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Anterior mediasten yerleşimli paratiroid adenomu

Year 2016, Volume: 7 Issue: 3, 83 - 85, 07.09.2016

Abstract

Primer hiperparatroidizme sebep olan paratroid lezyonlarının gerçek insidansı belirsizdir. Olguların en sık nedenini %75-80 adenomlar oluşturmaktadır. Benign hiperplaziler %10-15’inde, paratroid karsinomları ise %5’den azında sorumludurlar. Hiperparatroidizme neden olan paratroid adenomlarının %20-25’i ektopik yerleşimlidir. Biz bu olgu sunumunda anterior mediastende yer alan ektopik paratroid adenomu nedeniyle semptomatik hiperkalsemili olguyu tartıştık. Olguya mediyan sternotomi aracılığıyla timektomi ile ektopik paratroid rezeksiyonu uygulandı. Serum kalsiyum ve parathormon seviyeleri hızlı bir biçimde geriledi.

Anahtar Kelimeler: Ektopik, Paratroid, Primer, Hiperparatroidizm

References

  • -Enön S. Mediastenin Endokrin Tümörleri. Toraks Cerrahisi Bülteni. 2011; 2(2):124-35.
  • -Lee WS, Kim YH, Lee SA, Chee HK, Hwang JJ. Hyperparathyroidsm induced by heterotopic parathyroid adenoma in the anterior mediastinum. Turk Gogus Kalp Dama 2014;22(2):443-6.
  • -Çelik A, Aydın E, Yazıcı Ü, Karaoğlanoğlu N. Parathyroid Adenoma Located on Anterior Mediastinum and Hungry Bone Syndrome; Case ReportAnterior. J Clin Anal Med 2014;5(1): 69-71.
  • -Thompson NW, Eckhauser F, Harness J. The anatomy of primary hyperparathyroidism. Surgery 1982;92(5):814-21.
  • -Soler R, Bargiela A, Cordido F, Aguilera C, Argüeso R, Cao I. MRI of mediastinal parathyroid cystic adenoma causing hyperparathyroidism. J Comput Assist Tomogr 1996;20:166-8.
  • -Uludag M, Isgor A, Yetkin G, Atay M, Kebudi A, Akgun I. Supernumerary ectopic parathyroid glands. Persistent hyperparathyroidism due to mediastinal parathyroid adenoma localized by preoperative single photon emission computed tomography and intraoperative gamma probe application. Hormones (Athens) 2009;8:144-9.
  • -Moriyama T, Kageyama K, Nigawara T, et al. Diagnosis of a case of ectopic parathyroid adenoma on the early image of 99mTc- MIBI scintigram. Endocr J 2007;54(3):437-40.
  • -Uludag M, Isgor A, Yetkin G, Atay M, Kebudi A, Akgun I. Supernumerary ectopic parathyroid glands. Persistent hyperparathyroidism due to mediastinal parathyroid adenoma localized by preoperative single photon emission computed tomography and intraoperative gamma probe application. Hormones (Athens) 2009;8(2):144-9.
  • -Al-Mashat F, Sibiany A, Faleh D, Kary K, Alfi AY, El-Lakany MM. Mediastinal para-thyroid adenoma. Saudi J Kidney Dis Transpl 2009;20(5):826-30.
  • -Johnson NA, Tublin ME, Ogilvie JB. Parathyroid imaging: technique and role in the preoperative evaluation of primary hyperparathyroidism. AJR Am J Roentgenol 2007;188(6):1706-15.
  • -Tcherveniakov P, Menon A, Milton R, Papagiannopoulos K, Lansdown M, Thorpe JA. Video-assisted mediastinoscopy (VAM) for surgical resection of ectopic parathyroid adenoma. J Cardiothorac Surg 2007;2:41.

Parathyroid adenoma located on anterior mediastinum

Year 2016, Volume: 7 Issue: 3, 83 - 85, 07.09.2016

Abstract

The real incidence of parathyroid lesions causing primary hyperparathyroidism is unclear. Adenomas are the most common cause constitute 75-80 % of the cases. Benign hyperplasia responsible for 10-15%, and the parathyroid carcinoma less than 5%. Parathyroid adenomas causing to hyperparathyroidism may present an ectopic localization at 20-25% of the patients. Here we discuss a case of symptomatic hypercalcemia, due to an ectopic parathyroid adenoma in the anterior mediastinum. She was treated by ectopic parathyroid removal along with thymectomy, approached by median sternotomy. Serum calcium and parathyroid hormone levels were normalized immediately.

