THE RELATIONSHIP OF COVID-19 MORTALITY AND PROGNOSTIC NUTRITIONAL INDEX IN GERIATRIC POPULATION

Year 2024, Volume: 9 Issue: 3, 407 - 417, 31.12.2024

Atacan Aras , Kamile Silay , Güneş Arık , Mercan Taştemur , İhsan Ateş , Rana Tuna Doğrul , Hande Selvi Öztorun , Erhan Özenç , Hilal Heybeli

https://doi.org/10.25279/sak.1163623

Abstract

Introduction: We aimed to investigate the effect of Prognostic nutritional index (PNI) on prognosis and mortality among elderly patients with COVID-19 infection. Methods: 401 patients included in the study, all of them were over 65 years old. PNI was compared with laboratory and demographic data. Results: Analysis was made of 401 patients, comprising 181 (45%) females and median age of 75.8±7.7 years. Three hundred and two (75.4%) patients were in the recovered group. Mean PNI value was 41.9±5.9 in the recovered group and 36.9±7 in the exitus group (p<0.001). According to multivariate logistic regression analysis, advanced age, high maximum ferritin level, high maximum IL-6 level and PNI<40 were identified as independent risk factors predicting exitus in COVID-19 patients.
Conclusion: Prognostic models which including PNI scoring system, have been found to be useful in assessing the progression of COVID-19 and enhancing patient monitoring. Since all the patients included in our study were in the geriatric age group, the data we obtained may guide the course of COVID-19 infection, especially in patients in this age group.

Keywords

Nutrition, Mortality, SARS-COV-2, Elderly, Geriatrics

Ethical Statement

The authors have no conflict of interest to declare. The author(s) received no financial support for the research, authorship, and/or publication of this article. Informed consent was obtained from all individual participants included in the study. All procedures performed in this study were conducted in accordance with the ethical standards of the institutional and / or national research committee and the 1964 Declaration of Helsinki and its subsequent amendments or comparable ethical standards. Study was approved by the Ethics Committee of XXX City Hospital,(31.03.2021, E1-21-1699)

Geriatrik Popülasyonda Prognostik Nutrisyonel İndex ve Covid19 Mortalite İlişkisi

Abstract

Giriş: COVID-19 enfeksiyonu geçiren yaşlı hastalarda prognostik nutrisyonel indeksin (PNI) prognoz ve mortalite üzerindeki etkisini araştırmayı amaçladık. Gereç ve Yöntemler: Çalışmaya dahil edilen 401 hasta, tümü 65 yaş üstü idi. PNI laboratuvar ve demografik verilerle karşılaştırıldı.
Bulgular: Değerlendirme 181'i (%45) kadın ve ortanca yaşı 75.8±7.7 yıl olan 401 hasta üzerinde yapıldı. Üç yüz iki (%75.4) hasta iyileşen gruptaydı. Ortalama PNI değeri iyileşen grupta 41.9±5.9, eksitus grubunda 36.9±7 idi (p<0.001). Çok değişkenli lojistik regresyon analizine göre, COVID-19 hastalarında ileri yaş, yüksek maksimum ferritin düzeyi, yüksek maksimum IL-6 düzeyi ve PNI<40 mortaliteyi öngörmede bağımsız risk faktörleri olarak belirlendi. Sonuç: PNI skorlama sistemini içeren prognostik modellerin COVID-19 progresyonunu değerlendirmede ve hasta takibini geliştirmede faydalı olduğu bulunmuştur. Çalışmamıza dahil edilen hastaların tamamı geriatrik yaş grubunda olduğundan elde ettiğimiz veriler özellikle bu yaş grubundaki hastalarda COVID-19 enfeksiyonunun seyrine kılavuz olabilir.

Keywords

Beslenme, Ölüm, SARS-COV-2, Yaşlı, Geriatri

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