saujs

Sakarya University Journal of Science

2147-835X

Sakarya University

10.16984/saufenbilder.1338063

Biochemistry and Cell Biology (Other)

Biyokimya ve Hücre Biyolojisi (Diğer)

Identification and Characterization of the CPP Gene Family in the Genome of Aedes aegypti L. (Yellow Fever Mosquito) (Diptera: Culicidae)

https://orcid.org/0000-0003-2900-1755

Turan

Murat

ERZURUM TECHNICAL UNIVERSITY

12 18 2023

27 6 1174 1184 08 04 2023 10 03 2023

1997

Sakarya University Journal of Science

Aedes aegypti is an important vector organism responsible for carrying numerous arboviral pathogens and serious diseases, including yellow fever, Zika, Chikungunya, and Dengue fever. The CPP gene family, one of the crucial molecular defense systems, plays a significant role in the regulation of growth and development by controlling the production of proteins. In this study, a comprehensive genome analysis of the CPP gene family in Ae. aegypti was conducted. Each gene was thoroughly characterized, gene structures were examined, and conserved motifs were investigated. Additionally, the properties of these proteins were comprehensively analyzed. Expression analyses were performed to reveal the effects of CPP genes on development by calculating Reads Per Kilobase Million (RPKM) values. The findings emphasize the importance of CPP genes in controlling arboviral pathogens and understanding general stress responses in insects. The information derived from this research could contribute to the development of more effective intervention strategies for Ae. aegypti and other vector carriers to cope with stress. In conclusion, the systematic analysis of the CPP gene family in the Ae. aegypti genome is a crucial step in the management and development of effective disease prevention strategies for this species. Moreover, this study provides a significant foundation for future functional genomics research in understanding the structure and function of CPP genes.

Aedes aegypti CPP gene family Yellow fever mosquito Characterization

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