11-13+6 GEBELİK HAFTALARI ARASINDA FETAL BAZİLER ARTER DOPPLER ÖLÇÜMLERİNİN UYGULANABİLİRLİĞİ VE TEKRARLANABİLİRLİĞİ ÜZERİNE BİR ÇALIŞMA

Year 2023, , 10 - 16, 28.02.2023

Tuğba Saraç Sivrikoz , Selen Gürsoy Erzincan , Gürcan Türkyılmaz , Nihat Demirkol , Recep Has , İbrahim Kalelioğlu

https://doi.org/10.26650/JARHS2023-1202942

Abstract

Amaç: Fetal baziler arter Doppler (BA-D) ölçümleri, erken fetal anemi tahmini için ilk trimesterde orta serebral arter Doppleri’ne daha kolay bir alternatif olabilir. Amacımız, ilk trimesterde BA-D’nin fizibilitesini test etmek ve referans aralıklarını oluşturmaktır. Gereç ve Yöntem: Çalışma retrospektif olarak planlanmış olup, ilk üç ayda trans abdominal Doppler ultrasonda baş-popo mesafesi (BPM) 45 ile 81 mm arasında ölçülen 145 tekil gebelik dahil edildi. BA midsagittal düzlemde görüntülenerek, puls Doppler beyin sapının ön ekojenik hattının hemen kaudaline yerleştirilmiş ve insonasyon açısı 30°’nin altında tutulmuştur. Pulsatilite indeksi (PI) ve pik sistolik hız (PSH) ölçüldü. Bulgular: 138 fetüs kriterlere uygun idi. Ortalama BPM 60.5±10,6 mm (aralık:45-81 mm), ortalama ense saydamlığı (ES) 1.51±0.46 mm’di. PI ve PSH; gebelik yaşı, BPM, ES, biparietal çap ile değişiklik göstermiş, her değişken için regresyon modelleri oluşturulmuştur (p<0.05). Her gebelik haftasında BA PI ve PSH Doppler ölçümleri için 5.50. ve 95. persentiller belirlendi. BA PI ve PSH ölçümleri için korelasyon katsayısı sırasıyla 0.792 (%95 GA=0.661-0.876; p<0.01) ve 0.457 (%95 GA=0.208-0.650; p<0.01) idi. Sonuç: BA PI ve PSV değerleri sağlıklı fetüsler birinci trimester sonografisi sırasında belirlenmiştir. Gözlemci içi tekrarlanabilirlik BA için kabul edilebilir olup erken fetal anemi tanısında kullanılması için yeni çalışmalarla desteklenmelidir.

Keywords

Baziler arter, Doppler ultrason, ilk üçay sonografisi, piksistolik velosite, pulsatilite indeksi

Supporting Institution

Bulunmuyor

Project Number

Bulunmuyor

Thanks

Bulunmuyor

A STUDY ON THE FEASIBILITY AND REPEATABILITY OF FETAL BASILAR ARTERY DOPPLER MEASUREMENTS BETWEEN 11 AND 13+6 WEEKS OF GESTATION

Abstract

Objective: The fetal basilary artery Doppler (BA-D) measurements could be an easier alternative method to middle cerebral artery Doppler at the first trimester for the prediction of early fetal anemia. Our aim is to test its feasibility and construct reference ranges of BA-D at the first trimester Materials and Methods: The study was analyzed retrospectively by using a transabdominal Doppler ultrasound which measured the fetuses at a crown-rump length (CRL) ranging from 45 to 81mm in 145 singleton pregnancies at the first trimester. The BA was imaged in the midsagittal plane, the pulse Doppler was placed just caudal to the anterior echogenic line of the brainstem, and the insonation angle was kept below 30°. The pulsatility index (PI) and peak systolic velocity (PSV) were also measured. Results: A total of 138 out of the 145 fetuses were included. The mean CRL was 60.5±10.6 mm (range: 45-81mm). The mean nuchal translucency (NT) was 1.51±0.46 mm. The PI and PSV varied significantly, with the gestational age, CRL, NT, biparietal diameter (p < 0.05), and regression models being constructed for each variable. The 5th, 50th, and 95th percentiles for the BA PI and PSV Doppler measurements at each gestational week were determined. Intraclass correlation coefficient for the BA PI and PSV measurements were 0.792 (95% CI=0.661-0.876; p<0.01) and 0.457 (95% CI=0.208-0.650; p<0.01), respectively. Conclusion: The BA PI and PSV values were determined during the first trimester sonography of healthy fetuses. Intraobserver reproducibility is acceptable for BA and should be supported by new studies for its use in the diagnosis of early fetal anemia.

Keywords

Basilar artery, Doppler ultrasound, first trimester ultrasound, peak systolic velocity, pulsatility index

Project Number

Bulunmuyor

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