Effects of carbon monoxide poisoning on temperament

Year 2018, Volume: 9 Issue: 1, 19 - 24, 01.03.2018

Oğuz Eroğlu , Orhan Murat Koçak , Şadiye Visal Buturak , Figen Coşkun , Ayşe Gül Yılmaz Özpolat , Turgut Deniz

https://doi.org/10.18663/tjcl.311874

Abstract

Aim:
The aim of this study was to
investigate the effect of carbon monoxide
(CO) poisoning on temperament and
associated disorders.

Material
and Methods: The study was conducted in
healthy volunteers and patients
who presented to the Emergency Department of Kirikkale University Hospital after exposure to CO. Patients with a carboxyhemoglobin
level of ≥10% were considered
to have CO poisoning. Patients with
psychiatric disease or an illness that could increase CO levels and
those who smoked or
were using medication were
excluded. Healthy volunteers were evaluated once, and CO poisoning patients were
evaluated at the time of presentation
and 3 months after discharge using the Temperament Evaluation of Memphis, Pisa,
Paris, and San Diego
Autoquestionnaire (TEMPS-A) temperament scale. Repeated analysis of
variance was applied
for comparisons. A p
value of <0.05 was considered statistically significant.

Results:
The study included 110
participants: 68 in the CO poisoning group and 42 healthy volunteers. Significant
differences between the groups were observed in the TEMPS-A
scores for depressive type (p=0.016) and anxious type
(p=0.01) at first presentation and for
the irritability type (p=0.02) and anxious type
(p=0.034) at 3
months after the discharge.
When the temperament scale scores of the CO poisoning patients were compared according
to evaluation time (first presentation and 3
months after discharge), no significant
difference in temperament types was observed.

Conclusion:
Although the temperament types
related to depression and anxiety were affected after CO poisoning, they
did not
change completely.
Further research is
needed to better understand the
psychiatric effects of CO poisoning.

Keywords

Carbonmonoxide poisoning, emergency department, temperament, psychiatric disorders, temperament scale

Karbonmonoksit zehirlenmesinin mizaç üzerindeki etkisi

Abstract

Amaç: Bu
çalışma karbonmonoksit zehirlenmesinin mizaç ve ilişkili olduğu bozukluklar
üzerindeki etkisini araştırmak amacıyla yapılmıştır.

Gereç
ve Yöntemler: Çalışma Kırıkkale Üniversitesi hastanesi
acil servisine karbonmonoksit (CO) maruziyeti sebebiyle başvuran hastalar ve
sağlıklı gönüllü (SG) katılımcılarla yapıldı. Karboksihemoglobin düzeyi ≥%10
ölçülen hastalar KZ olarak kabul edildi. Psikiyatrik hastalığı veya ilaç
kullanımı olanlar ve CO düzeyini yükseltecek hastalığı veya sigara içiciliği
olanlar çalışmaya dahil edilmedi. SG bir kere, KZ olanlar ise acil servise ilk başvuru
anında taburcu edilirken ve taburcu olduktan üç ay sonra TEMPS-A (Temperament
Evaluation of Memphis, Pisa, Paris and San Diego-Autoquestionaire)
mizaç ölçeği ile değerlendirildi. Grupların karşılaştırılmasında
Repeated measures ANOVA testi kullanıldı ve p<0.05 anlamlı kabul
edildi. 

Bulgular: Çalışmaya
KZ (n=68) ve SG (n=42) olmak üzere toplam 110 katılımcı dahil edildi. Gruplar
TEMPS-A mizaç ölçeği puanları bakımından karşılaştırıldığında,  acil servise ilk başvuru anında Depresif (p=0.016)
ve Anksiyöz (p=0.01) mizaç, üçüncü ayda ise Irritable  (p=0.02) ve Anksiyöz (p=0.034) mizaç tipi
puanlarında anlamlı farklılık saptandı. KZ olan hastaların mizaç ölçeği
puanları, değerlendirme zamanına (İlk başvuru zamanı ve üçüncü ay) göre
karşılaştırıldığında hiçbir mizaç tipinde fark saptanmadı.

 

Sonuç: KZ
sonrası hastaların özellikle depresyon ve anksiyete ile ilişkisi olan mizaç
tiplerinde etkilenme olsa da, mizaç özellikleri tamamen değişmemiştir.
Karbonmonoksit zehirlenmesinin psikiyatrik etkilerinin daha iyi anlaşılabilmesi
için ileri çalışmalara ihtiyaç vardır.

Keywords

acil servis, mizaç, Karbomonoksit zehirlenmesi, psikiyatrik bozukluklar, mizaç ölçeği

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