<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="research-article"        dtd-version="1.4">
            <front>

                <journal-meta>
                                                                <journal-id>smj</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Samsun Medical Journal</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">3023-669X</issn>
                                                                                            <publisher>
                    <publisher-name>Samsun University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Emergency Medicine</subject>
                                                            <subject>Infectious Diseases</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Acil Tıp</subject>
                                                            <subject>Bulaşıcı Hastalıklar</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Impact of Rabies Exposure Cases on Emergency Department Visits in Kırşehir</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="tr">
                                    <trans-title>Kırşehir’de Kuduz Riskli Temas Olgularının Acil Servis Başvurularına Etkisi</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-1146-6311</contrib-id>
                                                                <name>
                                    <surname>Çelik</surname>
                                    <given-names>Nazlı</given-names>
                                </name>
                                                                    <aff>Ataşehir İlçe Sağlık Müdürlüğü</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-2083-8348</contrib-id>
                                                                <name>
                                    <surname>Atalay</surname>
                                    <given-names>Halil İbrahim</given-names>
                                </name>
                                                                    <aff>KIRŞEHİR T.C. SB. AHİ EVRAN ÜNİVERSİTESİ KIRŞEHİR EĞİTİM VE ARAŞTIRMA HASTANESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-0942-1229</contrib-id>
                                                                <name>
                                    <surname>Eroğlu</surname>
                                    <given-names>Sercan</given-names>
                                </name>
                                                                    <aff>KIRŞEHİR AHİ EVRAN ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-6746-4083</contrib-id>
                                                                <name>
                                    <surname>Çelik</surname>
                                    <given-names>Burak</given-names>
                                </name>
                                                                    <aff>SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL FATİH SULTAN MEHMET SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, ACİL TIP ANABİLİM DALI</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-7370-420X</contrib-id>
                                                                <name>
                                    <surname>Çalışkan</surname>
                                    <given-names>Hacı Mehmet</given-names>
                                </name>
                                                                    <aff>KIRŞEHİR AHİ EVRAN ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20260430">
                    <day>04</day>
                    <month>30</month>
                    <year>2026</year>
                </pub-date>
                                        <volume>4</volume>
                                        <issue>1</issue>
                                        <fpage>28</fpage>
                                        <lpage>34</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20251219">
                        <day>12</day>
                        <month>19</month>
                        <year>2025</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20260205">
                        <day>02</day>
                        <month>05</month>
                        <year>2026</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2023, Samsun Medical Journal</copyright-statement>
                    <copyright-year>2023</copyright-year>
                    <copyright-holder>Samsun Medical Journal</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Aim: This study aimed to analyze the demographic and clinical characteristics, exposure types, and post-exposure prophylaxis (PEP) management of patients presenting to the emergency department in Kırşehir due to rabies-risk contact. It also sought to identify factors influencing vaccination completion and to provide data that may guide public health interventions and policy planning.Method: This retrospective, descriptive study was conducted at Kırşehir Training and Research HospitalEmergency Department and included all patients who presented with suspected rabies exposure betweenMarch 1, 2022, and March 1, 2023. Patients with incomplete records or those who only received follow-upvaccine doses initiated elsewhere were excluded. Data was collected from hospital information systems andPEP registration logs. Statistical analyses were performed using chi-square and Fisher’s exact tests, with p  &amp;lt;0.05 considered significant.Results: A total of 488 patients were included in the study. Male patients accounted for 55.5% of the cases.The majority of exposures were caused by cats (66.8%) and dogs (32.2%), with stray and unvaccinatedanimals responsible for most incidents (87.1%). The most frequently affected body parts were the right and left hands. Four vaccine doses were administered to 98.2% of patients, and immunoglobulin was given to 31.4%. Observation was performed in 12.7% of patients. A significant relationship was found between gender and type of attack, as well as between gender and animal species (p  &amp;lt; 0.001).Conclusion: This study highlights that rabies-risk exposures in Kırşehir are predominantly associated withstray, unvaccinated cats, and that the right hand is the most injured region. Although PEP adherence was high, the lack of observation and limited infectious disease consultations highlight areas requiring improvement. Enhancing interdepartmental coordination, strengthening stray animal vaccination programs, and improving community education are essential for optimizing rabies prevention and control strategies in Turkey.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="tr">
