and its surgical removal is usually curative. Its radiographic features were defined by prominent calcifications seen on computed tomography (CT) and hypointensity on T1- and T2-weighted images with variable enhancement on magnetic resonance (MR) imaging. CANON, which is not common in adults, is very rare in children. The majority of reported CAPNON tumors are intracranial, although the spinal cord may also be found. It may be asymptomatic or present with headaches, seizures and focal neurological deficits when symptomatic. We present a case of a 12-year-old boy who presented with focal seizure episodes accompanied by variable consciousness and was diagnosed as CAPNON, which was rarely reported in the literature, and was followed up without surgery.

References

  • 1- Tatke M, Singh AK, Gupta V: Calcifying pseudoneoplasm of the CNS. Br J Neurosurg 2001; 15: 521–523,
  • 2- Lyapichev K, Bregy A, Shah AH, Shah K, Desai MB, Petito C, et.al. Occipital calcified pseudoneoplasms of the neuraxis (CAPNON): understanding a rare pathology. BMJ Case Rep. 2014 Dec 5;2014:bcr2014206855.
  • 3- Stienen MN, Abdulazim A, Gautschi OP, Schneiderhan TM, Hildebrandt G, Lücke S. Calcifying pseudoneoplasms of the neuraxis (CAPNON): clinical features and therapeutic options. Acta Neurochir (Wien). 2013; 155(1): 9-17.
  • 4- Montibeller GR, Stan AC, Krauss JK, Nakamura M. Calcifying pseudoneoplasm of the inferior colliculus: an unusual location for a rare tumor: case report. Neurosurgery. 2009; 65(5): E1005-6; discussion E1006
  • 5- Bartanusz V, Ziu M, Jimenez DF, Henry JM: Calcifying pseudoneoplasm of the atlantoaxial joint in a child. J Neurosurg Spine 2013; 18 :367–371,
  • 6- Bertoni F, Unni KK, Dahlin DC, Beabout JW, Onofrio BM: Calcifying pseudoneoplasms of the neural axis. J Neurosurg 1990; 72 :42–48
  • 7- Aiken AH, Akgun H, Tihan T, Barbaro N, Glastonbury C: Calcifying pseudoneoplasms of the neuraxis: CT, MR imaging, and histologic features. AJNR Am J Neuroradiol 2009; 30: 1256–1260,
  • 8- Safaee MM, Jonzzon S, López GY, Asaikar S, Tihan T, Glenn OA, et al. Perilesional edema associated with an intracranial calcifying pseudoneoplasm of the neuraxis in a child: case report and review of imaging features. J Neurosurg Pediatr. 2018; 22(5): 528-531.

Details

Primary Language Turkish
Subjects Health Care Sciences and Services
Journal Section Case Reports
Authors

Kübra TAŞAR> (Primary Author)
NECMETTİN ERBAKAN ÜNİVERSİTESİ, MERAM TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, ÇOCUK SAĞLIĞI VE HASTALIKLARI ANABİLİM DALI
0000-0002-8965-2907
Türkiye


Abdullah CANBAL>
NECMETTIN ERBAKAN UNIVERSITY, MERAM SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF CHILD HEALTH AND DISEASES, NEUROLOGY
0000-0002-4048-1000
Türkiye


Burcu ÇALIŞKAN>
NECMETTIN ERBAKAN UNIVERSITY, MERAM SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF CHILD HEALTH AND DISEASES, NEUROLOGY
0000-0001-8022-8862
Türkiye


Saliha YAVUZ ERAVCI This is me
NECMETTİN ERBAKAN ÜNİVERSİTESİ, MERAM TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, ÇOCUK SAĞLIĞI VE HASTALIKLARI ANABİLİM DALI, NÖROLOJİ BİLİM DALI
0000-0002-5277-5583
Türkiye


Cengiz KADIYORAN>
NECMETTIN ERBAKAN UNIVERSITY, MERAM SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, RADIOLOGY SCIENCE MAJOR
0000-0002-7173-3530
Türkiye


Mehmet Fatih ERDİ>
NECMETTİN ERBAKAN ÜNİVERSİTESİ, MERAM TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, BEYİN VE SİNİR CERRAHİSİ ANABİLİM DALI
0000-0003-3621-6658
Türkiye


Ahmet GÜVEN>
NECMETTİN ERBAKAN ÜNİVERSİTESİ, MERAM TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, ÇOCUK SAĞLIĞI VE HASTALIKLARI ANABİLİM DALI, NÖROLOJİ BİLİM DALI
0000-0002-6085-1582
Türkiye

Early Pub Date September 4, 2022
Publication Date December 31, 2022
Acceptance Date December 30, 2022
Published in Issue Year 2022, Volume 10, Issue 3

Cite

Vancouver Taşar K. , Canbal A. , Çalışkan B. , Yavuz Eravcı S. , Kadıyoran C. , Erdi M. F. , Güven A. Çocuklarda Nöbet ile Prezente Olan Nadir Görülen Nöraksisin Kalsifiye Psödoneoplazmı (CAPNON). Pediatric Practice and Research. 2022; 10(3): 131-133.