Abstract
Amiodaron yaygın olarak kullanılan antiaritmik bir ilaçtır. Tiroid fonksiyon bozukluğu, bradikardi, hepatit, korneada mikrodepozitler ve ışığa duyarlılık artışı olmak üzere birçok yan etkilere sahip olduğu bilinmektedir. Bu etkilerin birçoğu uzun süreli amiodaron kullanımına bağlı dokuda birikmesiyle ilişkilidir. Kısa süreli amiodaron kullanımına bağlı akut hepatit, böbrek yetmezliği, akut pankreatit, yaygın kas krampları ve şiddetli karın ağrısı nadir görülen akut yan etkiler olarak bilinmektedir. Literatürde amiodaron yükleme tedavisi sırasında şiddetli karın ağrısıyla seyreden olgu bildirimlerine rastlamadık. İntravenöz amiodaron yüklemesi sırasında şiddetli karın ağrısına yol açan ve tedavi yönteminin değiştirilmesine neden olan amiodaronun, bu nadir görülen yan etkisine dikkat çekmek için olgumuz sunulmuştur.
Keywords
References
- Chen YY, Chen CY, Leung KK. Acute pancreatitis and amiodarone: A case report. World J Gastroenterol 2007;13:975-7.
- Rhodes A, Eastwood JB, Smith SA. Early acute hepatitis with parenteral amiodarone: a toxic effect of the vehicle? Gut 1993;34:565-6.
- Roy D, Talajic M, Dorian P, Connolly S, Eisenberg MJ, Green M, et al. Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators. N Engl J Med 2000;342:913- 20.
- Cataldi A, Gonella D, Robutti N, Siri M, Buonocore S, Odetti P. Hepatotoxicity after intravenous amiodarone. Aging Clin Exp Res 2008;20:593-6.
- Connolly SJ. Evidence-based analysis of amiodarone efficacy and safety. Circulation 1999;100:2025-34.
- Willis MS, Lugo AM. Amiodarone-induced neurotoxicity. Am J Health Syst Pharm 2009;66:567-9.
- Path GJ, Dai XZ, Schwartz JS, Benditt DG, Bache RJ. Effects of amiodarone with and without polysorbate 80 on myocardial oxygen consumption and coronary blood flow during treadmill exercise in the dog. J Cardiovasc Pharmacol 1991;18:11-6.
Abstract
Amiodarone, commonly used antiarrhythmic drug, has many side effects including thyroid function disorder, bradycardia, corneal microdeposits, hepatitis and increased sensitivity to light. Most of these effects result from accumulation of amiodarone in tissue, which is a consequence of long-term usage of this drug. Acute hepatitis, renal failure, acute pancreatitis, widespread muscle cramps and severe abdominal pain due to short-term use of amiodarone are rare acute side effects. However, we have not found any case reports in the literature about severe abdominal pain during a loading dose of amiodarone. With this case report, we aim to emphasize this rare side effect of amiodarone where a change in treatment is required
Keywords
References
- Chen YY, Chen CY, Leung KK. Acute pancreatitis and amiodarone: A case report. World J Gastroenterol 2007;13:975-7.
- Rhodes A, Eastwood JB, Smith SA. Early acute hepatitis with parenteral amiodarone: a toxic effect of the vehicle? Gut 1993;34:565-6.
- Roy D, Talajic M, Dorian P, Connolly S, Eisenberg MJ, Green M, et al. Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators. N Engl J Med 2000;342:913- 20.
- Cataldi A, Gonella D, Robutti N, Siri M, Buonocore S, Odetti P. Hepatotoxicity after intravenous amiodarone. Aging Clin Exp Res 2008;20:593-6.
- Connolly SJ. Evidence-based analysis of amiodarone efficacy and safety. Circulation 1999;100:2025-34.
- Willis MS, Lugo AM. Amiodarone-induced neurotoxicity. Am J Health Syst Pharm 2009;66:567-9.
- Path GJ, Dai XZ, Schwartz JS, Benditt DG, Bache RJ. Effects of amiodarone with and without polysorbate 80 on myocardial oxygen consumption and coronary blood flow during treadmill exercise in the dog. J Cardiovasc Pharmacol 1991;18:11-6.
Details
| Other ID | JA98UG83ZF |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | April 1, 2017 |
| Submission Date | April 1, 2017 |
| Published in Issue | Year 2017 Volume: 11 Issue: 1 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.