Key Words: Ectopic, Parathyroid, Primary, Hyperparathyroidism

 

 

References

  • -Enön S. Mediastenin Endokrin Tümörleri. Toraks Cerrahisi Bülteni. 2011; 2(2):124-35.
  • -Lee WS, Kim YH, Lee SA, Chee HK, Hwang JJ. Hyperparathyroidsm induced by heterotopic parathyroid adenoma in the anterior mediastinum. Turk Gogus Kalp Dama 2014;22(2):443-6.
  • -Çelik A, Aydın E, Yazıcı Ü, Karaoğlanoğlu N. Parathyroid Adenoma Located on Anterior Mediastinum and Hungry Bone Syndrome; Case ReportAnterior. J Clin Anal Med 2014;5(1): 69-71.
  • -Thompson NW, Eckhauser F, Harness J. The anatomy of primary hyperparathyroidism. Surgery 1982;92(5):814-21.
  • -Soler R, Bargiela A, Cordido F, Aguilera C, Argüeso R, Cao I. MRI of mediastinal parathyroid cystic adenoma causing hyperparathyroidism. J Comput Assist Tomogr 1996;20:166-8.
  • -Uludag M, Isgor A, Yetkin G, Atay M, Kebudi A, Akgun I. Supernumerary ectopic parathyroid glands. Persistent hyperparathyroidism due to mediastinal parathyroid adenoma localized by preoperative single photon emission computed tomography and intraoperative gamma probe application. Hormones (Athens) 2009;8:144-9.
  • -Moriyama T, Kageyama K, Nigawara T, et al. Diagnosis of a case of ectopic parathyroid adenoma on the early image of 99mTc- MIBI scintigram. Endocr J 2007;54(3):437-40.
  • -Uludag M, Isgor A, Yetkin G, Atay M, Kebudi A, Akgun I. Supernumerary ectopic parathyroid glands. Persistent hyperparathyroidism due to mediastinal parathyroid adenoma localized by preoperative single photon emission computed tomography and intraoperative gamma probe application. Hormones (Athens) 2009;8(2):144-9.
  • -Al-Mashat F, Sibiany A, Faleh D, Kary K, Alfi AY, El-Lakany MM. Mediastinal para-thyroid adenoma. Saudi J Kidney Dis Transpl 2009;20(5):826-30.
  • -Johnson NA, Tublin ME, Ogilvie JB. Parathyroid imaging: technique and role in the preoperative evaluation of primary hyperparathyroidism. AJR Am J Roentgenol 2007;188(6):1706-15.
  • -Tcherveniakov P, Menon A, Milton R, Papagiannopoulos K, Lansdown M, Thorpe JA. Video-assisted mediastinoscopy (VAM) for surgical resection of ectopic parathyroid adenoma. J Cardiothorac Surg 2007;2:41.
There are 11 citations in total.

Details

Journal Section Case Report
Authors

Rasih Yazkan

Kadir Çeviker

Bünyamin Aydın This is me

Azime Aslıhan İlhan This is me

İbrahim Metin Çiriş

Publication Date September 7, 2016
Published in Issue Year 2016 Volume: 7 Issue: 3

Cite

APA Yazkan, R., Çeviker, K., Aydın, B., İlhan, A. A., et al. (2016). Anterior mediasten yerleşimli paratiroid adenomu. Turkish Journal of Clinics and Laboratory, 7(3), 83-85.
AMA Yazkan R, Çeviker K, Aydın B, İlhan AA, Çiriş İM. Anterior mediasten yerleşimli paratiroid adenomu. TJCL. September 2016;7(3):83-85.
Chicago Yazkan, Rasih, Kadir Çeviker, Bünyamin Aydın, Azime Aslıhan İlhan, and İbrahim Metin Çiriş. “Anterior Mediasten yerleşimli Paratiroid Adenomu”. Turkish Journal of Clinics and Laboratory 7, no. 3 (September 2016): 83-85.
EndNote Yazkan R, Çeviker K, Aydın B, İlhan AA, Çiriş İM (September 1, 2016) Anterior mediasten yerleşimli paratiroid adenomu. Turkish Journal of Clinics and Laboratory 7 3 83–85.
IEEE R. Yazkan, K. Çeviker, B. Aydın, A. A. İlhan, and İ. M. Çiriş, “Anterior mediasten yerleşimli paratiroid adenomu”, TJCL, vol. 7, no. 3, pp. 83–85, 2016.
ISNAD Yazkan, Rasih et al. “Anterior Mediasten yerleşimli Paratiroid Adenomu”. Turkish Journal of Clinics and Laboratory 7/3 (September 2016), 83-85.
JAMA Yazkan R, Çeviker K, Aydın B, İlhan AA, Çiriş İM. Anterior mediasten yerleşimli paratiroid adenomu. TJCL. 2016;7:83–85.
MLA Yazkan, Rasih et al. “Anterior Mediasten yerleşimli Paratiroid Adenomu”. Turkish Journal of Clinics and Laboratory, vol. 7, no. 3, 2016, pp. 83-85.
Vancouver Yazkan R, Çeviker K, Aydın B, İlhan AA, Çiriş İM. Anterior mediasten yerleşimli paratiroid adenomu. TJCL. 2016;7(3):83-5.


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