Abstract
Çocukluk çağı hematolojik malignitelerinin tedavisinde elde edilen başarıların ve sağ kalım oranlarının artması ile destek tedavilerinde ve tedavi ile ilişkili morbiditenin azaltılmasında beslenmenin rolü de giderek artmaktadır. Daha yoğun tedavi protokollerinin kullanımı ve/veya tek başına birincil hastalık, çocukların besinsel durumları üzerinde olumsuz etkiye sahip olabilir. Yetişkinlerin tedavisi için kullanılan terapilerle karşılaştırıldığında, hematolojik maligniteli çocuklarda çok modelli terapiler ve kombinasyon kemoterapileri etkin hale gelmiş ve %90 civarında genel iyileşme oranı sağlamıştır. Çocuklar metabolik olarak yetişkinlerden farklıdır, yıllarca olmasa bile, aylarca süren tedavileri boyunca büyüme ve gelişimlerinin de devam etmesi beklenmektedir. Yetersiz beslenme ve malignite kaşeksisi pediyatrik hematolojik malignitelerin ve tedavisinin yaygın bir sonucudur. Kaşeksiye neden olan malignite varlığında metabolik değişimlerin ve besin dengesini korumanın öneminin iyi anlaşılması bu çocukların bakımını sağlamanın önemli bir unsurudur. Benzer bir şekilde besinsel destek, tedavi başarısını artırabilir, komplikasyonları azaltabilir, immünolojik durumu iyileştirebilir ve sağ kalımı artırabilir. Besinsel destek programları, protein enerji malnutrisyonunun etkilerini engellemek veya tersine çevirmek ve çocuğun vücut sağlığını güçlendirmek için destek bakımın ana unsuru olarak değerlendirilmelidir.
Keywords
References
- Selwood K, Ward E, Gibson F. Assessment and management of nutritional challenges in children’s cancer care: A survey of current practice in the United Kingdom. Eur J Oncol Nurs 2010;14:439-46.
- Kantar M. Kanserli çocuk beslenmesi. Klinik Tıp Pediatri Dergisi 2012;2:26-9.
- Dinler G. Çocuk Kanser hastalarında beslenme – Derleme. Güncel Pediatri 2009; 7: 31-6.
- Nething J, Ringwald-Smith K, Williams R, Hancock ML, Hale GA. Establishing the use of body mass index as an indicator of nutrition risk in children with cancer. JPEN J Parenter Enteral Nutr 2007;31:53-7.
- Oğuz A, Karadeniz C, Pelit M, Hasanoğlu A. Arm anthropometry in evaluation of malnutrition in children with cancer. Pediatr Hematol Oncol 1999;16:35-41.
- Tazi I, Hidane Z, Zafad S, Harif M, Benchekroun S, Riberio R. Nutritional status at diagnosis of children with malignancies in Casablanca. Pediatr Blood Cancer 2008;51:495-8.
- Elhasid R, Laor A, Lischinsky S, Postovsky S, Weyl Ben Arush M. Nutritional status of children with solid tumors. Cancer 1999;86:119-25.
- Kurugöl Z, Egemen A, Cetingül N, Kavakli K, Nişli G, Oztop S. Early determination of nutritional problems in pediatric cancer patients. Turk J Pediatr 1997;39:325-34.
- Uderzo C, Rovelli A, Bonomi M, Barzaghi A, Strada S, Balduzzi A, et al. Nutritional status in untreated children with acute leukemia as compared with children without malignancy. J Pediatr Gastroenterol Nutr 1996;23:34-7.
- Han-Markey T. Nutritional considerations in pediatric oncology. Semin Oncol Nurs 2000;16:146-51.
- Sacks N, Hwang WT, Lange BJ, Tan KS, Sandler ES, Rogers PC, et al. Proactive enteral tube feeding in pediatric patients undergoing chemotherapy. Pediatr Blood Cancer 2014;61:281-5.
Abstract
The role of nutritional support in ensuring higher survival rates and lower treatment-related morbidity rates in childhood hematological malignancies has been increasing. The pediatric population is metabolically different from adults, and their growth and development need to continue during their treatment. Malnutrition and cachexia due to both the malignancy and its treatment is a common finding among pediatric patients with hematological malignancies. Prevention of cachexia and maintaining the child’s balanced nutritional status is an exceptionally important part of the treatment in the presence of malignancy. Nutritional support may increase the response to treatment, decrease complications, improve the immunological status and increase survival. Nutritional support programs should be regarded as the chief element of supportive care to prevent protein-calorie malnutrition and to strengthen the body in childhood hematological malignancies
Keywords
References
- Selwood K, Ward E, Gibson F. Assessment and management of nutritional challenges in children’s cancer care: A survey of current practice in the United Kingdom. Eur J Oncol Nurs 2010;14:439-46.
- Kantar M. Kanserli çocuk beslenmesi. Klinik Tıp Pediatri Dergisi 2012;2:26-9.
- Dinler G. Çocuk Kanser hastalarında beslenme – Derleme. Güncel Pediatri 2009; 7: 31-6.
- Nething J, Ringwald-Smith K, Williams R, Hancock ML, Hale GA. Establishing the use of body mass index as an indicator of nutrition risk in children with cancer. JPEN J Parenter Enteral Nutr 2007;31:53-7.
- Oğuz A, Karadeniz C, Pelit M, Hasanoğlu A. Arm anthropometry in evaluation of malnutrition in children with cancer. Pediatr Hematol Oncol 1999;16:35-41.
- Tazi I, Hidane Z, Zafad S, Harif M, Benchekroun S, Riberio R. Nutritional status at diagnosis of children with malignancies in Casablanca. Pediatr Blood Cancer 2008;51:495-8.
- Elhasid R, Laor A, Lischinsky S, Postovsky S, Weyl Ben Arush M. Nutritional status of children with solid tumors. Cancer 1999;86:119-25.
- Kurugöl Z, Egemen A, Cetingül N, Kavakli K, Nişli G, Oztop S. Early determination of nutritional problems in pediatric cancer patients. Turk J Pediatr 1997;39:325-34.
- Uderzo C, Rovelli A, Bonomi M, Barzaghi A, Strada S, Balduzzi A, et al. Nutritional status in untreated children with acute leukemia as compared with children without malignancy. J Pediatr Gastroenterol Nutr 1996;23:34-7.
- Han-Markey T. Nutritional considerations in pediatric oncology. Semin Oncol Nurs 2000;16:146-51.
- Sacks N, Hwang WT, Lange BJ, Tan KS, Sandler ES, Rogers PC, et al. Proactive enteral tube feeding in pediatric patients undergoing chemotherapy. Pediatr Blood Cancer 2014;61:281-5.
Details
| Other ID | JA55JU34KZ |
|---|---|
| Journal Section | Collection |
| Authors | |
| Publication Date | June 1, 2015 |
| Submission Date | June 1, 2015 |
| Published in Issue | Year 2015 Volume: 9 Issue: 2 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.