Year 2019, Volume 43 , Issue 4, Pages 523 - 531 2019-08-01

A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results

Alessandro Di CERBO [1] , Gianandrea GUIDETTI [2] , Sergio CANELLO [3] , Raffaella COCCO [4]


Based on the increase of food-related disturbances in animals and the recent findings concerning the toxicity of oxytetracycline (OTC) presence within pet food, we compared the effectiveness of two commercially available diets in 36 bitches suffering from reproductive disturbances. We ran a randomized clinical evaluation over a 90-day period. Bitches were randomly assigned to receive a control diet (CD) or a nutraceutical diet (ND) and were assessed for the presence of OTC in their sera before and at the end of the study. Sixteen of 18 bitches in the ND group went into heat within an average of 35.5 ± 3.1 days, and 15 of them became pregnant. In the CD group, 12 of 18 bitches went into heat within an average of 54.1 ± 3.2 days, and 10 of them became pregnant. A significant decrease in mean OTC serum concentration was observed in bitches belonging to the CD and ND group (P < 0.01). The overall amelioration, in particular in the ND group, provides new insights for future studies involving the modification of diet in order to restore the normal physiology of bitches suffering from reproductive disturbances.
Bitches, reproductive disturbances, control diet, nutraceutical diet, oxytetracycline
Primary Language en
Journal Section Articles
Authors

Author: Alessandro Di CERBO

Author: Gianandrea GUIDETTI

Author: Sergio CANELLO

Author: Raffaella COCCO

Dates

Publication Date : August 1, 2019

Bibtex @ { tbtkveterinary663575, journal = {Turkish Journal of Veterinary and Animal Sciences}, issn = {1300-0128}, eissn = {1303-6181}, address = {}, publisher = {TUBITAK}, year = {2019}, volume = {43}, pages = {523 - 531}, doi = {}, title = {A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results}, key = {cite}, author = {Cerbo, Alessandro Di and Guıdettı, Gianandrea and Canello, Sergio and Cocco, Raffaella} }
APA Cerbo, A , Guıdettı, G , Canello, S , Cocco, R . (2019). A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results . Turkish Journal of Veterinary and Animal Sciences , 43 (4) , 523-531 . Retrieved from https://dergipark.org.tr/en/pub/tbtkveterinary/issue/50868/663575
MLA Cerbo, A , Guıdettı, G , Canello, S , Cocco, R . "A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results" . Turkish Journal of Veterinary and Animal Sciences 43 (2019 ): 523-531 <https://dergipark.org.tr/en/pub/tbtkveterinary/issue/50868/663575>
Chicago Cerbo, A , Guıdettı, G , Canello, S , Cocco, R . "A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results". Turkish Journal of Veterinary and Animal Sciences 43 (2019 ): 523-531
RIS TY - JOUR T1 - A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results AU - Alessandro Di Cerbo , Gianandrea Guıdettı , Sergio Canello , Raffaella Cocco Y1 - 2019 PY - 2019 N1 - DO - T2 - Turkish Journal of Veterinary and Animal Sciences JF - Journal JO - JOR SP - 523 EP - 531 VL - 43 IS - 4 SN - 1300-0128-1303-6181 M3 - UR - Y2 - 2020 ER -
EndNote %0 Turkish Journal of Veterinary and Animal Sciences A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results %A Alessandro Di Cerbo , Gianandrea Guıdettı , Sergio Canello , Raffaella Cocco %T A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results %D 2019 %J Turkish Journal of Veterinary and Animal Sciences %P 1300-0128-1303-6181 %V 43 %N 4 %R %U
ISNAD Cerbo, Alessandro Di , Guıdettı, Gianandrea , Canello, Sergio , Cocco, Raffaella . "A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results". Turkish Journal of Veterinary and Animal Sciences 43 / 4 (August 2019): 523-531 .
AMA Cerbo A , Guıdettı G , Canello S , Cocco R . A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results. Turkish Journal of Veterinary and Animal Sciences. 2019; 43(4): 523-531.
Vancouver Cerbo A , Guıdettı G , Canello S , Cocco R . A possible correlation between diet, serum oxytetracycline concentration, and onset of reproductive disturbances in bitches: clinical observations and preliminary results. Turkish Journal of Veterinary and Animal Sciences. 2019; 43(4): 523-531.