Case Report
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Year 2022, Volume: 4 Issue: 2, 80 - 82, 29.04.2022
https://doi.org/10.46310/tjim.904114

Abstract

References

  • Barcellini W, Zaninoni A, Giannotta JA, Fattizzo B. New Insights in Autoimmune Hemolytic Anemia: From Pathogenesis to Therapy Stage 1. J Clin Med. 2020 Nov 27;9(12):3859. doi: 10.3390/jcm9123859.
  • Zhou J-C, Wu M-Q, Peng Z-M, Zhao W-H, Bai Z-J. Clinical analysis of 20 patients with non-Hodgkin lymphoma and autoimmune hemolytic anemia: A retrospective study. Medicine (Baltimore). 2020 Feb;99(7):e19015. doi: 10.1097/ MD.0000000000019015.
  • Doni E, Carli G, Di Rocco A, Sassone M, Gandolfi S, Patti C, Falisi E, Salemi C, Visco C. Autoimmune haemolytic anaemia in mantle cell lymphoma : an insidious complication associated with leukemic disease. Hematol Oncol. 2017 Mar;35(1):135-7. doi: 10.1002/hon.2241.
  • Sindel A, Al-Juhaishi T, Yazbeck V. Marginal zone lymphoma: State-of-the-art treatment. Curr Treat Options Oncol. 2019 Dec 5;20(12):90. doi:10.1007/s11864-019-0687-5.
  • Voinchet H, Etienne G, Ghiringelli CB, Pellegrin JL, Viallard JF, Parrens M, Longy-Boursier M. Splenic marginal zone lymphoma and autoimmunity: report of six cases. Rev Med Interne. 2010 Jan;31(1):4-11 (in French). doi: 10.1016/j. revmed.2009.05.003.
  • Piris MA, Arribas A, Mollejo M. Marginal zone lymphoma. Semin Diagn Pathol. 2011 May;28(2):135-45. doi: 10.1053/j. semdp.2011.03.001.
  • Hauswirth AW, Skrabs C, Schützinger C, Gaiger A, Lechner K, Jäger U. Autoimmune hemolytic anemias, Evans’ syndromes, and pure red cell aplasia in non-Hodgkin lymphomas. Leuk Lymphoma. 2007Jun;48(6):1139-49. doi: 10.1080/10428190701385173.

Marginal zone lymphoma presenting in a patient with autoimmune hemolytic anemia: a case report

Year 2022, Volume: 4 Issue: 2, 80 - 82, 29.04.2022
https://doi.org/10.46310/tjim.904114

Abstract

While autoimmune hemolytic anemia (AIHA) is expected in non-Hodgkin’s lymphomas, it is less common in marginal zone lymphoma. Sixty-year-old male patient was followed up with hemolytic anemia in our clinic and while the etiology was investigated, scattered nodes in the mediastinum and abdomen compatible with lymphoproliferative disease were observed on CT, and positive detection of CD5, CD19, CD20, CD22, CD45, HLA-DR, FMC-7 on flow cytometry sent from peripheral blood and a diagnosis of low grade B cell lymphoma (MZL) was made with the result of bone marrow pathology. We found it appropriate to present our MZL case because of its response to steroid treatment and its rare presentation with AIHA.

References

  • Barcellini W, Zaninoni A, Giannotta JA, Fattizzo B. New Insights in Autoimmune Hemolytic Anemia: From Pathogenesis to Therapy Stage 1. J Clin Med. 2020 Nov 27;9(12):3859. doi: 10.3390/jcm9123859.
  • Zhou J-C, Wu M-Q, Peng Z-M, Zhao W-H, Bai Z-J. Clinical analysis of 20 patients with non-Hodgkin lymphoma and autoimmune hemolytic anemia: A retrospective study. Medicine (Baltimore). 2020 Feb;99(7):e19015. doi: 10.1097/ MD.0000000000019015.
  • Doni E, Carli G, Di Rocco A, Sassone M, Gandolfi S, Patti C, Falisi E, Salemi C, Visco C. Autoimmune haemolytic anaemia in mantle cell lymphoma : an insidious complication associated with leukemic disease. Hematol Oncol. 2017 Mar;35(1):135-7. doi: 10.1002/hon.2241.
  • Sindel A, Al-Juhaishi T, Yazbeck V. Marginal zone lymphoma: State-of-the-art treatment. Curr Treat Options Oncol. 2019 Dec 5;20(12):90. doi:10.1007/s11864-019-0687-5.
  • Voinchet H, Etienne G, Ghiringelli CB, Pellegrin JL, Viallard JF, Parrens M, Longy-Boursier M. Splenic marginal zone lymphoma and autoimmunity: report of six cases. Rev Med Interne. 2010 Jan;31(1):4-11 (in French). doi: 10.1016/j. revmed.2009.05.003.
  • Piris MA, Arribas A, Mollejo M. Marginal zone lymphoma. Semin Diagn Pathol. 2011 May;28(2):135-45. doi: 10.1053/j. semdp.2011.03.001.
  • Hauswirth AW, Skrabs C, Schützinger C, Gaiger A, Lechner K, Jäger U. Autoimmune hemolytic anemias, Evans’ syndromes, and pure red cell aplasia in non-Hodgkin lymphomas. Leuk Lymphoma. 2007Jun;48(6):1139-49. doi: 10.1080/10428190701385173.
There are 7 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Reports
Authors

Büşra Güner 0000-0001-6320-9512

Bedrettin Orhan 0000-0003-3970-2344

Tuba Ersal 0000-0001-5419-3221

Vildan Ozkocaman 0000-0003-0014-7398

Rıdvan Ali 0000-0001-6486-3399

Fahir Özkalemkaş

Early Pub Date July 31, 2021
Publication Date April 29, 2022
Submission Date March 26, 2021
Acceptance Date November 26, 2021
Published in Issue Year 2022 Volume: 4 Issue: 2

Cite

EndNote Güner B, Orhan B, Ersal T, Ozkocaman V, Ali R, Özkalemkaş F (April 1, 2022) Marginal zone lymphoma presenting in a patient with autoimmune hemolytic anemia: a case report. Turkish Journal of Internal Medicine 4 2 80–82.

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