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            <front>

                <journal-meta>
                                                                <journal-id>turk j int med</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Turkish Journal of Internal Medicine</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2687-4245</issn>
                                                                                            <publisher>
                    <publisher-name>Nizameddin KOCA</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.46310/tjim.1290999</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>​Internal Diseases</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>İç Hastalıkları</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                                                            <article-title>Maternal and fetal outcomes in pregnant women with Takayasu’s arteritis: single center experience over ten years</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-0624-1986</contrib-id>
                                                                <name>
                                    <surname>Yağız</surname>
                                    <given-names>Burcu</given-names>
                                </name>
                                                                    <aff>BURSA ULUDAĞ ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-0298-4157</contrib-id>
                                                                <name>
                                    <surname>Coşkun</surname>
                                    <given-names>Belkıs Nihan</given-names>
                                </name>
                                                                    <aff>Bursa Uludağ Üniversitesi</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-1624-4339</contrib-id>
                                                                <name>
                                    <surname>Sakar</surname>
                                    <given-names>Orkun</given-names>
                                </name>
                                                                    <aff>Bursa Uludağ Üniversitesi</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-8645-2670</contrib-id>
                                                                <name>
                                    <surname>Dalkılıç</surname>
                                    <given-names>Hüseyin Ediz</given-names>
                                </name>
                                                                    <aff>Bursa Uludağ Üniversitesi</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-7054-5351</contrib-id>
                                                                <name>
                                    <surname>Pehlivan</surname>
                                    <given-names>Yavuz</given-names>
                                </name>
                                                                    <aff>Bursa Uludağ Üniversitesi</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20231029">
                    <day>10</day>
                    <month>29</month>
                    <year>2023</year>
                </pub-date>
                                        <volume>5</volume>
                                        <issue>4</issue>
                                        <fpage>224</fpage>
                                        <lpage>233</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20230502">
                        <day>05</day>
                        <month>02</month>
                        <year>2023</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20230728">
                        <day>07</day>
                        <month>28</month>
                        <year>2023</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2019, Turkish Journal of Internal Medicine</copyright-statement>
                    <copyright-year>2019</copyright-year>
                    <copyright-holder>Turkish Journal of Internal Medicine</copyright-holder>
                </permissions>
            
                                                                                                                        <abstract><p>Background: This study aims to assess pregnant women&#039;s maternal and fetal outcomes with Takayasu’s arteritis (TA).Material and Methods: The study comprised ten pregnant women at the time of diagnosis or afterwards among the 50 patients diagnosed with TA between 2003 and 2021. Twenty-one pregnancy outcomes of 10 patients were obtained from hospital records and telephonic interviews. Two pregnancies were excluded due to timing before diagnosis.Results: Based on the angiographic classification, six patients had type 1, two had type 2b, and two had type 1+4 TA. 63.15% of pregnancies were planned, and the rheumatologist approved 42.10%. Live birth occurred in 16 (84.2%) of 19 pregnancies, three pregnancies (15.7%) resulted in abortion and two (10.5 %) of 19 pregnancies ended in neonatal death. In five (26.3%) of the 19 pregnancies, the disease was activated during pregnancy. Two neonatal deaths were from the two patients diagnosed with preeclampsia during pregnancy. Pre-existing hypertension and active disease are shared features of these two patients. After one year of follow-up, six pregnancies (31.5%) had active disease, and four (66.6%) had active disease both before and during pregnancy. While fetal data analysis revealed no congenital anomalies, four pregnancies resulted in low birth weight and intrauterine growth retardation (21.05%).Conclusions: The risk of developing preeclampsia and neonatal death should be considered, especially in TA patients with pre-existing hypertension who become pregnant during active disease.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Disease activity</kwd>
                                                    <kwd>  pregnancy outcomes</kwd>
                                                    <kwd>  pre-existing hypertension</kwd>
                                                    <kwd>  Takayasu arteritis</kwd>
                                            </kwd-group>
                            
                                                                                                                                                    </article-meta>
    </front>
    <back>
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