tjr Türk Resüsitasyon Dergisi 2822-3284 Resüsitasyon Derneği Anaesthesiology Anesteziyoloji SUGAMMADEKS UYGULAMASI ARDINDAN GELİŞEN ANAFİLAKTİK ŞOK VE KARDİYAK ARREST ANAPHYLACTIC SHOCK AND CARDIAC ARREST FOLLOWING SUGAMMADEX ADMINISTRATION https://orcid.org/0009-0007-6606-5455 Özçelik Sinem DOKUZ EYLÜL ÜNİVERSİTESİ, DOKUZ EYLÜL ÜNİVERSİTESİ HASTANESİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ https://orcid.org/0009-0008-0035-0373 Özler Helin DOKUZ EYLÜL ÜNİVERSİTESİ, DOKUZ EYLÜL ÜNİVERSİTESİ HASTANESİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ https://orcid.org/0000-0001-5534-7579 Küçük Onur DOKUZ EYLÜL ÜNİVERSİTESİ, DOKUZ EYLÜL ÜNİVERSİTESİ HASTANESİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ 12 29 2025 4 S2 13 14 11 01 2025 11 08 2025 Copyright © 2022, Turkish Journal of Resuscitation 2022 Turkish Journal of Resuscitation

Sugammadeks, aminosteroid yapılı nöromüsküler blokörlerin selektif antagonizasyonu amacıyla kullanılan bir ajandır. Genelde neostigmine göre daha güvenli kabul edilmesine rağmen (1), perioperatif dönemde ani hipotansiyon, bradikardi, dolaşım kollapsı ve hatta kardiyak arrest ile seyreden aşırı duyarlılık reaksiyonları bildirilmiştir (2–4). Bu olgu sunumunda, operasyon bitiminde sugammadeks uygulanmasını takiben dakikalar içinde gelişen hemodinamik kollaps, kardiyak arrest ve başarılı resüsitasyon sürecini sunmayı amaçladık.

Sugammadex selectively antagonizes aminosteroid neuromuscular blockers. Although regarded as safer than neostigmine (1), perioperative hypersensitivity has been reported, presenting with sudden hypotension, bradycardia, circulatory collapse, and cardiac arrest (2–4). We present hemodynamic collapse, cardiac arrest, and successful resuscitation occurring within minutes following sugammadex administration at the end of the operation.

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