Recent Advances in 4D Bioprinting

Year 2020, Volume: 1 Issue: 1, 20 - 23, 17.08.2020

Ali Akpek , Ayça Bal Öztürk , Emine Alarçin , Huseyin Avci , Meltem Avcı

Abstract

Four-dimensional (4D) bioprinting, is generally accepted as the future of
biofabrication technologies. 4D bioprinting develops dynamic and 3D based
biological materials which can shift their shapes or alter their behaviors when several
stimulants like electricity, temperature, humidity, magnetic etc. are applied. In this
review, we highlighted the important aspects of several smart materials for 4D
bioprinting that have been used recently for biofabrication researches. It is believed
that in immediate future, smart materials and 4D Bioprinting techniques will have an
excessive importance for designing of soft robotic systems and architecture of
hierarchial, compex, thick and vascularized tissue structures

Keywords

4D Bioprinting, 3D Bioprinting, biofabrication, tissue engineering, smart materials

4B Biyobaskı Çalışmalarında Güncel Yenilikler

Abstract

Dört boyutlu (4B) biyobaskı tekniklerinin biyofabrikasyon teknolojilerinin geleceği
olduğu düşünülmektedir. Elektrik, sıcaklık, nem, manyetik vs. gibi uyarıcılar aracılığı
ile şekil değiştiren akıllı malzemeler kullanılarak ortaya çıkartılmış olan 4B biyobaskı
tekniği, 3B biyolojik materyallerden oluşmuş ve zamanla şekil değiştirebilen yapılar
üretilebilmektir. Bu mini derlemede bu alanda son yıllarda ortaya konmuş olan pek
çok akıllı malzeme ve bunların önemleri açıklanmıştır. Akıllı malzemelerin ve 4B
biyoyazıcı tekniklerinin çok yakın bir gelecek içerisinde yumuşak robotik sistemlerin
tasarımlarında ve hiyerarşik, kompleks, kalın ve damar dokusu eklemlenmiş doku
yapılarının tasarımlanmasında aşırı derecede önem kazanacağı düşünülmektedir.

Keywords

4B Biyobaskı, 3B Biyobaskı, Biyofabrikasyon, Doku Mühendisliği, Akıllı Malzemeler

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