                            <p>Amaç: Bu çalışma, Kırşehir’de kuduz riskli temas nedeniyle acil servise başvuran hastaların demografik veklinik özelliklerini, temas türlerini ve maruziyet sonrası profilaksi (post eksposure profilaksi- PEP) süreçlerinianaliz etmeyi amaçlamıştır. Ayrıca, aşı tamamlama oranlarını etkileyen faktörleri belirleme ve halk sağlığımüdahaleleri ile politika planlamalarına veri sağlamayı hedeflemiştir.Yöntem: Bu retrospektif, tanımlayıcı çalışma Kırşehir Eğitim ve Araştırma Hastanesi Acil Servisi’ndeyürütülmüş olup, 1 Mart 2022 – 1 Mart 2023 tarihleri arasında kuduz şüphesiyle başvuran tüm hastalarıkapsamaktadır. Kayıtları eksik olan veya başka merkezde başlatılan aşıların devam dozlarını almak içinbaşvuran hastalar çalışma dışı bırakılmıştır. Veriler, hastane bilgi yönetim sistemi ve kuduz profilaksi kayıtdefterlerinden elde edilmiştir. İstatistiksel analizlerde ki-kare ve fishers exact testleri kullanılmış, p</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Rabies</kwd>
                                                    <kwd>  Post-exposure prophylaxis</kwd>
                                                    <kwd>  Rabies vaccines</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="tr">
                                                    <kwd>Kuduz</kwd>
                                                    <kwd>  Maruziyet sonrası profilaksi</kwd>
                                                    <kwd>  Kuduz aşıları</kwd>
                                            </kwd-group>
                                                                                                        <funding-group specific-use="FundRef">
                    <award-group>
                                                    <funding-source>
                                <named-content content-type="funder_name">none</named-content>
                            </funding-source>
                                                                    </award-group>
                </funding-group>
                                </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">1. WHO (World Health Organization) South-East Asia. Zero human dog-mediated rabies deaths by 2030 (“Zero
by 30”) [Internet]. https://www.who.int/southeastasia/health-topics/rabies/rabies-zero-deaths-by-2030. (Date
of access: 21 Dec 2025).</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">2. Glazier E, Fleenor LM, Dillon R. The impact of a walk-in clinic referral protocol on rabies vaccination
emergency department visits. Am J Emerg Med. 2025;95:30-3.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">3. Lewis T, Baack K, Gomez L, Nichols H, Lemmons C, Zeger W. Rabies post-exposure prophylaxis in the
emergency department. Am J Emerg Med. 2024;78:202-5.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">4. Singkam N, Sapsirisavat V, Chanduan J, Piyabenjarad P, Limpitigranon P, Wisitthipakdeekul S, et al. Delayed
and incomplete rabies post-exposure prophylaxis among international travelers: A seven-year retrospective
study at an emergency center in eastern Thailand. Travel Med Infect Dis. 2025;67:102873.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">5. Ayesha D, Snigdha S, Sneha B, Ipsa M. Economic costs of rabies post-exposure prophylaxis and healthcare
utilization patterns post animal bites: An experience from a private healthcare facility in Bhubaneswar, Odisha,
India. J Fam Med Prim Care. 2025;14(6):2201-9.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">6. Alpar S, Colak FU, Kaya B, Yilmaz S. The impact of media on surge capacity in emergency departments: A
study on rabies vaccination uptake. BMC Emerg Med. 2025;25(1):102.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">7. Aylan O, Sertkaya B, Demeli A, Vos A, Hacioglu S, Atıcı YT, et al. Oral rabies vaccination of foxes in Türkiye,
2019-2022. One Health. 2024;19:100877.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">8. WHO (World Health Organization) News. Gavi to boost access to life-saving human rabies vaccines in over 50
countries: Gavi, WHO and UAR [Internet]. https://www.who.int/news/item/13-06-2024-gavi-to-boost-access-
to-life-saving-rabies-vaccines-human-in-over-50-countries-gavi-who-and-uar. (Date of access: 21 Dec 2025).</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">9. Fooks AR, Banyard AC, Horton DL, Johnson N, McElhinney LM, Jackson AC. Current status of rabies and
prospects for elimination. Lancet. 2023;401(10378):1505-17.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">10. WHO (World Health Organization). Rabies: Key facts [Internet]. Geneva: WHO; 2024 Jun. https://www.who.
int/news-room/fact-sheets/detail/rabies. (Date of access: 21 Dec 2025).</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">11. Debbarma M, Singh R, Roychoudhury P, Das P, Nath A, Sharma K, et al. Rabies in cats: Implications, diagnosis,
and future directions. Bio Vet Innov. 2024;3(4):55-63.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">12. Sönmez ÖF. Stray dogs in Türkiye: A health needs assessment proposal for rabies elimination. J Biotechnol
Strateg Health Res. 2024;8(1):16-22.</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">13. CDC Yellow Book: Health Information for International Travel - Rabies [Internet]. 2025 Apr 23. https://www.
cdc.gov/yellow-book/hcp/travel-associated-infections-diseases/rabies.html. (Date of access: 21 Dec 2025).</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
